PREdiCCt retweetledi
@VIPStudy1 Had your 3rd vaccine?😀. Please let your local site know 🙏🙏🙏
Edinburgh, Scotland 🇬🇧 English
PREdiCCt
1K posts
PREdiCCt
@predicct
A #bigdata study looking to increase understanding of how #environment, lifestyle, #diet, genetics & the #microbiome influence flare in #Crohn's disease & #UC.
Recruiting now at 42 UK sites! Katılım Kasım 2015
207 Takip Edilen2.1K Takipçiler
PREdiCCt retweetledi
Hey folks 👋
Do you want to know more about @clarityibd?
✅how/why it started? The latest results and what they mean?
Then do watch the talk by Dr Tariq Ahmad (@clarityibd very own 🎩🌟)
Annual General Meeting 2021 | Crohn's & Colitis UK shar.es/aWCAtR
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PREdiCCt retweetledi
The environmental pressures on a modern gut are undoubtedly different from those of our hunter-gatherer ancestors. The microbiomes would reflect this.
What does this mean for us today?
The paleo vs plant-based debate shows this is complex.
More data would help!
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PREdiCCt retweetledi
We now have clear guidance from JCVI on those patients eligible for a 3rd primary dose of COVID vaccine.
This includes IBD patients on infliximab, adalimumab, ustekinumab, tofacitinib, prednisolone and some on high-dose aza/mp/mtx.
Details here & below
gov.uk/government/pub…
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PREdiCCt retweetledi
The impact of Crohn's disease and UC on a person's life can be devastating.
With 1 in 125 of the population living with #IBD it is important we realise what they might be going through.
It isn't just physical; here 👇 are just some of the ways IBD affects people.
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PREdiCCt retweetledi
Meta-analysis of studies of nutrient intake in #InflammatoryBowelDisease #IBD #Crohns #Colitis
Low intake of fibre is strongest and most consistent finding
How can we help people with IBD to increase #fibre intake?
Full paper @HoldGeorgina @APandT 👉🏽 onlinelibrary.wiley.com/doi/10.1111/ap…
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PREdiCCt retweetledi
We are developing and testing increasingly targeted therapies for Crohn's disease & ulcerative colitis.
New molecules will hopefully bring increased efficacy with minimal / no safety issues.
Not all will make it to market - some have already failed.
But there is more to come.
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PREdiCCt retweetledi
Prevention and cure are big words with a big impact.
But are they possible in IBD?
I've mapped out some of the key steps to move us to preventing IBD.
Data are coming ...
#ship30for30
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PREdiCCt retweetledi
Day 13 of #ship30for30 paging all @predicct participants and requesting you complete the final follow-up questionnaire please
twitter.com/charlie_lees/s…
Charlie Lees@charlie_lees
I have a big favour to ask. Have you taken part in the @PREdiCCt study? Then we need your help. Please log into the PREdiCCt portal and complete the final questionniare. Here is why this is so important and a big thank you. @crohnscolitisUK @crohnscolitisc3
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PREdiCCt retweetledi
What happens when the delicate balance between environment, genes and microbiota is disrupted?
Inflammatory bowel disease (IBD) can develop
Crohn's disease and ulcerative colitis now affect 1 in 125 people in the developed world.
The numbers are going up fast elsewhere.
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PREdiCCt retweetledi
I have a big favour to ask.
Have you taken part in the @PREdiCCt study? Then we need your help.
Please log into the PREdiCCt portal and complete the final questionniare.
Here is why this is so important and a big thank you.
@crohnscolitisUK @crohnscolitisc3
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PREdiCCt retweetledi
Multiple environmental factors impact the gut in health and inflammatory bowel disease:
• diet
• sleep
• travel
• stress
• surgery
• hygiene
• exercise
• smoking
• geography
• emulsifiers
• medications
Important to take a HOLISTIC approach to health and disease.
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PREdiCCt retweetledi
These data were presented as an e-poster at the DDW and ECCO meetings this year by our IBD clinical fellow turned consultant @SSiakavellas
Here is the full poster [👇]
@predicct @UoE_CGEM @LauranneDerikx
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PREdiCCt retweetledi
What causes disease flares in IBD?
We asked the 2639 participants of the @PREdiCCt study in their baseline questionnaire.
1946 replied - these were their top responses
• stress (69.8%)
• dietary changes (46.8%)
• alcohol (19%)
• sleep disturbance (17%)
#ship30for30
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PREdiCCt retweetledi
I've started to think about life for our patients post-pandemic.
We face many challenges but I'm optimistic.
Advances in drug development, genomics, digital health, AI & more.
This is the start of a new series on Innovations in IBD & the story of the innovators.
#ship30for30
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PREdiCCt retweetledi
We asked 1946 patients with Crohn's and UC in remission about fatigue: here's what we found.
40% of patients were fatigued >50% of the time.
Factors associated with fatigue
• depression & anxiety
• clinical disease activity
• female sex and higher BMI
@PREdiCCt #Ship30for30
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PREdiCCt retweetledi
@DCAnonBro Studies like this are happening - @predicct for example.
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PREdiCCt retweetledi
Yes Edinburgh is open ✅
VIP Study@VIPStudy1
☀️☀️@VIPStudy1 is fully open at all sites ➡️ vipstudy.uk 📢IBD and no IBD folk ➡️ covid vaccination study. ✅Have you had 2 doses of 💉 < 92 days ago? ✅IBD patients 👉 on only: Vedo IFX Aza/MP Tofu Uste + IFX + Aza/MP Check out 👉redcap.exe.nhs.uk/surveys/?s=DDE…
Edinburgh, Scotland 🇬🇧 English