Simon Snoeck retweetledi
Disulfide bond sculpts a peptide fold that mediates phytocytokine recognition biorxiv.org/content/10.110… #biorxiv_plants
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Simon Snoeck
30 posts
Simon Snoeck
@snoeck_simon
Postdoctoral researcher, Cyril Zipfel's group (IPMB, University of Zurich), Latest story: https://t.co/0NtSqWVFgB
Katılım Mayıs 2021
172 Takip Edilen141 Takipçiler
Shedding light on the structure-function mechanisms of LRR-RPs. Our research merges #AlphaFold3, years of literature and functional validation to reveal diverse ligand-binding mechanisms and a conserved co-receptor association mechanism. biorxiv.org/content/10.110…
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Simon Snoeck retweetledi
We proudly present: Tomatoes have MIK2, too: However, it does not sense SCOOP peptides but a Fusarium elicitor. Thanks to all collaborators for the support.
biorxiv.org/content/10.110…
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Simon Snoeck retweetledi
Are you interested in receptor kinase signalling and plant immunity? We have several positions open to join our team at
@TheSainsburyLab in Norwich.
#plantscience
#mpmi
#plantimmunity
#sciencejobs
Please get in touch if you have questions
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Simon Snoeck retweetledi
Plant pattern recognition receptors: from evolutionary insight to engineering go.nature.com/3Z5pBwp #Review by @snoeck_simon, Oliver Johanndrees, @ThorstenNrnber1 & Cyril Zipfel
Free to read here: rdcu.be/dZPdL
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Simon Snoeck retweetledi
In @NatureRevGenet: "Plant pattern recognition receptors: from evolutionary insight to engineering" rdcu.be/dZPdL
...summarizes both established and innovative approaches to () translate resulting evolutionary insights into engineering PRR recognition specificities.
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Intriguing role for N-glycosylation in LRR-RK activation: doi.org/10.1038/s41477… and doi.org/10.1038/s41477….
Glad to see that cryo-EM and crystallography pinpoint the same ligand binding pockets as AF:
doi.org/10.1073/pnas.2…
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Simon Snoeck retweetledi
Reverse engineering of the pattern recognition receptor FLS2 reveals key design principles of broader recognition spectra against ... biorxiv.org/cgi/content/sh… #biorxiv_plants
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Leveraging CZL, coevolutionary insights and AI-based structural modeling to unravel receptor–peptide ligand-binding mechanisms | PNAS pnas.org/doi/10.1073/pn…
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Simon Snoeck retweetledi
Ten days left to apply! We will try to make a new generation of selective pesticides based on the natural defense system in plants. #ERC_research #plantscijobs #postdoc #academicjobs. Thx for RT last time, feel free to RT again or notify people that might be interested! 🙏
Simon Stael@SimonStael
All I want for Christmas is a new Postdoc🎶🎄. Come join this fantastic team in Uppsala to work on protein engineering and plant-insect interaction! Please RT! #ERC_research @PlantSlu #plantscijobs More info and application via the link slu.se/en/about-slu/w…
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"Leveraging co-evolutionary insights and AI-based structural modeling to unravel receptor-peptide ligand-binding mechanisms". We identified 2 MIK2 binding pockets which interact with the conserved SxS SCOOP motif in a relatively quick and inexpensive way. biorxiv.org/content/10.110…
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Simon Snoeck retweetledi
One week left to apply for this postdoc position!
Nick Wybouw@NWybouw
We are hiring a post-doctoral researcher! The 2-y research position focuses on dissecting the molecular mechanisms that cause hybrid defects. We focus on both symbiont- and nuclear-mediated hybrid dysfunction. Apply before April 3. For more info, visit nickywybouw.org/images/PD-ONLI…
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It felt like a good time to write down some accumulated insights on RLPs. Basically, the guide I wish I had when I started studying them 3years ago.
Adam Steinbrenner@ADSteinbrenner
New review preprint w @snoeck_simon @anthonygkgarcia Plant Receptor-like proteins (RLPs): Structural features enabling versatile immune recognition We analyze RLPs in light of the exciting new RXEG1 structure. Your feedback would be really appreciated! zenodo.org/record/7587551
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I joined the recently established lab of @ADSteinbrenner 3 years ago, to this day exactly. I guess this is a proper way to celebrate our anniversary? ;) Thanks for the opportunity Adam, I had a blast with this one!!
Adam Steinbrenner@ADSteinbrenner
Our paper with work by @snoeck_simon and @anthonygkgarcia is out today in @eLife ! We describe the evolution of herbivore peptide recognition by a plant immune receptor, and resurrect the sequence of the ancestral gene from ~28 million years ago. elifesciences.org/articles/81050
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@snoeck_simon Good to hear you made it back 'home' safe and was great meeting and having you in Uppsala!
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Last time flying back "home" to Seattle. Glad I got the opportunity to visit both SLU and UZH. Excited to start a new chapter in 2023. Also, both places have affordable and great bakeries :)
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@JWR_nhf Thanks Jack, just made it back. It was a pleasure to meet you, and that counts for all 3 cities ;)
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One to remember, so glad I got the opportunity to join and share my work after three years of talking to my computer.
Melinka Butenko@MelinkaAlonso
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