GlobalPneumoSeq

Have you read about our #GPS_project study on how genomic surveillance can have real impact on improving #pneumococcal vaccines? If not, perhaps put it on your reading list now! thelancet.com/journals/lanmi…

Key findings: 1. GPSC10-24F and GPSC12-3 have significantly increased after PCV13 2. AMR reduced after PCV rolled out Collaboration between the Center for Infectious Diseases Research at the American University of Beirut and the GPS Project at the @sangerinstitute

GPS funded placement awardee Dr Fatima Dakroub has published her finding in Microbial Genomics, highlighting the replacement of PCV13 with PCV10 (Pneumosil) will reduce the coverage of circulating serotypes in Lebanon. pmc.ncbi.nlm.nih.gov/articles/PMC12…

The science of GBS vaccines is advancing rapidly, but how do we implement them? In Plenary 4, we look at the evidence and economics behind the rollout. #ISSAD2026 #GBS #GlobalHealth

Got S. pneumoniae FASTQ read files? 🧬 Once you have run the GPS Pipeline, how do you visualise the results? 👁️ Check out our new tutorial on moving from FASTQ to interactive phylogenetics in @MyMicroreact ! 🌲 Step-by-step guide: github.com/GlobalPneumoSe…

In this festive season, we wish everyone a joyful and lovely holiday to spend with your loved ones ❤️

Dr Dorota Jamrozy (Wellcome Sanger Institute) is joining #ISSAD2026! As scientific lead for the Juno Study, she'll present critical data on the genetics & evolution of Group B Streptococcus (GBS). From Evidence to Action. Register: issad.org/registration #ISSAD2026 #GBS

A great collaboration between @nicd_sa and @sangerinstitute, as part of the #GPS_project

GPSC5 (23F->35B) also observed in children under five in South Africa 🇿🇦 nature.com/articles/s4146…

[🚨new paper 🚨] @nicd_sa team reported the 16-year adult IPD cases before and after PCV in South Africa 🇿🇦 , showing 1. Significant decrease in vaccine serotype lineages 2. significant increases in GPSC26-12F 3. GPSC5 (23F->35B) 6. GPSC9 (14->15A) microbiologyresearch.org/content/journa…

Antibiotic resistance is a global crisis. Our study reveals how Streptococcus pneumoniae acquires macrolide resistance during colonization—driven by bacterial clustering, inside and outside the host, and key metabolic pathways. New targets to slow AMR. #fig0010" target="_blank" rel="nofollow noopener">sciencedirect.com/science/articl…

[🚨Data release🚨] The #GPS_project database Monocle is now having 40k pneumococcal genomes and detailed metadata ! Thanks @HarryHung at @sangerinstitute and Simran Utreja at CDC to put them together! data-viewer.monocle.sanger.ac.uk/project/gps

Performing GPSC/lineage-specific analysis? We have made assemblies and annotations for 73 common GPSCs more accessible than ever: github.com/GlobalPneumoSe… Annotations were generated using Bakta v1.11.4 with the v6.0 full database.

This paper is out on Microbial Genomics @MicrobioSoc ! microbiologyresearch.org/content/journa…

It’s such a pleasure to see that #GPS_project 🩻funded by @gatesfoundation has been featured in this AMR article by @sangerinstitute , showing our global efforts on evaluating AMR after vaccine 💉 rollout. sangerinstitute.blog/2025/10/01/ten…

This work is the combined effort of @HarryHung @kumarnaren13 Victoria Dyster @stephlo_lo @StephenBentley5 at @sangerinstitute; Corin Yeats at @TheCGPS; Benjamin Metcalf, Yuan Li, Paulina Hawkins, Lesley McGee at @CDCgov; and funded by @gatesfoundation

Try it out: 📂 Code: github.com/GlobalPneumoSe… ✅ Features: QC, serotyping, MLST, GPSC assignment, AMR prediction. 🌍 Built for global use: from powerful HPC clusters to nimble laptops.

🦠🧪🧬 Excited to share that our GPS Pipeline, the portable and scalable genomic pipeline for Streptococcus pneumoniae surveillance, is now published in @NatureComms 🔗 nature.com/articles/s4146… #GPS_project