Latin American School of Oncology (ELO)

Dra. Claudia Sheinbaum Pardo: Designar al Instituto Nacional de Cancerología con el nombre de "Dr. Jaime G de la Garza Salazar - ¡Firma la petición! chng.it/PrMZ6YBkM4

The Devil Lies in the Details: An Analysis of Six Oncology Randomised Controlled Trials - Article (Preprint v1) by Alfonso Dueñas-Gonzalez et al. | Qeios qeios.com/read/RNYMQG

qeios.com/read/RNYMQG THE DEVIL LIES IN THE DETAILS: AN ANALYSIS OF SIX ONCOLOGY RANDOMISED CONTROLLED TRIALS Abstract Randomized Controlled Trials (RCTs) in oncology are the backbone of advancing the clinical practice of oncology. Their significance is particularly pronounced in high-impact and influential journals such as the NEJM, The Lancet, The Lancet Oncol, JAMA, JAMA Oncol, and JCO. However, previous works have highlighted that RCTs often fail to provide complete reporting of survival endpoints, which can jeopardize the oncologist's interpretation of the study findings.This is a narrative review in which we provide some basic concepts of survival statistics and apply these in the analysis of six RCTs published in these six journals. These articles were selected solely by scanning the latest issues (printed) on the journals' web pages. The first RCT on a solid tumor to appear in the corresponding journals was selected. No other criteria were applied.We found that these six trials failed to provide crucial data, such as the number of survival events, patient censoring, and the presentation of both absolute and relative effect sizes on survival, to different extents.This report study focuses solely on a small subset of RCTs from high-impact journals, which may not represent the reporting practices of oncology RCTs published in other journals or at different times. The most well-informed party should be the patients, who ultimately benefit from improved RCT reporting. We hope this work will inspire oncologists to sharpen their skills in analyzing RCTs and encourage statistician experts to contribute their valuable insights and knowledge on this issue.

“The commentary highlights the importance of comprehensive statistical reporting in high-impact journals to inform clinical practice effectively.” youtu.be/kja2b0fmj7Y

Sotorasib's Impact on KRASG12C-Mutated NSCLC by Dueñas-Gonzalez & Gutier... youtu.be/kja2b0fmj7Y?si… vía @YouTube

Sotorasib Treatment Could Worsen the Prognosis of Advanced KRASG12C-Mutated Non-Small Cell Lung Cancer - Article (Preprint v1) by Alfonso Dueñas-Gonzalez et al. | Qeios qeios.com/read/A8NMJD

pubmed.ncbi.nlm.nih.gov/39159409/ Community Led Actions in Oncology. Read the Innovations by LA radiooncologsits to cope with COVID-19. Your comments will be welcome. 🧐☢️

PUBLISHED: Our NIH-funded CLARO PARTE study for Latin America and the Caribbean Countries suggests scalable practices in #radiationoncology clinics to guide actions during future large-scale public health crises in low- and middle-income countries 👉🏼 ascopubs.org/doi/10.1200/GO…

Latin American Cancer Week, #Selac May 13-17, 2024, will provide a 360° picture of the impact of the growing global incidence of #cancer, the challenges it presents for the implementation of strategies for its control. @OrgSlacom selac.org

“ Choosing Wisely in oncology in Latin America: what SLACOM does not recommend in the care of cancer patients in Latin America”, Table 5. Top ten 'CW recommendations in oncology in Latin America. doi.org/10.3332/ecance…

We're delighted to announce the launch of "#ChoosingWisely in Oncology in Latin America" 🚀 At @ecancer , we're committed to driving positive change in healthcare, and this is another step towards realizing this vision. #EducationsSavesLives ecancer.org/en/journal/art…

Honor a quien honor merece.

Para preparar un litro de refresco se utilizan más de 200 litros de agua. Dejar de consumir refrescos es cuidar el agua. #Agua #Refresco

ELO TALKS. LATIN AMERICA AND THE CARIBBEAN CODE AGAINST CANCER An Interview with EDUARDO CAZAP, MD,PhD, FASCO Emeritus Professor Latin American School of Oncology (ELO). youtube.com/live/ylM__HETj…

Latin America and the Caribbean Code against Cancer. Eduardo Cazap, MD,... youtube.com/live/ylM__HETj… vía @YouTube

ELO TALKS. Wednesday 7th,2024. Live from Buenos Aires 19:00 ; Mexico City 16:00.