Pablo Ambram

Marc Andreessen just dropped ~105 mins on Lenny's Podcast covering AI, jobs, careers, and why everyone is panicking about the wrong thing. Just the clearest macro framework I've heard on where AI actually lands. My notes: 𝟭. 𝗔𝗜 𝗶𝘀 𝗮𝗿𝗿𝗶𝘃𝗶𝗻𝗴 𝗮𝘁 𝘁𝗵𝗲 𝗲𝘅𝗮𝗰𝘁 𝗺𝗼𝗺𝗲𝗻𝘁 𝗵𝘂𝗺𝗮𝗻𝗶𝘁𝘆 𝗻𝗲𝗲𝗱𝘀 𝗶𝘁. US productivity growth has been running at half the rate of the 1940-1970 era and a third the rate of 1870-1940. The global population is declining below replacement in dozens of countries, including China. Without AI, we would be panicking about economies shrinking from depopulation, not job loss. The timing is almost miraculous. This is what Andreessen means when he says the real boom has not started yet. We have been in a 50-year productivity drought, and most people do not even realize it. 𝟮. 𝗔𝗜 𝗶𝘀 𝘁𝗵𝗲 𝗽𝗵𝗶𝗹𝗼𝘀𝗼𝗽𝗵𝗲𝗿'𝘀 𝘀𝘁𝗼𝗻𝗲. Isaac Newton spent decades trying to transmute lead into gold and never succeeded. AI does something more powerful: it converts sand (silicon) into thought. The most common material in the world is the rarest output. This one metaphor reframes the entire AI conversation. You do not have a job loss problem. You have a philosopher's stone sitting on your desk that you are not using enough. 𝟯. 𝗔𝗜 𝗺𝗮𝗸𝗲𝘀 𝗴𝗼𝗼𝗱 𝗽𝗲𝗼𝗽𝗹𝗲 𝘃𝗲𝗿𝘆 𝗴𝗼𝗼𝗱, 𝗮𝗻𝗱 𝘃𝗲𝗿𝘆 𝗴𝗼𝗼𝗱 𝗽𝗲𝗼𝗽𝗹𝗲 𝘀𝗽𝗲𝗰𝘁𝗮𝗰𝘂𝗹𝗮𝗿𝗹𝘆 𝗴𝗿𝗲𝗮𝘁. The best coders right now are not reporting 2x productivity. They are reporting 10x. The gap between "pretty good with AI" and "elite with AI" is widening, not narrowing. This is the most important signal for career planning right now. If you are just using AI to do the same job slightly faster, you are leaving the real leverage on the table. 𝟰. 𝗧𝗵𝗲𝗿𝗲'𝘀 𝗮 𝗠𝗲𝘅𝗶𝗰𝗮𝗻 𝘀𝘁𝗮𝗻𝗱𝗼𝗳𝗳 𝗯𝗲𝘁𝘄𝗲𝗲𝗻 𝗣𝗠𝘀, 𝗲𝗻𝗴𝗶𝗻𝗲𝗲𝗿𝘀, 𝗮𝗻𝗱 𝗱𝗲𝘀𝗶𝗴𝗻𝗲𝗿𝘀. Every engineer now thinks they can be a PM and designer. Every PM thinks they can code and design. Every designer knows they can do both. And they are all correct, because AI enables each role to absorb the tasks of the other two. I have seen this firsthand in the investing world. The analyst who can build models and write narratives is 5x more valuable than someone who can do only one. The same convergence is happening in the product. 𝟱. 𝗙𝗼𝗿𝗴𝗲𝘁 𝗧-𝘀𝗵𝗮𝗽𝗲𝗱. 𝗕𝘂𝗶𝗹𝗱 𝗮𝗻 𝗘-𝘀𝗵𝗮𝗽𝗲𝗱 𝗰𝗮𝗿𝗲𝗲𝗿. Scott Adams could not have created Dilbert by being the world's best cartoonist or the world's best business mind. He needed both. The additive effect of two skills is more than double. Three skills are more than triple. Larry Summers puts it differently: don't be fungible. The person who can code, design, and ship a product is no longer a unicorn. They are the new baseline for "extremely valuable." If you are only one of those three things, you are increasingly replaceable. 𝟲. 𝗝𝗼𝗯𝘀 𝗮𝗿𝗲 𝗯𝘂𝗻𝗱𝗹𝗲𝘀 𝗼𝗳 𝘁𝗮𝘀𝗸𝘀. 𝗧𝗮𝘀𝗸𝘀 𝗰𝗵𝗮𝗻𝗴𝗲. 𝗝𝗼𝗯𝘀 𝗽𝗲𝗿𝘀𝗶𝘀𝘁. Executives never typed their own emails in the 1970s. Secretaries printed incoming emails and hand-delivered them. Both roles survived the transition, just with different task sets. The same will happen with AI and coding, PM work, and design. Everyone obsessing over "will my job disappear" is asking the wrong question. The right question is: which tasks in my job are about to rotate, and am I ready to pick up the new ones? 𝟳. 𝗔𝗜 𝗰𝗼𝗱𝗶𝗻𝗴 𝗶𝘀 𝗷𝘂𝘀𝘁 𝘁𝗵𝗲 𝗻𝗲𝘅𝘁 𝗮𝗯𝘀𝘁𝗿𝗮𝗰𝘁𝗶𝗼𝗻 𝗹𝗮𝘆𝗲𝗿. We went from human calculators to machine code to assembly to C to scripting languages. Each layer was dismissed by the previous generation. Each time, the new layer won, and total coding employment grew. AI coding is the same pattern, not a rupture. The Perl programmers of 2005, laughing at JavaScript, are the C programmers of 1995, laughing at scripting. History rhymes, and it always rewards the people who adopt the next abstraction first. 𝟴. 𝗔𝗜 𝘁𝘂𝘁𝗼𝗿𝗶𝗻𝗴 𝗱𝗲𝗺𝗼𝗰𝗿𝗮𝘁𝗶𝘇𝗲𝘀 𝗲𝗹𝗶𝘁𝗲 𝗲𝗱𝘂𝗰𝗮𝘁𝗶𝗼𝗻. One-on-one tutoring is the only method proven to move a student from the 50th to the 99th percentile (Bloom's two sigma effect). It used to require being born into royalty. Alexander the Great was tutored by Aristotle. Now, any kid with a phone can access the same quality of personalized instruction. This is the most under-discussed consequence of AI. Every parent reading this should be supplementing their kid's education with structured AI tutoring right now. Not next year. Now. 𝟵. 𝗣𝗲𝘁𝗲𝗿 𝗧𝗵𝗶𝗲𝗹 𝘄𝗮𝘀 𝗺𝗼𝗿𝗲 𝗿𝗶𝗴𝗵𝘁 𝘁𝗵𝗮𝗻 𝗔𝗻𝗱𝗿𝗲𝗲𝘀𝘀𝗲𝗻 𝗼𝗿𝗶𝗴𝗶𝗻𝗮𝗹𝗹𝘆 𝗮𝗱𝗺𝗶𝘁𝘁𝗲𝗱. Progress in bits masked stagnation in atoms. The built world is barely different from 50 years ago. Same bridges from the 1930s, same dams from the 1910s. Cartels, monopolies, unions, and regulations prevent the rate of change that people had 100 years ago. This is also why AI will not transform everything overnight. Institutional sclerosis is real. Healthcare alone could take a generation. If you are building in atoms, budget for a war of attrition, not a blitzkrieg. 𝟭𝟬. 𝗠𝗼𝗮𝘁𝘀 𝗶𝗻 𝗔𝗜 𝗮𝗿𝗲 𝗴𝗲𝗻𝘂𝗶𝗻𝗲𝗹𝘆 𝘂𝗻𝗸𝗻𝗼𝘄𝗻. Within a year of ChatGPT's launch, five American companies, five Chinese companies, and open-source all had roughly equivalent models. DeepSeek emerged from a hedge fund in China and basically replicated the American labs' work. The smartest AI insiders privately admit there aren't many real secrets among the big labs. This is the most honest take I have heard from a top-tier VC. No one knows if the value accrues to models, apps, or infrastructure. Anyone who tells you otherwise is selling you certainty they do not have. 𝟭𝟭. 𝗔𝗜 𝗜𝗤 𝘄𝗶𝗹𝗹 𝗯𝗹𝗼𝘄 𝗽𝗮𝘀𝘁 𝗵𝘂𝗺𝗮𝗻 𝗹𝗶𝗺𝗶𝘁𝘀. Human IQ caps around 160 because of biology. Current AI models test around 130-140. There is no theoretical ceiling stopping AI from reaching 200, 250, or 300. The concept of AGI as a "human equivalent" will be a footnote because AI will race past that threshold. This is the frame that makes the "will AI take my job" debate feel small. We are not building a replacement for human thought. We are building something that will be better than the best human thought has ever been. 𝟭𝟮. 𝗧𝗵𝗲 𝗯𝗲𝘀𝘁 𝗳𝗼𝘂𝗻𝗱𝗲𝗿𝘀 𝗮𝗿𝗲 𝗿𝗲𝘁𝗵𝗶𝗻𝗸𝗶𝗻𝗴 𝘄𝗵𝗮𝘁 𝗮 𝗰𝗼𝗺𝗽𝗮𝗻𝘆 𝗲𝘃𝗲𝗻 𝗶𝘀. Layer one: AI redefines products. Layer two: AI redefines jobs within companies. Layer three, which has not dropped yet: AI redefines the very concept of having a company. The holy grail is the one-person, billion-dollar outcome, and the best founders are chasing it. Satoshi did it with Bitcoin. Instagram and WhatsApp came close with tiny teams. The question is no longer if this is possible with software. The question is how many of these we will see in the next five years. AI is the philosopher's stone. The question is whether you pick it up. The full podcast is worth your time. Link in replies.

At Alpha School, we reverse this framing. Your 8-year-old experiences time at 5-8x your speed. A school day that feels "normal" to a 40-year-old parent is an eternity to a child. Every wasted hour in a classroom weighs 5-8x more to them than it does to you. Schools are built on the slow parent clock. ⌛️Alpha's TimeBack runs on the kid clock. ⏱️ 2 hours of focused AI learning. 2x the outcomes. The rest of the day belongs to them. The traditional school day is 6 hours because adults needed 6 hours. Your kid is paying for that - at a rate you literally cannot perceive.

The math on this project should mass-humble every AI lab on the planet. 1 cubic millimeter. One-millionth of a human brain. Harvard and Google spent 10 years mapping it. The imaging alone took 326 days. They sliced the tissue into 5,000 wafers each 30 nanometers thick, ran them through a $6 million electron microscope, then needed Google’s ML models to stitch the 3D reconstruction because no human team could process the output. The result: 57,000 cells, 150 million synapses, 230 millimeters of blood vessels, compressed into 1.4 petabytes of raw data. For context, 1.4 petabytes is roughly 1.4 million gigabytes. From a speck smaller than a grain of rice. Now scale that. The full human brain is one million times larger. Mapping the whole thing at this resolution would produce approximately 1.4 zettabytes of data. That’s roughly equal to all the data generated on Earth in a single year. The storage alone would cost an estimated $50 billion and require a 140-acre data center, which would make it the largest on the planet. And they found things textbooks don’t contain. One neuron had over 5,000 connection points. Some axons had coiled themselves into tight whorls for completely unknown reasons. Pairs of cell clusters grew in mirror images of each other. Jeff Lichtman, the Harvard lead, said there’s “a chasm between what we already know and what we need to know.” This is why the next step isn’t a human brain. It’s a mouse hippocampus, 10 cubic millimeters, over the next five years. Because even a mouse brain is 1,000x larger than what they just mapped, and the full mouse connectome is the proof of concept before anyone attempts the human one. We’re building AI systems that loosely mimic neural networks while still unable to fully read the wiring diagram of a single cubic millimeter of the thing we’re trying to imitate. The original is 1.4 petabytes per millionth of its volume. Every AI model on Earth fits in a fraction of that. The brain runs on 20 watts and fits in your skull. The data center required to merely describe one-millionth of it would span 140 acres.

For those unaware, SpaceX has already shifted focus to building a self-growing city on the Moon, as we can potentially achieve that in less than 10 years, whereas Mars would take 20+ years. The mission of SpaceX remains the same: extend consciousness and life as we know it to the stars. It is only possible to travel to Mars when the planets align every 26 months (six month trip time), whereas we can launch to the Moon every 10 days (2 day trip time). This means we can iterate much faster to complete a Moon city than a Mars city. That said, SpaceX will also strive to build a Mars city and begin doing so in about 5 to 7 years, but the overriding priority is securing the future of civilization and the Moon is faster.

I'm Boris and I created Claude Code. Lots of people have asked how I use Claude Code, so I wanted to show off my setup a bit. My setup might be surprisingly vanilla! Claude Code works great out of the box, so I personally don't customize it much. There is no one correct way to use Claude Code: we intentionally build it in a way that you can use it, customize it, and hack it however you like. Each person on the Claude Code team uses it very differently. So, here goes.

This paper shows a 2-brain design so a voice model can think and speak with near 0 delay. It scores 92.8% on a math speech test at 0 latency, and 82.5 on a dialogue test. Waiting for a full chain of thought slows replies, and mixing thinking and speaking in one model causes errors. So they split the work across 2 LLMs, a Formulation Brain that thinks and an Articulation Brain that talks. The Formulation Brain streams short thought chunks, and each new chunk paces the speaker to keep talking. The speaker reads the latest thought, all earlier thoughts, and its own past words, which keeps answers consistent. They train the speaker on partial thoughts with supervised fine tuning so it can speak before thinking finishes. Think First waits briefly for some thoughts then speaks, and Speak First starts at once but loses some arithmetic accuracy. Both modes beat single-model interleaving and match think-before-speak quality while cutting delay. ---- Paper – arxiv. org/abs/2510.09592 Paper Title: "Mind-Paced Speaking: A Dual-Brain Approach to Real-Time Reasoning in Spoken Language Models"

So @xAI 's @grok 4 really did hit 44.4% on HLE (Humanities Last Exam) 🤯 --- (HLE holds 2,500 expert-written questions spanning more than 100 subjects, including math, physics, computer science and humanities, and 14% of them mix text with images. The authors deliberately built in anti-gaming safeguards and hid a private question set so that simply memorising answers will not help a model.)

@VALLEOVA hola Osvaldo una consulta sabes si se esperan muchas demoras hoy 10 abril en el cruce (de chile hacia argentina), y quizás si sabes en qué horarios sería conveniente intentarlo. Gracias

@CFLosLibertador hola mañana 10 de abril hay operación normal del paso? el paro general en argentina afecta en algo?

@PasoCRMza hola. El paro del 10 de abril afectará la operación del paso, para ir de Chile hacia Argentina?

@defense_civil25 @DonnaPrissyrn1 @grok fact check this claim

🚨Update: Argentina is releasing all secret documents about Nazis in South American after 1945. Both CIA and FBI reports confirmed that Adolf Hitler escaped to Argentina after the War and lived until the late 1950s!

Amo a @JMilei

Misunderstanding about mentorship: When someone asks for help without already executing the basics, nobody wants to help that person. But when someone is clearly, visibly, consistently executing the basics, mentors WILLINGLY share information—because they see high potential.

"Our results reveal that whenever handwriting movements are included as a learning strategy, more of the brain gets stimulated, resulting in the formation of more complex neural network connectivity...typewriting do[es] not activate...networks the same way that handwriting does."

Best country ETF: 1-month: Argentina YTD: Argentina 1-year: Argentina 3-year: Argentina

Deregulation and reducing government spending leads to prosperity

I just found out that the ICC Prosecutor, Karim Khan, is an Ahmadiyya Muslim who focuses on missionary work to spread Islam and considers the Qur’an the ultimate and unalterable word of God. Explains a lot.

Difícilmente algún judío desconozca la historia del Caso Dreyfus, vergüenza de Francia, pero para quien no haya escuchado hablar del mismo, en este video subtitulado al español, el Primer Ministro de #Israel, Binyamin Netanyahu, hace un paralelismo entre el mismo y el actual juicio en La Haya. Imperdible 👌 Likes! 👍

Me resulta profundamente indignante la reciente decisión de la Corte Penal Internacional (CPI) respecto a Israel. No es la primera vez que este organismo, que se autoproclama defensor de la justicia global, demuestra una preocupante selectividad en sus prioridades. Mientras que atrocidades flagrantes en países como Irán, Siria, Corea del Norte y Venezuela pasan, en el mejor de los casos, a un segundo plano o, en el peor, son ignoradas por completo, la CPI parece ensañarse con Israel, el único país democrático y respetuoso de los derechos humanos en una región marcada por la tiranía y la violencia. Esta conducta no solo refleja un doble estándar intolerable, sino que pone en entredicho la legitimidad y los principios de una institución que debería servir como baluarte contra la injusticia, no como una herramienta al servicio de agendas políticas. En lugar de actuar con imparcialidad, la CPI se alinea con narrativas sesgadas, ignorando el contexto histórico y legal que sustenta las acciones de defensa de Israel frente a amenazas existenciales. El pasado me demuestra que esta hipocresía no es nueva. ¿Dónde estaba la CPI mientras millones eran masacrados en genocidios documentados? ¿Por qué los crímenes cometidos por dictaduras siguen sin ser investigados con el mismo fervor? Parece que, para algunos, el foco en Israel no es cuestión de justicia, sino de conveniencia política. No me sorprende, pero me indigna. Me enoja profundamente que se tergiverse la realidad y que se haga caso omiso a los verdaderos responsables de crímenes contra la humanidad, mientras se somete a juicio a quienes luchan por su supervivencia.

In under a year, @JMilei reduced Argentina's 🇦🇷 inflation from 25% to under 3% 👇 This is what happens when you aggressively and mercilessly cut public sector spending. @elonmusk will do the same to the US 🇺🇲 Keep up the great work @JMilei! _