Marc Demillequand, PhD, Chem Lc.🇧🇪

Your mitochondria aren't just "powerhouses," they're master regulators. TCA cycle intermediates aren't just fuel. They're signaling molecules that directly influence stem cell function, immune responses, tumor development, and even lymphatic vessel formation. → Acetyl-CoA exits the mitochondria to drive histone acetylation and lymphangiogenesis → α-ketoglutarate and its derivative L-2-HG toggle between stem cell maintenance and immune modulation → Itaconate (derived from aconitate) has emerged as a key immunometabolite → Succinate and fumarate accumulation can drive tumorigenesis through epigenetic dysregulation practically speaking, supporting mitochondrial health isn't just about energy. Strategies like calorie restriction, aerobic exercise, and targeted nutrients (B vitamins, magnesium, CoQ10, alpha-lipoic acid) help maintain TCA cycle flux, which means better cellular signaling, not just better ATP production. if someone asks you why mitochondrial support matters beyond "feeling more energetic," this is why. Figure from Martínez-Reyes & Chandel, Nature Communications (2020)

🚨JD VANCE: "The sickest that I have been in the last 15 years, BY FAR, was when I took the vaccine." "My heart was RACING.... the fact that we're not even allowed to talk about that.." "A lot of people I know, they talk about the second dose made them really, really SICK."

As I always predicted: the mass gain-of-function experiment- aka large-scale C-19 vaccination- would transform SC-2 into a completely different CoV with unprecedented features. Cicada is definitely not the end; it’s only when ´smart’ glycan-mediated mutations get selected that all remaining adaptive immune hurdles in the host will be overcome. The host will then need to rely on innate, cell-mediated immunity to kill virus-infected cells at an early stage of infection. That type of immunity got well trained in the unvaccinated -no worries, children right now more sensitive to BA.3.2 will catch up! -whereas that’s not the case in those who prevented their innate cell-based immunity from confronting the virus by virtue of high anti-S Abs (i.e., the vast majority of C-19 vaccinees). This comes on top of the chronic illness several C-19 vaccinees are now exposed to, which our health authorities and the vaccine industry don’t give a damn about. HiViCron is looming behind the door of highly C-19-vaccinated populations.

La colère froide d'Agnès Buzyn, accusée de vénalité (sans l'ombre d'un élément tangible) par la députée LFI Ersilia Soudais, en audition de commission d'enquête sur l'audiovisuel public et la science, hier. Ersilia Soudais rappelée à l'ordre par le président.

Trump thinks Zelensky is nothing more than a great salesman. In fact, Zelensky is far beyond Trump's ability to grasp. Trump simply has no understanding of honor, or decency, or morality, or courage, or patriotism, or intelligence. And he hates anyone who does understand.

The German chemical giant BASF had had enough of anti-Russian sanctions and European regulations and built a plant the size of half a city in China, where it can source Russian gas.

❌️🇪🇺 Carcassonne : le nouveau maire RN retire le drapeau européen du fronton de la mairie.