Dr. Aditi Singh

Now recruiting! @BradMcG04 of @DanaFarber leads @ALLIANCE_org A032201 (STRIKE) to see if adding the anti-cancer drug tivozanib to the standard treatment of immunotherapy after surgery helps patients with high-risk renal cell cancer. Learn more: bit.ly/Alliance-A0322… #NCI

@AHazimMD @KLeventakos @aadel_chaudhuri Best of Luck

It’s a great feeling to submit my first grant. I’m incredibly thankful to my mentors for their guidance and support. @KLeventakos @aadel_chaudhuri

Carbone et al. showed that mesothelioma in patients with the BAP1+/- mutation is biologically, histologically, and clinically distinct, requiring a tailored treatment approach. Read more in this month's JTO: bit.ly/3K5KSBj

A082101 led @AMansfieldMD of @MayoClinic evaluates the safety & effectiveness of immunotherapy before surgery for #mesothelioma. #Immunotherapy helps the body’s immune system fight cancer. Learn more: bit.ly/Alliance-A0821… @thenci #nctn

@BalazsHalmosMD 😅

Press release!!! And just as a reminder- benefit of io/vegf bispecifics believed to come from “cooperative” binding via VEGF dimers leading to more avid inhibition of pd1/pd-l1 as well as vegf/vegfr axis And with all the excitement- there is now a bit of a queue to get to the top of the IO Mt Everest Summit!

@BalazsHalmosMD Yay

Merck shakes the HN oncology Earth! KN689 results leading to FDA filing- as compared to disappointing adjuvant IO results ala Javelin etc, perioperative pembro for resectable LA HNSCC yielding improved EFS and increased mPR rates- further expanding the horizons of neoadjuvant therapy!

Does immunotherapy in #SCLC delay brain metastases? Retrospective report @LungCaJournal on 550 pts show pts treated with atezolizumab + carbo/etop longer time to intracranial progression: 24.4 vs 14.3m and if no PCI: 27.2 vs 15.2m. Improved PFS and OS. lungcancerjournal.info/article/S0169-…

Report on NGS in squamous NSCLC @LungCaJournal from Dr. @Joshua_Reuss et al. Detected actionable genomic alterations in 22.2% of patients with squamous NSCLC and no history of smoking including #EGFR and #MET. In those with prior smoking, AGAs in 2.4%. lungcancerjournal.info/article/S0169-…

Hot off the press, Alliance CABINET! Cabozantinib in previously treated (93% had SSA, 60% had PRRT, 72% had everolimus) advanced NETs. The primary endpoint, PFS, was significantly better in the cabo arm than placebo. @ALLIANCE_org nejm.org/doi/full/10.10…

Do we need to do cardiac monitoring for all patients on Osimertinib? Congrats to Dr Francisco Martinez, recent KPSF fellowship graduate’s poster at #wclc2024 Bottom line: >800 pts, 3700 ECHOs, only 10 Osi HF events Higher in a fib, CHF hx pts @KPDOR @Rayliukpsfo @LoriSakoda

@DrSteveMartin @ececalidaylan Next Stop: Minneapolis! Last day to attend MN State Fair as well. You are missing on cheese curds and deep fried ranch.

Mentorship 101: Important to check on your mentees even after they start a new job- like Eçe at Wash U- even if one has to drive 1000+ miles for it!😉 I took the effort to introduce her to new skills, like eating alligator tacos.. Great to see you taking a fantastic start, Eçe!

🫁 Lung Cancer - ICIs data 🫁 🌟 Summary of 5-year (long follow-up) data 🌟 NSCLC (NSQ & SQ) #Immunotherapy #Lungcancer #longfollowup #LCSM

Make Way for the Celtics. 💚

@KLeventakos Are you finally spilling the “olives” about your fitness?

Diets | New England Journal of Medicine nejm.org/doi/full/10.10… Excellent paper on diets. Robust evidence for Mediterranean diet benefits🫒

EGFR mutants are not a monolithic entity. In fact EGFR mutational status is heterogeneous and EGFR mutated cancers can be Dr Jekyll or Mr Hyde #AACR24 @marinagarassino

#ASCO24 environmental signatures in non-smoking lung cancer in Asia

Management of pregnancy w/ 🫁ca 🚫 1st trimester ✅Dose according to actual body weight ✅Maintain dose intensity 🚫increase/decrease the dose 🚫chemotherapy @ 35-37 of gestation ✅minimum 3-week interval between the last cycle➡️delivery 🚫avoid IO in 2/3 trim 👀🫁-@matteolambe @asco #ASCO24 #lcsm

Can always trust @jennifermarksmd to summarize a lung session if you happen to miss it. #ASCO24