Rogier J. Nell

Very happy and proud to share our latest publication: A novel digital PCR-based method to quantify (switched) B cells reveals the extent of allelic involvement in different recombination processes in the IGH locus. doi.org/10.1016/j.moli… #bcells #digitalpcr

So excited to share our work with @lane_andy on Y chromosome loss in cancer! authors.elsevier.com/a/1hKLcL7PXmcx-

@IreneChristodou @Nature_NPJ @ChildrensLA Congratulations Eirini!

Combined low-pass whole genome and targeted sequencing in liquid biopsies for pediatric solid tumors nature.com/articles/s4169… @Nature_NPJ @ChildrensLA

Onderzoeker @harlaarniels is genomineerd voor de Hugo van Poelgeestprijs. Hij werkt aan de ontwikkeling van nieuwe menselijke hartmodellen ter vervanging van proefdieren bij onderzoek naar hartaandoeningen. Bekijk zijn video bit.ly/3CI6jRm & stem op Niels! @Proefdiervrij

Oogspecialist prof Martine Jager ⁦@LUMC_Leiden⁩ koninklijk onderscheiden! Als iemand dat verdient, dan is zij het wel. Echt indrukwekkend wat zij allemaal heeft gedaan. Zie ⁦@Sleutelstad⁩ 👇🏼👇🏼 sleutelstad.nl/2022/06/20/oog…

Lex van der Eb geëerd in Leiden: Emeritus hoogleraar is uitvinder belangrijke vaccinatietechnologie dlvr.it/SSNFyY

Thrilled to present our latest research 'Vitreous fluid as a new liquid biopsy for primary uveal melanoma' during the ISOO congress in hometown Leiden!

Exciting news for the European OM community! In addition to @US_FDA approval in January for ocular melanoma patients in the US, Kimmtrak has now been approved by the European Commission to treat patients with unresectable or metastatic uveal melanoma. buff.ly/36YBawT

LUMC-artsen hebben een bloedtest gemaakt die aantoont of iemand huidlymfomen, een vorm van #huidkanker, heeft. Dit is belangrijk omdat de symptomen vaak worden gemist. Hun volgende doel is om de test in heel Europa beschikbaar te maken ➡️bit.ly/3rpDS62 #wereldkankerdag

Limitations and opportunities of technologies for the analysis of cell-free DNA in cancer diagnostics rdcu.be/cF5HJ

Congratulations @harlaarniels on this amazing work: "Conditional immortalization of human atrial myocytes for the generation of in vitro models of atrial fibrillation", just published in Nature Biomedical Engineering. nature.com/articles/s4155…

Why would αβ T cell clones selectively express a γδTCR chain? #scRNAseq #TCR #singlecell

Very proud to share our latest work: Accurate quantification of T cells in copy number stable and unstable DNA samples using multiplex digital PCR jmdjournal.org/article/S1525-…

Amazing application of our DNA-based methodology to quantify T cells using #digitalPCR (see jmdjournal.org/article/S1525-…) #HIV

Nieuwe Melanoom Info Webinars op zaterdag 26 juni open voor inschrijving! Zie voor programma en aanmelding: 14.00-15.30 huidmelanoom ->bit.ly/2RKH1hP 16.00-17.30 oogmelanoom -> bit.ly/2SrxxIH #stichtingmelanoom #melanoominfowebinar #melanoom #oogmelanoom

B cells in melanoma might not always be a positive predictive biomarker, we actually found the opposite in D/T-treated pts Role of Tumor-Infiltrating B Cells in Clinical Outcome of Patients with Melanoma Treated With Dabrafenib Plus Trametinib clincancerres.aacrjournals.org/content/early/…

The Cancer Genome Atlas is pushing the boundaries of #CancerResearch. Visit our website to discover how the Atlas has made an impact through researchers who have used the data to make a difference in the lives of people with cancer. go.usa.gov/xHzK8 #NothingWillStopUs

Onze oogartsen dr. Irene Notting en dr. Yanny Cheng slaagden erin beide lenzen in de ogen van chimpansee Fiffy te vervangen. Lees meer over deze bijzondere ingreep ➡ bit.ly/3yHjJtM Foto: Marina Marinkovic

More applications of our method and some exciting results coming soon! Thanks to Wim Zoutman and Pieter van der Velden @LUMC_Leiden for this wonderful collaboration! (5/5) #digitalPCR

By measuring the total amount of DNA and its origin (T cells or B cells), our approach is capable of differentiating between a benign uveitis and malignant lymphoma (see image). I will virtually present this work at @ARVOinfo's Bench to Bedside Meeting (May 20-21). (4/5)

I am thrilled to share our recent work, now published as a patent application patentscope.wipo.int/search/en/deta…. We developed a digital PCR-based approach to quantify T cells, B cells and class-switched B cells in benign and malignant DNA samples. (1/5)