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mudd
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mudd
@muddppnw
Inquiries: [email protected]
Chicago IL Katılım Eylül 2013
995 Takip Edilen321 Takipçiler
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Ella Emhoff, stepdaughter of former Vice President Kamala Harris, from 16 December last year:
"...I'm just sitting here crocheting, waiting for a friend, and I was just listening to this podcast that The Wall Street Journal put out about SSRIs and anti-anxiety meds and kind of the over-prescription of them in America.
"And it was making me think a lot because I've been on SSRIs for over a decade, almost fifteen years probably, and they were calling out the lack of research on long-term use of these things.
"They were calling out the lack of information that doctors give about coming off of these meds and kind of the psychological effects they can have.
"And it really got me thinking how little I've thought about that, naively, obviously.
"But I've noticed that every time I've gone off of it for a week or missed it or for whatever reason, like, it has been really hard for me, and I've had a really hard time.
"And I guess this is just something I was wondering if you guys have thought about or relate to or kind of consider when you're thinking about going on meds like that.
"Because I don't know if this is something that I feel like is being talked about enough because I feel like so many of us are on these meds, and this is, like, actually happening.
"Like, people get off of them, and they kind of break down, and it can be really bad. So yeah, I guess I just want your general thoughts."
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Your 8pm workout is shrinking your brain. It's also building belly fat and more than doubling your odds of dying in the next decade. Andrew Huberman is naming the mechanism.
Cortisol is supposed to peak when you wake up and crash by 11pm. Hard training after 7pm spikes it back up at the worst possible window. Four nights a week of evening workouts and the daily curve flattens. The morning peak softens. The evening trough inflates. The shape inverts.
A 2017 meta-analysis of 80 studies and 23,000 participants found that flatter cortisol curves predict higher mortality, more inflammation, worse cognition, and greater visceral fat. The hazard ratio for early death was 2.40. Total daily cortisol output didn't predict any of it. Curve shape carried the variance.
Whitehall II followed 4,000 British civil servants for six years and got the same answer. Flatter slope, hazard ratio 1.30 for all-cause death, 1.87 for cardiovascular death. Independent of every covariate they measured.
Robert Sapolsky's primate work shows what happens next. Subordinate baboons getting harassed daily show lower morning peaks and higher evening troughs than dominant baboons. The flattening comes first. Hippocampal atrophy follows. Cushing's patients show the same loss. PTSD veterans show the same. Three different pathways into chronic glucocorticoid exposure, one consistent brain effect, partially reversible when the curve gets restored.
There's another loop running underneath. Visceral belly fat manufactures cortisol locally. The enzyme is 11β-HSD1. It converts inactive cortisone to active cortisol inside the fat cell. Mice with adipose-specific overexpression of this enzyme develop visceral obesity, insulin resistance, and metabolic syndrome on completely normal blood cortisol. The systemic level looks fine. The local tissue is bathed in glucocorticoid signaling.
That's why "meditate to lower cortisol" doesn't shrink the belly. The belly is making its own.
What rebuilds the curve is cheap. Train hard before late afternoon. Keep the four hours before bed for walks and stretching. Get morning sunlight in the first hour after waking. Anchor sleep timing within a 30-minute window. Each one steepens the morning peak and deepens the evening trough. Total daily cortisol barely moves. The curve gets sharper.
Make the morning loud. Make the night quiet.

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@LukeDashjr @James32384509 Especially walking after consuming food will drastically improve numbers
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@James32384509 @muddppnw So I should just go back full on sugar and ignore the numbers?
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@LukeDashjr @James32384509 You should make sure all the “sweet things” you consume come from more natural sources (honey/maple syrup/fruit/organic cane sugar/coconut sugar), pair it with the right amount of proteins/fats and weight training/walking and the numbers will improve drastically
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@LukeDashjr Labwork numbers will improve. Weight training is also good because your muscles will use up glycogen in your blood
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@muddppnw I'm not concerned with actual symptoms, just numbers in labwork.
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@LukeDashjr Having some proteins/animal fats/fiber can lower the glycemic index so your insulin doesn’t spike as fast, and walking after meals can bring your insulin back down. Always a good idea to walk for 10 mins minimum or up to 1 mile after meals to bring insulin back down
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@muddppnw AFAIK all sugar is a problem for me. Fighting to prevent diabetes.
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@LukeDashjr That’s related to insulin sensitivity, lots of studies showing real, natural sugars like fruit, honey, maple syrup improves insulin sensitivity. Some of the keys become reducing drastic insulin spikes, and getting your insulin down faster after spikes.
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This is why I no longer speak at Bitcoin conferences.
These conferences are created and sponsored by those who want to centralize as much Bitcoin as possible into financial-industrial complex wrappers.
You resist by holding it in self-custody and boycotting all FIC wrappers, including conferences owned by Bitcoin treasury companies.
Heidi@blockchainchick
Are these the people you want "shaping Bitcoin's future"? The FBI Director. The Acting AG. The SEC Chair. The CFTC Chair. Bitcoin was literally invented to route around these people. Now they're the keynote speakers.
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>Be Cardinal Robert Sarah
>Born in a remote village in Guinea, raised by his devout catholic his parents and local missionaries
>Becomes an Archbishop at just 34 years old in the middle of a brutal Marxist dictatorship
>The dictator, Touré, literally puts him on a death list; Sarah doesn't run, and keeps preaching the Gospel
>Touré died unexpectedly of a heart attack in March 1984, just weeks before the planned executions
>Becomes one of the sharpest, most fearless defenders of traditional Catholic faith in the modern era and is made a Cardinal
>Looks at secularized West and warns us: "If Christianity disappears in Europe, the whole world is threatened."
>Writes absolute masterpieces like The Power of Silence
>Delivers banger quotes like: "The West has denied its Christian roots, a tree without root dies"
>"As a bishop, it is my duty to warn the West! The barbarians are already inside the city."
>Keeps telling europeans to have more babies
Unfathomably based


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El Salvador's President stated that the gangs they hunted and arrested in El Salvador were Satanists.
“There is a spiritual war and there is a physical war, if you win the spiritual war it will reflect into the physical. Our victory is because we won the spiritual war”
To the question on how he changed El Salvador he answered: “We pray”


Ada Lluch@AdaLluch
This is El Salvador at night. Fireworks, families walking around and kids playing. In Spain this is unthinkable of. Maybe locking up the criminals does work.
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Wait till you hear what hormonal birth control does to a woman’s brain. Among other things, it shrinks the ventromedial prefrontal cortex, a region involved in fear processing and emotional regulation.
MRI scans have shown this.
Quality Learing Center@qualitylearnc
Birth control should be illegal for this reason alone
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GENOCIDE? Algorithmically-curated dating apps have engineered a generational mismatch in romantic expectations that mirrors the worst dynamics of winner-take-all markets and positional goods inflation. Traditional courtship was bounded by geography, social circles, and time, forcing realistic self-assessment and holistic evaluation of partners across sustained interaction. Swipe-based platforms obliterated those constraints, collapsing all of human mate selection into a single ranked marketplace where hypergamy, the female preference for partners of equal or higher status, now operates without friction or limit. The data is not subtle: the top 20% of men on these platforms receive roughly 80% of female attention, a Gini-coefficient-level concentration of desire that has no precedent in the history of human courtship. Those men rationally respond to sudden abundance by abandoning commitment entirely, because the incentive to settle has been structurally demolished. At the same time, women who periodically access that top tier, regardless of how briefly or on what terms, permanently recalibrate their expectations upward, pricing themselves out of the realistic market of men who would have made them genuinely happy. Neither group is acting irrationally given the incentives presented to them, which is precisely what makes this so damaging: the apps have not corrupted individual character so much as they have poisoned the entire coordination mechanism through which generations of ordinary people found lasting partnership. The consequence is not a dating culture that is merely unsatisfying. It is one that is structurally incapable of producing the outcomes most of its participants actually want.
h/t @Degen_Poster

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