Philipp Rescheneder

Human phased T2T (20 T2T chromosomes + 9 further scaffolds) assembly from standard ligation library + 10X PoreC on a single PromethION flowcell (the unreleased high output chemistry) #Nanoporeconf

@nanopore ‘s Phil James presenting on multiomic investigations and chromatin accessibility at #ASHG24

Incredible few days at the Nanopore Community Meeting. Thank you to @nanopore for inviting me to talk about our work looking into base-pair level chromatin accessibility @nickdlowens #nanoporeconf

Applications group presenting breadth of data available from a single @nanopore flowcell. #nanoporeconf

Dorado v0.8.0 #ncm24 release! - v5.0 DNA transformer model performance improved for A100/H100 via kernel fusing, quantisation and leveraging i8 tensor cores. - v5.1 RNA models with updated mod calling for m6A, pseU, and brand new calling of Inosine and m5C. - Improved dorado correct performance, stability and flexibility. - Introduces per-barcode configuration for poly(A) estimation with interrupted tails. #nanoporeconf github.com/nanoporetech/d…

Incredible presentation from Noah Bryan (a high school student!!!) on the detection of contaminated drinking water. And a clever rhyming title too! #nanoporeconf

👀 @nanopore #EPI2ME is really everywhere! Now even on your @Apple iPad. apps.apple.com/gb/app/epi2me-…

Published today in @Nature, we describe an approach for single-molecule protein reading on @nanopore arrays. By utilizing ClpX unfoldase to ratchet proteins through a CsgG nanopore, we achieved single-amino-acid sensitivity. nature.com/articles/s4158…

Edlib sequence aligner, github.com/Martinsos/edlib, has more than 500 starts now. Kudus to @MartinSosic, who did this for his master's thesis and has continued to improve it over the years!

A fantastic opportunity to keep breaking barriers on RNA biology

@colindaven @AW_NGS @krannich479 @keygene @nanopore @msikic Great! Let us know how it went!

Herro error corrected @keygene banana 🍌 @nanopore simplex reads versus duplex and HiFi data. Amazing work by @msikic and team. See you next week in London! #nanoporeconf #accuracy #pangenome #banana

@colindaven @AW_NGS @krannich479 @keygene @nanopore @msikic So far we also tried haploid honeybee and tetraploid coffee each using a single flowcell worth of data. Standard read length not ultra-long and no pore-c / parental data.

@colindaven @AW_NGS @krannich479 @keygene @nanopore @msikic Hi Colin, if you are interested we have HG002 data (2 ULK flowcells) available here: labs.epi2me.io/lc2024_t2t/ including instructions on how we ran error correction and subsequence T2T assembly.

@lh3lh3 @AlbertVilella @msikic @Dorylophile 's data after dark talk (which should be available on demand soon) has some more result for non-human and LSK assemblies.

@lh3lh3 @AlbertVilella @msikic HG002 data for testing is available here: labs.epi2me.io/lc2024_t2t/

A walkthrough of Clive's talk at London Calling 2024.

Open data set release for highly accurate @nanopore only telomere-to-telomere (T2T) assemblies #nanoporeconf labs.epi2me.io/lc2024_t2t/

Welcome to London ! At #nanoporeconf this year we will be live sequencing 10 Endangered and Critically Endangered Species to coincide with 10 years of London Calling. All supported through our ORG.one programme. Please come speak to us about it @nanopore

Median qscore 26.36, read n50 91 kb. Please have a look and let us know how you get on

Check out the data from this experimental extremely high-accuracy, ultra-long sequencing kit here labs.epi2me.io/gm24385_ncm23_… The numbers from this tech update are incredible.