Michael Skaff

A new study suggests it may be possible to regenerate cartilage lost to aging or arthritis with an oral drug or local injection, rendering knee and hip replacement unnecessary. pulse.ly/z6a3o3yymj

Significant #flooding in Marin today. This was San Rafael an hour ago:

Carl Reiner gave Rob Reiner a copy of The Princess Bride, and Rob Reiner loved it and its father/son love story so much he turned it into a movie (with a grandfather and grandson). Three days before Carl’s death in 2020, he and Rob reenacted the final scene and “As you wish”

⚠️TYLENOL & AUTISM—RFK Jr and Trump are wrong—the largest & best study in the world in 2.5 MILLION KIDS—found no increased autism risk with acetaminophen (aka paracetamol, Tylenol) use by the mother during pregnancy. A crude unadjusted analysis found only a preliminary 5% risk, but once you adjust for family by matching using sibling controls (who didn’t get autism), the even tiny 5% risk vaporizes to 0% 📉. (Fun fact: I used to do drug safety epidemiology and have been whistleblower against big pharma when their drugs were dangerous—so I know a few things about drug safety data). Thread 🧵.

I thought someone had doctored this tweet, but apparently not.

SCOOP: Internal budget document reveals extent of Trump’s proposed health cuts. Our story. w ⁦@Carolynyjohnson⁩ ⁦@rachel_roubein⁩ ⁦@LaurenWeberHP⁩ ⁦@JoelAchenbach⁩ washingtonpost.com/health/2025/04…

Reports indicate that Spotify is currently down for many users ➡️outage.now/spotify Repost if it's also down for you #SpotifyDown #SpotifyOutage

@SpotifyCares You’ve been down for a while now…paid service credit?

Hi everyone! We're aware of issues affecting the Spotify app and website loading. The right team is on it and working on a fix. We'll keep you posted on our Community at: bit.ly/4jaSLBA

@seanwdoolan Congratulations, Sean!

Just wired our final investment out of Fund 1 💸 It's been a turbulent period in venture since '21. We did our best to stay disciplined & used the full 4 year investment period in V1. Lots of learnings which we'll share publicly in the coming months. V2 is now activated 👊

Pretty compelling how capable these tools have become in such a short period of time.

Here's the workflow of an MCP-powered Agentic RAG. It searches a vector database and falls back to web search if needed. Check the full breakdown (with code) below👇

After market tumult, Trump exempts smartphones from massive new tariffs arstechnica.com/tech-policy/20…

Just a reminder of one of the reasons Twitter (X) has become such a cesspool: theguardian.com/technology/202…

Scientists are sometimes wrong Pseudoscientists are always wrong I would stick with the scientists

Monty Python and the Holy Grail's budget of £200,000 was raised by 10 investors to contribute £20,000 each. 3 of those investors were Pink Floyd, Led Zeppelin, and Genesis.

RFK Jr saying "none of the 72 vaccines given to children have been tested against placebo " The reality : - Children are not given 72 vaccines - The ones they are given have been tested against placebo This serial liar is your HHS Secretary.

Unconscionable👇🏽

Ooh!! In a presentation today, JPM’s Michael Cembalest said major portions of Healthcare industry look pretty attractive when comparing price vs expected ROE on public stocks over next 12 months. Markets might get dislocated, credit conditions might change, but healthcare chugs along.

This hasn’t aged well.