pines

How does TMS — a treatment for depression — reshape dysfunctional brain circuits? In our new Cell paper, we identify a cell type-specific prefrontal mechanism linking accelerated iTBS to antidepressant-like behavioral effects and circuit plasticity. cell.com/cell/fulltext/…

What are the neural correlates of human behavior? Much research has approached versions of this question between individuals but not within individuals. Are results from these 2 approaches similar? No! In over 4000 individuals, the neural correlates of cognitive control diverged between vs. within individuals -- a case of non-ergodicity and Simpson’s paradox. We think that non-ergodicity may be an important principle in human neuroscience. [1/12]

Diffusion MRI (dMRI) is a powerful tool to study white matter maturation. In our new preprint, we process and distribute a new resource of >24,000 ABCD dMRI scans using open source tools! We then evaluate how methods shape inferences about development. 🔗 bit.ly/3QMLG0K

Our first work from my PhD period: biorxiv.org/content/10.648… In this study, we propose a computational model and theoretical framework for neural dynamics. This is only a starting point, but it also reflects our broader academic ambition.

We think of white matter as highways of the brain. But when we followed development along those highways, we were surprised. The journey is more complex than we thought. My PhD paper, “Two Axes of White Matter Development”, is now out in @NatureComms!🧠 🔗bit.ly/wm2axes

My second first author paper of graduate school - Sex differences in response to violence: role of salience network expansion and connectivity on depression - is now published in Translational Psychiatry! rdcu.be/eLYg6

Emotions are core to the human experience 😆😮🙂😊☹️😠😳😑. But how do they arise? Our brain-wide ⚡recordings in humans and mice reveal some answers @ScienceMagazine. A big team effort and debut paper from @Stanford's new Human Neural Circuitry program. bit.ly/4dEyX7Z

Congrats Paula!!

The electric fields given off by TMS are super distributed: this is a great one for piecing apart the implications of that spread for individual treatment outcomes. Congrats Divya!

Breathing isn’t just for life—it’s a brain pacemaker! This excellent review reveals how each breath sends sensory waves that globally synchronize neural networks - with implications for "functional connectivity". Congrats to the authors! 👉 doi.org/10.1038/s41583…

‼️PhD Position now available in my lab‼️ Do you like: * Neurodegenerative disease? * Neuroimaging and/or multi-omics? * AI and data-driven life science? Want to work with @RikOssenkoppele Alexandra Young and Laura Wisse? Apply here: lu.varbi.com/what:job/jobID… Please rt/share 🙏

Seems relevant to all the white matter targets popping up in brain stim. Not just a highway anymore!

Thrilled to announce our study, “Connectional Axis of Individual Functional Variability: Patterns, Structural Correlates, and Relevance for Development and Cognition,” now published in @PNASNews pnas.org/doi/abs/10.107…

Our preprint detailing our novel approach to identifying personalized neuromodulation targets to treat severe, refractory OCD using brain mapping is now out on MedRxiv. Here, we describe our first SEEG-guided DBS case for OCD at UCSF: medrxiv.org/cgi/content/sh…

(1/17) Now out on bioRxiv‼️Reproducible Brain Charts: An open data resource for mapping brain development and its associations with mental health | doi.org/10.1101/2025.0… Funded by @NIMHgov

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Our work linking GWAS and pharmacological treatments in psychiatric disorders is now in JAMA Psychiatry jamanetwork.com/journals/jamap… 🧬💊🎯 Big thanks to @bendfulcher @AFornito @BellgroveMark 🧵👇

Now out in @NatMentHealth 🥳🥳🥳 this is the 2nd study of my dissertation with Carrie Bearden, co-led with @dehughes14 💫💫nature.com/articles/s4422…

Topography of putative bidirectional interaction between hippocampal sharp wave ripples and neocortical slow oscillations biorxiv.org/cgi/content/sh… #biorxiv_neursci

✨New Preprint!✨ Sex differences in psychiatric disorders often show up in adolescence as disparities in prevalence, symptoms, and treatment outcomes. We aimed to better understand sex diffs in brain organization that might lead to these disparities! t.ly/x6oxC 🧵⬇️