Shiv Rao, MD
2.1K posts

Shiv Rao, MD
@ShivdevRao
Building @AbridgeHQ + random musings at intersection of Warp records, late 90s skateboarding, Vincent Van Duysen, and cardiology.



I think David George is one of the great growth investors today. But I also think some of the hardest and most pressing questions have not been asked. - How does a $5BN fund do a 5x? - Why invest $300M into Adam Neumann? - You say, “diamonds in the rough”, and largest positions are SpaceX, Stripe and Anduril… what am I missing? This is one of the spiciest shows we have ever done. Spotify 👉 open.spotify.com/episode/78O9tV… Youtube 👉 youtu.be/IxoGRY6TXwk Apple Podcasts 👉 podcasts.apple.com/us/podcast/20v… My biggest takeaway from @DavidGeorge83 👇 Timestamps: 00:00 Intro 01:24 Why Everyone is Wrong: Mega Funds Does Not Reduce Returns 07:13 The Biggest Advantage of Staying Private for Longer 11:02 Is Public Market Capital Actually Cheaper Than Private Capital? 22:42 The #1 Investing Rule for a16z: Always Invest in the Founder's Strength of Strengths 30:23 Does Revenue Matter as Much in a World of AI? 30:54 Does Kingmaking Still Exist in Venture Capital Today? 43:48 Do Margins Matter Less Than Ever in an AI-First World? 47:01 My Biggest Miss: Anthropic and What I Learn From it? 48:15 Has OpenAI Won Consumer AI? Will Anthropic Win Enterprise? 52:50 The Most Controversial Decision in Andreessen Horowitz History 55:59 Why Did You Invest $300M into Adam Neumann and Flow? 59:17 Quick-Fire Round





We’re excited to share that @jacobeffron has been promoted to Managing Director at Redpoint. Since joining the firm in 2020, Jacob has built a reputation as one of the most thoughtful and trusted voices in venture. His investments in companies such as @AbridgeHQ , @WeAreLegora, @getgarner, @ScribeHow, @AcuityMD, @tryramp, @physical_int, @poolsideai, @Deliverect_com, @StriveHealthUS and @ideogram_ai speak volumes about his ability to identify and support transformational teams. Great founders consistently seek Jacob out. He is known for his intellectual rigor, first-principles thinking, and relentless commitment to helping entrepreneurs succeed. He is not only a valued thought partner but someone whose insights and contributions materially shape the companies he works with. Internally, Jacob brings the same clarity and commitment that define his work with founders. He sharpens every discussion, builds conviction through outstanding diligence, carries himself without ego, and consistently leads by example. That combination of humility and intellectual drive is rare. Most importantly, he is a genuinely good person and a pleasure to work with. Jacob’s drive to create lasting, high-quality work can also be seen in his two podcasts—Vital Signs and Unsupervised Learning—focused on healthcare and AI, respectively. Both are trusted resources for founders, operators, and investors looking to understand and navigate the most important innovations of our time. In this business, few signals are clearer than the respect of great founders and the conviction of your partners. Jacob has earned both. We’re fortunate to call him a colleague, and even more excited for what lies ahead as we continue building with him. Congratulations, Jacob! - Scott, Elliot, Logan, Annie, Erica, Satish, and Alex







New @NoPriorsPod 🔥 Conversations Are The Source of Truth in Healthcare, w/@ShivdevRao founder @AbridgeHQ - the potential of AI in healthcare - why documentation is the right first problem - solving burnout, a crisis for clinicians - building domain-specific AI tools







