realArnoldLab

178 posts

realArnoldLab

realArnoldLab

@realArnoldLab

Freiburg, Germany Katılım Eylül 2019
193 Takip Edilen239 Takipçiler
realArnoldLab
realArnoldLab@realArnoldLab·
Happy to share latest work from the Lab by lead author Chiara Schröder, out in DevCell: global enhancer remodeling giving competence for mesoderm/endoderm differentiation by co-workers EOMES and SWI/SNF. Transcription comes later! So, EOMES is not a TF, but a chromatin regulator!
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Ina Sonnen
Ina Sonnen@SonnenKatharina·
I am very proud of Yasmine from the lab for winning a poster prize at the #GfE2024 organized by the German and Dutch societies for developmental biology for her work on Hes1 dynamics in the embryonic tail. Congratulations!
GfE@GfEeV

Here are the five poster prize winners of the #GfE2024 in alphabetic order: Vanessa Disela, Yasmine el Azhar, Olga Jarosinska, Laura Klink, Barbara Ohlebusch. Congratulations to you!

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Alfonso Martinez Arias
Alfonso Martinez Arias@AMartinezArias·
WRT the recent interest in TbxT, aka #Brachyury, & all kind of tails, nice historical perspective on this most iconic gene in the history of #DevBio shorturl.at/lEK57. Below, heroes of Brachyury (Fig.2 in ref ) + B. Herrmann, who cloned the gene &, of course, the T/+ mouse
Alfonso Martinez Arias tweet media
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realArnoldLab
realArnoldLab@realArnoldLab·
Happy to share Tanja‘s new preprint: looking@transcription from quite a different angle: basal TFIID, IDRs and splicing.
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realArnoldLab
realArnoldLab@realArnoldLab·
@bxv_dev Hurray Geoffrey, great to see this being online! Can’t wait to read it!
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bxv_dev
bxv_dev@bxv_dev·
TBX3 is essential to establish the posterior boundary of anterior genes and up-regulate posterior genes with HAND2 during onset of limb bud development dlvr.it/T2FCW2
bxv_dev tweet media
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Tschopp Lab
Tschopp Lab@TschoppLab·
We provide further evidence for the downregulation of NOGGIN by pSMAD, as predicted by our simulations, and detail the early antiphasic behavior of GDF5 and pSMAD that result from a self-organizing Turing system that drives joint initiation in developing digits of amniotes... 2/3
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Rita Strack
Rita Strack@rita_strack·
Very curious if anyone guessed this 😁 Our 2023 Method of the Year is methods for modeling development (aka embryoids)!!!! Some amazing things happening in this space enabling our understanding of the earliest stages of embryogenesis and beyond. Please enjoy the issue!
Nature Methods@naturemethods

It's that time of year!! 🎉We are so excited to announce our 2023 pick for Nature Methods' Method of the Year: methods for modeling development. Read the Editorial to find out why we chose this as our pick. #moty2023 nature.com/articles/s4159…

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Asifa Akhtar
Asifa Akhtar@AsifaAkhtar1·
Ever considered that the loss of your favorite epigenetic factor might impact gene expression in an allele-specific manner? Our new study shows allele-specific gene regulation by the chromatin regulator MSL2.nature.com/articles/s4158…
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MPI of Immunobiology & Epigenetics
🚨 The lab of @AsifaAkhtar1 uncovered in @nature a mechanism that safeguards the biallelic expression of haploinsufficient genes. The epigenetic regulator MSL2 acts as an “anti-monoallelic” factor that maintains biallelic gene dosage. This discovery not only reveals a communication system between parental alleles but also points to potential therapeutic strategies for diseases associated with haploinsufficient genes. Congratulations to @sun_yidan, Meike Wiese & @raedhmadi 🥳 Press release: ie-freiburg.mpg.de/5808498/news_p… Paper: nature.com/articles/s4158…
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kuba sędziński
kuba sędziński@ksedzinski·
Super happy that our#MechanoFate🐸 project received #ERCCoG funding! Huge thanks to my incredible team, friends, and colleagues for their invaluable help, as well as to the reviewers, and the panel. Exciting time ahead! @UCPH_health @UCPH_reNEW @reNEW_Global
reNEW@reNEW_Global

Congratulations @ksedzinski from @novonordiskfond Center for #stemcellmedicine, at @UCPH_health for being awarded an @ERC_Research grant to explore how mechanical forces coordinate the development of mucociliary epithelium > shorturl.at/lqD18

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