Synple Chem

After a great opening ceremony, fantastic lecture by Jeffrey Bode, and busy first exhibition session, we're ready to do it all again today at the IX EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry! ow.ly/IfRB50PHhrn ow.ly/KrNP50PHhrW

Still a good one ... ow.ly/ZToO50PEQEi #chemistryjokes #sciencehumour #humor

Some companies recognise the need to adopt new technologies, but it will only happen if there's a willingness to try “something new”. Some technologies might be all hype, but if we don’t try, we’ll never know... ow.ly/Xl1550PgjMY ow.ly/Jswe50PgjPA #drugdiscovery

An insightful overview of the emerging field of skeletal editing... ow.ly/3gRv50OR0uk ow.ly/t83S50OR0uj #drugdiscovery

This review provides a useful overview of C-H bond activation in highly functionalized molecules. ow.ly/kYck50OLAfU ow.ly/Cnfq50OLAfT #C-Hactivation #catalysis

This paper reports on the use of sulfenate anion organocatalysts for the preparation of trans-aziridines. ow.ly/uzcL50OnQJc ow.ly/7C7t50OnQTn #organocatalysis #synthesis #aziridines

Delighted to share our new paper from Digital Discovery on the easy, robust automation of PROTAC synthesis. Check it out if you want to know more about synplifying your PROTAC preparation! #protacs #digitaldiscovery #medchem ow.ly/hB9x50OsBvP ow.ly/vnOV50OsBwU

This paper reports on various new deconstructive functionalisations of cyclic aliphatic amines to achieve skeletal diversification. ow.ly/5M5x50OnPGf ow.ly/ho2750OnPGh #synthesis #amines

Interested in having a look behind the scenes at Synple Chem? Then check out this new video by Sebastiano Rupiani! ow.ly/MThx50OnOrR ow.ly/KQvf50OnOrQ #synplechem #merck #synthesis #capsulechemistry #labautomation

Check out this article, which looks at the impact that the Ro5 has had on medicinal chemistry over the last 25 years and the relevance of this rule today and in the future. ow.ly/B8ln50OnNZc ow.ly/sn8f50OnNZe #Ro5 #medchem

Want to know more about optimising chemical reactions? Check out this new review and find out about all the techniques available. ow.ly/kiM850OnNkK ow.ly/S0BE50OnNkI #reactions #optimisation #synthesis

Delighted to share this new Org. Lett. paper from our work with @bode_lab on the development of a Synple automated process for Suzuki−Miyaura cross couplings! ow.ly/HTgf50O6lAb ow.ly/OoRg50O6m3q #suzuki #synple #labautomation

Hot on the heels of PROTACs, what's next in the field of proximity-inducing drugs? Check out this review for more information! ow.ly/rxX150Nsjft ow.ly/2fSe50Nsjfu #drugdiscovery #medicinalchemistry

An insight into why Bill Gates thinks AI will be truly revolutionary... ow.ly/tmMY50NsiZF ow.ly/9iNU50NsiZE #ai #BillGates #technology

Check out this review highlighting some of important developments in chemical biology. ow.ly/Cr5150NsiVK ow.ly/NLvX50NsiW5 #medicinalchemstry #chemicalbiology #drugdiscovery

DO MORE, FASTER - equip yourself with Synple enabling tools and give your synthesis efforts a boost! ow.ly/BWpn50NsiP5 #synple #synthesis #enablingtools #productivity

Check out this perspective on the use of FBDD for the discovery of new E3 ligase ligands... ow.ly/Sy9O50Nlcyw ow.ly/lJL350Nlcyv

Rewarding our brilliant team with a pizza lunch for all their amazing efforts getting more big orders prepped and shipped to customers! ow.ly/Jm1e50Nl3Zt #synplechem #teamwork #thankyou #rewards #madeinswitzerland #swissmade

Methodologies that accelerate hit discovery are desirable and multicomponent reactions that give rise to some complex, interesting looking scaffolds present a great option for this. ow.ly/iMqL50Njbc2 ow.ly/qtwP50Njbc1 #medchem #synthesis #drugdiscovery

Check out this transition-metal-free borylation of benzylic alcohols! ow.ly/GXzn50Nfs88 ow.ly/AHxe50Nfs87