Bratislav Misic (@misicbata) - Twitter Profili | Zamantika Mersobahis Locabet

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Towards a biologically annotated brain connectome | doi.org/10.1038/s41583… How do we integrate local biological annotations with connectome wiring? @VinceBazz + @JustineYHansen lay out how to build and analyze annotated connectomes @NatRevNeurosci ⤵️

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Andrew Zalesky@AndrewZalesky·2d

Disease biology is heterogeneous, but most research reduces it to group means NEW WORK characterizing HETEROGENEITY in BRAIN and BIOCHEMICAL biomarkers across >1/2 million people & >30 disorders: nature.com/articles/s4146… Check out the online resource: tinyurl.com/bdecwsnb

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Juergen Dukart@DukartJuergen·2 May

🔬 New preprint: We introduce NEOFC—a framework linking brain connectivity to neurotransmitter systems. Reveals robust neurochemical signatures, strong noradrenergic effects, and sensitivity to drugs & psychosis. 📄 biorxiv.org/content/10.648… #Neuroscience #Neuroimaging

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Andrew Zalesky@AndrewZalesky·14 Nis

Polysynaptic routes in the WHITE MATTER CONNECTOME reveal neuroanatomical basis for TMS therapy Shorter anatomical routes between stimulation site & deep brain target predict superior response A step fwd for Network Neuroscience! Out now: @NatureNeuro rdcu.be/fdl8x

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Jake Vogel@_JakeVogel_·31 Mar

The lab's first published paper is here and I could not be more excited!! If you're interested in proteomics, AI or both, it could be an interesting read. Congrats @anlijuncn for a great piece of work, and big shout out to our collaborators at @_neuroproteome and @biofinder_study

Lijun AN | 安丽军@anlijuncn

[1/7] Our work is now out in @NatureMedicine nature.com/articles/s4159… We developed a state-of-the-art AI-proteomics model for diagnosing multiple neurodegenerative diseases from blood plasma. See previous thread for a summary – but some updates in the published version described below. ProtAIDe-Dx now outperformed both classic machine learning models and even foundation models like TabPFN!

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Micah G. Allen@micahgallen·27 Mar

Neuropeptides act as diverse signaling molecules that regulate both basic bodily functions and complex cognitive processes within the human brain. doi.org/10.1038/s41593…

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Andrew Zalesky@AndrewZalesky·26 Mar

Mapping connectomes in disease? Check out our article on clinical connectomics in @NeuroCellPress - Tractography behavior in disease - How to measure connectivity - How pathology impacts each stage of connectome mapping - Multiscale connectomics cell.com/neuron/fulltex…

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Eric Ceballos@ericg_ceballos·18 Mar

Curious about how brain and body communicate, or how circuit states are regulated over seconds to hours? Read our paper about neuropeptide systems and how they contribute to neural architecture and function #neuroscience

Bratislav Misic@misicbata

Organization of neuropeptide systems in the human brain | doi.org/10.1038/s41593… Neuropeptides are functionally diverse signaling molecules in the brain and body. @ericg_ceballos curates an atlas of neuropeptide receptors and relates it to brain function @NatureNeuro 🧩 🧠 ⤵️

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Eric Ceballos@ericg_ceballos·18 Mar

Curious about how brain and body communicate, or how circuit states are regulated over seconds to hours? Read our paper about neuropeptide systems and how they contribute to neural architecture and function #neuroscience

Bratislav Misic@misicbata

Organization of neuropeptide systems in the human brain | doi.org/10.1038/s41593… Neuropeptides are functionally diverse signaling molecules in the brain and body. @ericg_ceballos curates an atlas of neuropeptide receptors and relates it to brain function @NatureNeuro 🧩 🧠 ⤵️

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Bratislav Misic@misicbata·17 Mar

9⃣ Collectively, these results show that the neuropeptide receptors are highly organized across the human brain and closely intertwined with multiple features of brain structure and function. paper: rdcu.be/e8zTZ data + code: github.com/netneurolab/ce…

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Bratislav Misic@misicbata·17 Mar

8⃣ Finally, we replicate all findings using alternative processing and analytical choices. We also conduct multiple sanity check/domain knowledge experiments, including detailed analysis of peptides related to feeding, sexual dimorphism and vasomodulation.

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Bratislav Misic@misicbata·17 Mar

Organization of neuropeptide systems in the human brain | doi.org/10.1038/s41593… Neuropeptides are functionally diverse signaling molecules in the brain and body. @ericg_ceballos curates an atlas of neuropeptide receptors and relates it to brain function @NatureNeuro 🧩 🧠 ⤵️

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Andrea Luppi@loopyluppi·13 Mar

Just out in @NatureNeuro!🧠“Competitive interactions shape mammalian brain network dynamics and computation” nature.com/articles/s4159… Is large-scale brain communication purely cooperative — or is competition a core organizing principle? We built 🧠models to find out: read on🧵👇

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Justine Hansen@JustineYHansen·12 Mar

turns out there are many many different types of synapses, each with their own voltage dynamics and response properties (!) We dug into how synapse phenotype is associated with regional dynamics (awake rs-fMRI in mice) - see the publication and bratislav's tweeprint below:

Bratislav Misic@misicbata

Synaptome architecture shapes regional dynamics in the mouse brain | doi.org/10.1371/journa… How do diverse synapses relate to the spatial patterning of whole-brain dynamics? @JustineYHansen explores @PLOSBiology ⤵️

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