Sean Dempsey

@DrKevinMorgan @QUBCCE Thanks Kevin!

@CatalysisSciTec Thank you, it was great getting to take part in this years #RSCPoster

Congratulations to #RSCCat runner up @sdempsey04 for the great #RSCPoster on continuous #flowchem for BN hydrogenation!

@deuxbeck @mikhaileydiane Thanks Damien!

Winners of #RSCPoster are announced! Congratulations to @mikhaileydiane and @sdempsey04 who won in the #RSCCat category!

@LianeGroup @qubappflow @QUBCCE @AlmacGroup Hi Liane, thanks for your question! Yes, the presence of Et3N makes purification of product more difficult. It's hoped that most of the Et3N could be removed from benzylamine product through aqueous extraction and careful selection of pH(as both amines have different pKaH values)

@sdempsey04 @qubappflow @QUBCCE @AlmacGroup Any concern about product purification when using formate (Et3N) instead of formic acid?

Happy to share my #RSCPoster with you all! Continuous-flow transfer hydrogenation of benzonitrile using formates as a safe & sustainable source of hydrogen. #RSCCat #RSCEnv @qubappflow @QUBCCE @AlmacGroup

@deuxbeck Another 'way around' the issue would be to have two catalyst beds. While one is running the reaction, the other is being regenerated (by washing with water). In this way, there would be constant stream of product. We are hoping to demonstrate this in the future.

@deuxbeck Hi Damien, thanks for your question! Yes, as formate is the H-source for this reaction it's difficult to avoid eventual deactivation, even after optimisation of key reaction parameters. We are currently looking into ways around this, including the use of other H-transfer agents

@flowithefish @qubappflow @QUBCCE @AlmacGroup In industry, it would be possible to have two catalyst beds. While one is running the reaction, the other is being regenerated (by washing with water). In this way, there would be constant stream of product. We are hoping to demonstrate this in the future.

@flowithefish @qubappflow @QUBCCE @AlmacGroup Hi Laura, thanks for your question! We extended the catalyst lifetime to 7 hours on stream before seeing deactivation (at flow rate of 0.5 ml/min). This is compared to deactivation within one hour before optimisation.