Angel Gonzalez-Valero

Really exciting research coming out of @christhechang lab! An oxidative cyclization reaction of the indole moiety of Trp for chemoselective bioconjugation to the rarest amino acid! Great work led by postdoc @Shaw_XXie and former Toste postdoc Patrick Moon! nature.com/articles/s4158…

Really fantastic work led by my friend and benchmate @VanhaN_Pham and alumnus @chembiokevin! This study unveils how endogenously produced formaldehyde can chemically modulate distinct proteins leading to changes in cellular SAM pools and epigenetic regulation.

Angel Gonzalez-Valero presenting at the Harvard Chemistry Future Leaders Symposium #chemtwitter @UCB_Chemistry

Very grateful to have been able to participate with NODE in the creation of this new space!!✨

Berkeley crew at #2023BioorganicGRC!

Nanostructured gold can be totally deactivated in some oxidation reactions used in therapy when thiols are present... except if you can combine it with Copper-Iron particles! Check our last contribution! @INMAdivulga @unizar #mmc1" target="_blank" rel="nofollow noopener">sciencedirect.com/science/articl…

Excited to share our work on developing a library of covalent methionine ligands and applying this to identify an allosteric inhibitor to cancer-driver CDK4! Huge thanks to the whole team and shoutout to @audreyglynn & @christhechang for your support! pubs.acs.org/doi/full/10.10…

Excited about this work led by @audreyglynn @puroAGV @UCB_Chemistry with @Toste_Group and @NovartisScience where we develop a methionine-directed covalent fragment library and identify a CDK4 inhibitor by targeting a new redox/phosphorylation crosstalk pathway