StatsCI

It provides evidence that there is still a lack of uptake of the estimand framework in RCTs & how clear guidance on how to implement the estimand framework to trials with an adaptive design is needed

In 2024 we hosted Hannah Wallace and Fran Piazza as part of the NIHR Undergraduate Internship Programme and NIHR RSS Imperial College London & Partners Hub - this review summarises the findings from their research project!

📣New Publication: Investigating estimand considerations in adaptive trials: a systematic review link.springer.com/article/10.118…

📚 All I want for Christmas…is a precisely defined research question link.springer.com/article/10.118…

Last week we enjoyed Victoria Cornelius's Inaugural lecture! Under pressure: smarter trials for better health outcomes - covering traditional trials to Bayesian, adaptive, and decentralised approaches. If you missed it - you can watch the recording here: youtube.com/watch?v=DpejpM…

📢 New publication in #Trials led by @Suzie_cro with the HEALTHY STATS public involvement group: Supporting public involvement in defining estimands: a practical tool accessibly explaining the five key attributes of an estimand trialsjournal.biomedcentral.com/articles/10.11…

📢 New blog post: statsci.co.uk/post/highlight… One of our NIHR pre-doctoral fellows Xiao Xuan Tan recently attended ISCB 2025 which was packed with cutting-edge statistical research & inspiring keynotes. Read all about her key highlights & takeaways from attending the conference

Our Research Methods Academy Seminar Series: 2nd trials seminar  Prof. Karla Hemming will be discussing the updated guidelines for Statistical Analysis Plans in Cluster Randomised Trials, ensuring transparency & credibility in trial design Register: imperial-ac-uk.zoom.us/webinar/regist…

New publication 📢: A Bayesian framework to evaluate non-inferiority in randomised controlled trials of uncommon conditions - Journal of Clinical Epidemiology led by Victoria Cornelius jclinepi.com/article/S0895-…

📢 Chelsea&Westminster NHS Trust Research Dept. are looking for an enthusiastic & dedicated senior statistician with experience working on drug trials to lead on the statistical work for a small portfolio of sponsored studies. For details please see here: chelwest.nhs.uk/about-us/work-…

💬Got 5 mins? Help improve clinical trials by sharing your thoughts on health data collection. Annie Wright a PhD researcher at Imperial has designed this survey with the help of her public involvement groups. imperial.eu.qualtrics.com/jfe/form/SV_... #PPI #HealthEquity #ResearchVoices

New publication 📣: Are estimands being correctly used? A review of UK research protocols by Timothy P. Clark, Richard H. Wicentowski, Suzie Cro, Matthew R. Sydes & Brennan C. Kahan trialsjournal.biomedcentral.com/articles/10.11…

🎉 Excited to welcome two NIHR Pre-Doc Fellows! Hannah Wallace from Scotland who will work with @RachPips & @Suzie_cro. And, Oluwaseun Olayiwola from Nigeria who will work with @LeilaJTF , @Suzie_cro and @DrKGibbons .

Attending the International Society for Clinical Biostatistics this week? @ISCB_info Don’t miss @ellievanvogt and Xiao Xuan who will be presenting these exciting topics:

Meet Alex Dixon, who is spending his summer experiencing life within ICTUs statistics and trial methodology group and conducting a research project with us as part of an NIHR undergraduate internship Find out what he has been up to here: statsci.co.uk/news

🔊We're hiring! Imperial Clinical Trials Unit are looking for an ambitious senior statistician with experience in clinical trials including adaptive trials, to lead a research programme in antimicrobial resistance & data-enabled trials. Full details: imperial.ac.uk/jobs/search-jo…

Delighted to share registration is open for Professor Victoria Cornelius's inaugural lecture -Under pressure: smarter trials for better health outcomes- Thursday, 30 October 2025, 17.30-18.30, Imperial College South Kensington. For details & registration: imperial.ac.uk/events/196880/…

New publication📣- Incorporation of Patient & Public Involvement in Statistical Methodology Research: Summary of Workshop Proceedings -aimed at addressing barriers to meaningful PPI in statistical methodology research. Open access in Statistics in Medicine onlinelibrary.wiley.com/doi/10.1002/si…

Attending NIHR stats conference this week @NIHRStatistics ? Don’t miss @Annie_Stats , @LeilaJTF , @JakElkes , @marie_miller_ , and Francesco Lala, who will be presenting these exciting topics:

You can catch up on all of the Trials Special Series on #AdverseEvent webinars curated by @RachPips and @VR_Cornelius so far on: statsci.co.uk/webinar-series