AAPS PharmSciTech

Co-crystal formation of the poorly water-soluble drug Mosapride Citrate was coupled with fused deposition modeling to 3D-print tablets in different configurations and thicknesses with a zero % infill. The co-crystal technique proved viable for solubility…lnkd.in/gYCFYi6f

A recently published paper explores the effects of composition and #manufacturing technology (#Kinetisol and spray drying) on the performance of #galeterone amorphous solid dispersions (#ASD). Compositionally equivalent formulations were assessed in an in…lnkd.in/gW8SNGME

This review article summarizes the current understanding of various dissolution models and data inputs in physiologically based biopharmaceutics models (PBBM) software and aims to discuss Authors: Sivacharan Kollipara, Adithya Karthik Bhattiprolu,…lnkd.in/ddzxXJcF

This #review article discusses the challenges in #ocular drug delivery due to the various barriers, such as the #precorneal, #corneal, and blood-corneal barriers. Additionally, the authors explore the different routes of administration for ocular drug del…lnkd.in/gMZN2fmz

Learn about PhysioCell®, a newly designed and constructed multi-compartment apparatus for non-compendial dissolution testing that simulates the dissolution of a drug throughout the gastrointestinal passage and its individual fragments, under both fasting…lnkd.in/gEbd37zD

Featured in our "Inhaled Drug Delivery of Biologics for Therapeutic and Vaccination" collection, the article reviews previous studies to support the feasibility of developing pMDI and DPI versions of The LNP-mRNA intramuscular #vaccines from #moderna (mR…lnkd.in/gbCSvzM5

Read the featured article from the Novel Advances in 3-D Printing Technology in Drug Delivery by Bhupendra Raj Giri and Mo Maniruzzaman. The article titled: "Fabrication of Sustained-Release Dosages Using Powder-Based Three-Dimensional (3D) Printing Techn…lnkd.in/gd-CXk8t

"Emulsions of emulsions" or "double emulsion" are systems in which an oil-in-water or a water-in-oil emulsion is dispersed in another liquid medium. You can learn more about these complex polydisperse systems providing stability to both proteins and small…lnkd.in/g29_G_-s

Discover the multifunctional role of Polyvinylpyrrolidone (PVP) in pharmaceutical formulations in this review paper. #polymers #drugdelivery @theaapsjournal, @BillTXCeutics, Daniel Davis, Ph.D., PharmD Read the full article here: rdcu.be/c0OG lnkd.in/dtgvM6pR

Published in our "Applications of Machine Learning and A.I. in Pharmaceutical Development and Technology" collection, this original research investigates the ability to combine Raman spectroscopy and machine learning to provide a s…lnkd.in/gFkfRaw7 lnkd.in/gG3AD3Vg

#newpublication by Dr. Hillary Mndlovu, @DeepPrads, Lisa du Toit, and Prof. Yahya Choonara at the University of the Witwatersrand developed an "in situ-forming bioactive delivery hydrogel with enhanced healing properties" Read more about the composition a…lnkd.in/gBtywBVV

Published in our "Advancements in Amorphous Solid Dispersions to Improve Bioavailability" collection, this original research investigates formulating and stabilizing an inherently unstable GFA Class II API in its amorphous form. #S…lnkd.in/dqR8sjiZ lnkd.in/dfrMj7g2

Published in our "Bioavailability" theme issue, authors Sagar Narala, Dinesh Nyavanandi, Abdullah Alzahrani, Suresh Bandari, Feng Zhang, and Michael Repka, investigate #cocrystals of #hydrochlorothiazide with various #coformers to…lnkd.in/ej_DxZqN lnkd.in/eEcHGp4B

Just published in our #theme issue" Advancements in Modified-release Oral #drugdelivery, " authors Wesam Mustafa, John Fletcher, Mouhamad Khoder, and Raid Alany investigate ternary solid dispersions to improve #mucoadhesive propert…lnkd.in/e4N85btw lnkd.in/eTdCTTba

Author Safa A. Damiati states “#bigdata in #pharmaceuticalsciences can be viewed as both a challenge and an opportunity”. In this review Safa A. Damiati summarized the past, present, and potential future impacts of #machinelearni…lnkd.in/eQHw-Zz3 lnkd.in/e_HN8cSU

Recently published in our #theme issue "Novel Advances in #3dprinting Printing Technology in #drugdelivery", authors Ludmila Alvim Gomes Pinho, Ana Luiza Lima, Livia Sa-barreto, Tais Gratieri, Guilherme Martins Gelfuso, Ricardo Ne…lnkd.in/gdjC4iVt lnkd.in/gh_taSxJ

Amorphous solid dispersions are an effective formulation technique to enhance the solubility and ultimately the bioavailability of poorly water-soluble drugs. In this original research, dolutegravir, a BCS Class II HIV drug, was fo…lnkd.in/gvdB9vHR lnkd.in/gHrKwrvH

Published in our theme issue " Pharmaceutical Thermal Processing - An Update" authors Jiaxiang Zhang, Rishi Thakkar, PhD, Vineet Kulkarni, Yu Zhang, Anqi Lu, and Mo Maniruzzaman investigate the influence of the fused deposition mod…lnkd.in/gQEYremq lnkd.in/gggzyPXr

AAPS PharmSciTech has seven topical collection themes that are open for submissions of #research, reviews, and commentaries!    2021 Topical Collection Themes Include: 1) Amorphous Binary and Ternary Solid Dispersions: Recent Innovations and Advancements…lnkd.in/gY9c88yk