Rumi Habib

A new Science #Immunology study in macaques identifies the V2 apex region of the #HIV envelope as the most common target for broadly neutralizing antibodies (#bNAbs) and finds that B cell priming is the bottleneck to bNAb induction. @rumihabib scim.ag/4aMulwz

Two new animal studies show that B cell priming is key to induce broadly neutralizing antibodies (#bNAbs) against #HIV and demonstrate that a single immunization that targets bNAb precursors can induce potent neutralization. 📃: scim.ag/4aMulwz 📃: scim.ag/46zAaLi

Enjoying a great #HIVR4P2024 meeting by @iasociety with @NachoRelano and @rumihabib from @TheWistar in Lima this week😍. Thank you to the @gatesfoundation for hosting a fun reception this evening. #HIVvaccines 💪

HIV-1 neutralizing antibodies in SHIV-infected macaques recapitulate structurally divergent modes of human V2 apex recognition with a single D gene biorxiv.org/cgi/content/sh… #bioRxiv

Authored by Andrew G. Soerens et al, we show that #Tcells are capable of proliferating in response to iterative stimulation for over 10yrs! And produce enough progeny to occupy a volume 30,000x the Earth's volume! @Nature nature.com/articles/s4158…

We developed a new multivalent mRNA vaccine against all known influenza virus subtypes. Our study describing the vaccine was just published in @ScienceMagazine. 1/n science.org/doi/10.1126/sc…

Great and productive #CAVDannualMeeting by @gatesfoundation in Seattle last week. We presented our work generating #NewMouseModels for #HIV #Vaccine development by Belen Palacio @mb_palacio, Ignacio R. Relaño @NachoRelano and Ashwin Skelly at @TheWistar

A germline-targeting chimpanzee SIV envelope glycoprotein elicits a new class of V2-apex directed cross-neutralizing antibodies biorxiv.org/cgi/content/sh… #biorxiv_immuno

Why are Pakistan’s floods so extreme this year? #Echobox=1662285436" target="_blank" rel="nofollow noopener">nature.com/articles/d4158…

Strategies for HIV-1 vaccines that induce broadly neutralizing antibodies dlvr.it/SWWDgX

Virus-like transposons cross the species barrier and drive the evolution of genetic incompatibilities biorxiv.org/cgi/content/sh… #bioRxiv

Incredible paper out in @Nature nature.com/articles/s4158…

Our latest HIV vaccine paper is out! We demonstrate that an Env-encoded nucleic acid vaccine retains a native-like trimer antigenic profile in vivo and results in unique neutralization which we mapped by cryo-EM. nature.com/articles/s4146…

Our SARS-CoV-2 nanovaccine paper is out! We describe the development of immune-focused receptor-binding domain nanoparticle vaccines which elicit potent and durable neutralizing antibodies against SARS-CoV-2 and variants of concern. @CellReports sciencedirect.com/science/articl…

Phenomenal paper just published in Science persuasively demonstrating that EBV causes most if not all multiple sclerosis. Phenomenal epidemiological design and technical achievement. 👏 science.org/doi/10.1126/sc…

"In Pakistan, more than 40 million children were unable to receive measles vaccination and around 50 million children missed polio vaccination in 2020. Moreover, more than 36 million children did not receive vitamin A supplementation in 2020."

One of the most startling Covid charts I’ve made in a long time, on vaccine inequality: Rich countries have given out more booster shots in the last 3 months, than poor countries have given out total doses all year. @donatopmancini’s story: ft.com/content/35a3d4…

Virus vaccines: proteins prefer prolines. Sanders & Moore review a method devised for #HIV #vaccine development that was utilized in most #COVID19 vaccines-- stabilization of the spike protein by appropriately positioned proline amino acid substitutions cell.com/cell-host-micr…