Sebastian Burgstaller

I m happy to present our latest preprint, and the main work of my PhD-project: "GTestimate: Improving relative gene expression estimation in scRNA-seq using the Good-Turing estimator" In this manuscript we introduce a new normalization method for scRNA-seq data.

🤯 The level of sophistication of the XZ attack is very impressive! I tried to make sense of the analysis in a single page (which was quite complicated)! I hope it helps to make sense of the information out there. Please treat the information "as is" while the analysis progresses! 🧐 #infosec #xz

@andrewsu I intended to convey that I found the atmosphere at the meeting depressing, from the very beginning. Hope that helps, Andrew!

@andrewsu Q: But you were still using the sentence that you felt treated very unfairly (discriminated against?). A: Using the term "very unfairy treatment/discriminated against" was a mistake. Unfortunately, I did it because I had the article of CNV infront of me.

Would a native German speaker be so kind as to translate this passage for me? In particular, I'm getting conflicting translations of "bedrückend" as either "depressing" or "oppressive"...

Building a Rust-y Vim clutch with the Raspberry Pi 2040 by Chris Price: blog.scottlogic.com/2022/12/08/bui… #embedded

Today, we’re introducing a new model that eliminates accept/reject decisions. By publishing every paper with eLife reviews as a Reviewed Preprint, we plan to restore autonomy to authors, ensuring that they will be judged by what, not where, they publish. elifesciences.org/inside-elife/5…

New open-source language model from Google AI: Flan-T5 🍮 Flan-T5 is instruction-finetuned on 1,800+ language tasks, leading to dramatically improved prompting and multi-step reasoning abilities. Public models: bit.ly/3sbNPDJ Paper: arxiv.org/abs/2210.11416

My matrix visualizations with MIT Gilbert Strang. I compiled the graphics in a short(14-page) PDF paper! github.com/kenjihiranabe/…

1/ You’ve sequenced your samples and identified variants. Great! 🙌 Now, here's how you can use @ensembl to find out the effect of your variants on #protein structures and interactions. A thread...🧵 #genomics #bioinformatics #tweetorial #Ensembltraining 🧬

Happy to share our preprint showing improvement of variant calling and expression analysis by fixing errors in GRCh38 reference. With @sedlazeck, Justin Zook @NIST @meganamsu Jonathan LeFaive, Peter Orchard @MedhatHelmy7 @lfpaulin @dcsoto_cl @BCM_HGSC biorxiv.org/content/10.110…

Two years in the making, my take at illustrating bird phylogeny: deviantart.com/albertonykus/a…

I have waited this, for 20 years 🤣. Still, thanks to @nvidia for finally getting this done!

We reveal your models of sequence #evolution. Our latest contribution to #phylogenetics using #DeepLearning: "ModelRevelator: Fast phylogenetic model estimation via deep learning" biorxiv.org/content/10.110… #NeuralNetworks #phylogenomics

Hot off the press: Can we use weak supervision to extract large-scale datasets from social media? Turns out we can do this for tweets with drug mentions! great work by @ramyatekumalla published on the @_LXAI research special issue link.springer.com/article/10.100…

@drjmbanda , fav cu

And there is even a competitor #neuralnetwork for #proteinfolding, published in @ScienceMagazine science.sciencemag.org/content/early/…

Finally, the alphafold2 paper has been released: nature.com/articles/s4158… #deeplearning #MachineLearning #proteinfolding #AI

From our campus: Multiplexed detection of SARS-CoV-2 and other respiratory infections in high throughput by SARSeq. #SARSCoV2 #COVID19 nature.com/articles/s4146…

Twenty years since the official first draft of the human genome, a groundbreaking effort on many levels. #humangenome #genomics #bioinformatics nature.com/articles/d4158…

Die absoluten Zahlen steigen bisher nicht in Österreich. Jedoch verdrängen die Varianten kontinuierlich die herkömmlichen Viren. Das läßt vermuten, daß der bisherige Lockdown zwar funktioniert, aber nicht effektiv genug für Varianten mit erhöhter Infektiösität ist. 6/7