Mike Shepanski 🇺🇸 retweetledi
Trump's gotta start focusing on home.
Market is fucked.
Gas prices are fucked.
Price of everything is fucked.
People are struggling out there.
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Mike Shepanski 🇺🇸
48.8K posts
Mike Shepanski 🇺🇸
@shepski79
Married to MY Beautiful Wife, Father of 3 MEN. #BillsMafia. UPS Driver, Teamster. Weather geek. Living in The People’s Republic of NYS.
Chili Center, NY Katılım Kasım 2011
1.4K Takip Edilen4.6K Takipçiler
Is anyone else concerned of what the price of gasoline will be around Memorial Day Weekend is this shit keeps up?
PM Breaking News@PMBreakingNews
Breaking: Smoke rising from Haifa’s oil refinery in Israel. The refinery is one of the most strategically important industrial sites in Israel.
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@ArlineL0 Across from Lowe’s and Canandaigua road by the canal.
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Mike Shepanski 🇺🇸 retweetledi
Dear rich people in Florida,
Please come back to New York so the Democratic Party can f--k you some more.
Signed,
Comrade Kate
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Mike Shepanski 🇺🇸 retweetledi
Shorter Kathy Hochul: Please come back to this abusive relationship so we can keep beating you
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Mike Shepanski 🇺🇸 retweetledi
It is time for a reality check‼️
Those who argue that the NYS will impact climate change are ignoring basic global emissions data.
China’s emissions alone increased by 570 million tons between 2022 & 2023. This is merely their year-over-year increase.
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@RochesterSpirit Yes. They hide it well! Had a customer who lived on a golf course and her garage was full of unopened QVC boxes.
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@shepski79 I went into so many of these homes when I was a cop. It is far more common than people would think.
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It’s a mental illness, and we lost one last month in Fairport….nicest lady in the world, but had a severe hoarding problem that likely caused her death in a house fire off Whitney road.
𝕰𝖒𝕲@Emilio2763
What Tf?!… All Full Amazon Boxes Keep getting Ordered…
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Mike Shepanski 🇺🇸 retweetledi
American Hero Bryce Harper salutes and points to the flag on his sleeve as he rounds the bases
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Mike Shepanski 🇺🇸 retweetledi
Scientists found an off-switch for high cholesterol – and it could save millions of lives.
In a major breakthrough, researchers at the University of Texas at Arlington have uncovered what could be the body’s “off switch” for managing cholesterol during inflammation—potentially opening the door to new treatments for heart disease, diabetes, and even cancer.
The key lies in an enzyme called IDO1, which activates during inflammation. Under normal conditions, immune cells called macrophages help absorb cholesterol. But when inflammation kicks in – from stress, infection, or injury – IDO1 throws a wrench in the system. It triggers the production of a chemical called kynurenine, which stops macrophages from doing their job. Cholesterol builds up. Arteries clog. Disease follows.
When scientists blocked IDO1 in lab settings, those cells regained their cholesterol-regulating ability—suggesting it may be possible to halt disease progression before it begins.
The study didn’t stop there. Scientists also identified another enzyme, nitric oxide synthase (NOS), which worsens IDO1’s effects. Targeting both IDO1 and NOS together could lead to powerful new therapies aimed at preventing inflammation-related illnesses at their source. With cardiovascular disease and diabetes among the world’s leading killers, this discovery could mark a turning point in how we treat—and even prevent—some of the deadliest modern conditions.
[“Can Enzyme Behind High Cholesterol Be Turned Off?” University of Texas at Arlington News, 2025]
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@DBIMGMTGROUPLLC Minimum wage and nasty, entitled employees didn’t help!
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This is crazy.. and ppl wonder why a lot of fastfood places are going out of business and even family style restaurants.
NewsForce@Newsforce
POPEYES FRANCHISE GOES BROKE ON $233M IN CHICKEN One of the largest Popeyes franchise operators in the U.S. just filed for Chapter 11 after losing $18.8 million despite generating about $233 million in sales. The company, Sailormen Inc., has already closed more than 20 locations while thousands of employees wait to see which stores survive the bankruptcy process. Apparently selling mountains of fried chicken still isn’t enough when rent, labor, and food costs all decide to show up angry at the same time. Source: NewsForce
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We just need more trampoline parks!
Officer Lew@officer_Lew
WATCH🚨: Before the shots rang out at Daytona Beach, FL...This is what Spring Break looks like in 2026 😳🏖️🔫
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@RHill4241 @barstoolsports These guys practice these shots all the time AFTER practice, and sometimes they work out.
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@barstoolsports Wow, did you see this?@shepski79
That is one bad ass goal
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A goal so crazy you have to see it to believe it
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It’s official 315!
Your MAN is back starting tomorrow morning in Macedon….might be dipping a toe in Palmyra at times.
Fairport/Perinton😘
GIF
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@Marcus4Roc You hear gunshots, but we all hear/feel the wind.
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So I'm just trying to sleep and it's 12: 30 a.m. and they're shooting down the street SMH here come the sirens 🚨🚓
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