patrickruch

@DrCatharineY I wish I could... but for a fraction of us get ready for insomnia !

Just a reminder that 2-3 cups of coffee a day has been associated with lower dementia risk and better cognitive function. So relax, enjoy your coffee, and your morning.

@florianederer A small tribute to direct democracy.

This has to be the dumbest policy proposal of all time.

@theepicmap The color cutoff is usually more interesting than the map itself :-)

What Time Does Europe Wake Up? ⏰🇪🇺 Credit: geodatarankings

@ItaiYanai "Friday, I'm in love" [The Cure]. We all know working late at night on Friday is meaningless !

Papers submitted on Tuesdays are more likely to be accepted by Nature whereas Wednesdays seem the most likely day to submit and secure acceptance to PLOS ONE. For Cell, Mondays and Tuesdays seem the best submission days in case of accepted papers. link.springer.com/article/10.100…

@Parisianaes1 Buy a subway ticket.

You arrive in Paris what's the first thing you do?

@OdedRechavi Understanding ? You mean like predicting some protein folding properties ?

Unpopular opinion: biologists are still the ones who understand biology best

@SpringerIME Ask a librarian #results-section" target="_blank" rel="nofollow noopener">biodiversitypmc.sibils.org/?query=Which%2… and you'll get CD19, CD19, CD19... CD20 !

How well do you know CAR-T therapy? With ASH 2025 approaching, we’re testing your clinical insight. Which antigen is most commonly targeted by CAR-T in LBCL?

@AdrianoAguzzi It could work but occasionally it does not and kill your code... so make a safe copy !

@LocasaleLab If "no one has seriously examined whether this track delivers genuine scientific or medical value", then your observations do sound very exaggerated !

The physician–scientist track (MD/PhD) in academic medical centers has become one of the great illusions of modern science - a path that promises to unite medicine and science but rarely fulfills either goal. Training stretches on for years as one person is expected to learn two professions at once, and in practice, they seldom master either. Many hold a token clinic for a few hours a week while running labs that produce derivative “translational” research — supposedly aimed at improving patient care. In reality, these efforts seldom advance either basic knowledge or clinical practice in a meaningful way. The personal rewards, however, are significant: MD/PhDs are paid far more than PhDs alone, face far less competition for faculty positions, are treated better by upper administration, and are freed from the full clinical responsibilities of practicing physicians. They also enjoy privileged access to administrative roles in medical centers, journals, and professional societies - positions that often pay handsomely. Yet almost no one has seriously examined whether this track delivers genuine scientific or medical value, or if it merely sustains another bureaucratic layer within an already bloated healthcare system. students-residents.aamc.org/md-phd-dual-de…

@ismaelminchala @ThePhDPlace Research has always been somehow risky... impact is more randomly distributed.

@ThePhDPlace He’s partially right. Unfortunately, academia these days is about “publishing” with no certainty in the impact of the research.

Elon Musk has called most PhDs “useless.” What do you think?

@sarvk Some people like to be thrilled for no particular reason.

Why some announce "arxiv" as their new publication with "I'm thrilled to announce our paper is published on arxiv" when is no linked peer-reviewed venue. Anyone can put anything on arxiv. It's a placeholder, and unless it goes through peer review, it should be treated that way.

@AdrianoAguzzi Congrats but that does not count... it's endogeneous money :-)

@BMuellerSN @AdrianoAguzzi It is nowhere worse than in medical faculties but maybe in Asian medical faculties...

@AdrianoAguzzi It may be worse in Germany than elsewhere, and worse in big collaborations. Sometimes it is connection with a delusion of excellence - nominally high productivity resulting from huge resources inherited from people's mentors.

@slavov_n Well, there may be many not yet known drivers....

No driver mutations could be identified in 181 tumors. The authors do not know why. Perhaps, it's an algorithmic failure. Perhaps, it reflects non genetic contributions to carcinogenesis. What do you think ?

@AdrianoAguzzi I am less optimist than you with the accumulating bad news (austerity measures in CH, NIH/NSF cuts, investments in guns all around) but surely chocolate is badly needed... even if those are actually macarons !

@GobeillJulien @deb_caucheteur @patrickruch 🗂️ The extracted data is accessible and searchable through the BiodiversityPMC platform, supporting enhanced literature discovery and curation workflows: biodiversitypmc.sibils.org

📚 Explore the latest from Bioinformatics Advances: "Unlocking the potential of PubMed Central Supplementary Data Files"   Full article available: doi.org/10.1093/bioadv… Authors include: @GobeillJulien, @deb_caucheteur, @patrickruch

@matthiassamwald Thank you for sharing ! The main issue with cybersecurity is that it is rarely evidence based, e.g. anti-spam filters... I fear the AI act is likely to inflate the burden on AI developers and users with no or little impact on security but sizeable loss of productivity !

Great summary thread of the code of practice and Safety & Security chapter

@AdrianoAguzzi @LaviniaMaddalu1 Interesting because for me, Milano is the place where I connect trains, a sort of Italian Bern :-)

Milan makes me hype! Up since 5.50am & my train accumulated a 2 hrs delay 😂 but happy to have managed to get to the ASMI before it closed (earlier this week, of course 😓 so I think I deserved this glorious GF pâtisserie 😋 Now waiting for some colleagues for Milanese apéro 🤓

@catgyoung Imho, boys too...

It’s true.