Target 2035

492 posts

Target 2035

@target2035

🌍 open science movement to develop by 2035 pharmacological tools for all human proteins; https://t.co/7QqI6Xb48s & https://t.co/SR2W97oLbs

Worldwide Katılım Ağustos 2021

390 Takip Edilen551 Takipçiler

Target 2035 retweetledi

Albert A. Antolin (he/him)@antolin_aa·16 Ara

#MAINFRAME is launching! This international, #OpenScience Network brings #MachineLearning & #compchem scientists together to create open-source algorithms & benchmarks for tackling real-world challenges in #DrugDiscovery. Join us: aircheck.ai/mainframe

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Target 2035@target2035·13 Ara

#MAINFRAME is an #OpenScience Network, supported by Target2035 & ultra-large-scale experimental screening data, brings #MachineLearning & #compchem scientists together to create open-source algorithms & benchmarks tackling #DrugDiscovery challenges. aircheck.ai/mainframe

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Target 2035 retweetledi

Structural Genomics Consortium (SGC)@thesgconline·4 Ara

New episode for our Target 2035 Podcast Series 🎧 @MilkaKostic talks with @aledmedwards to unpack his journey from a traditional research scientist to a passionate open science advocate. Listen here: bit.ly/3AZQkBm

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Target 2035 retweetledi

Structural Genomics Consortium (SGC)@thesgconline·25 Kas

A fully open framework for DEL-ML hit discovery. We replace explicit DEL compound structures with ML-ready chemical fingerprints, enabling the broad scientific community to advance DEL-ML models and refine discovery methods. All data available on AIRCHECK. chemrxiv.org/engage/chemrxi…

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Target 2035 retweetledi

Structural Genomics Consortium (SGC)@thesgconline·21 Kas

A well anticipated overview highlighting the first CACHE challenge, which brought together 23 research teams from 10 countries to collectively predict 1,955 compounds targeting LRRK2-a protein linked to #ParkinsonsDisease. pubs.acs.org/doi/10.1021/ac…

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Target 2035 retweetledi

Chemical Probes Portal@Chemical_probes·21 Kas

🚨 New publication alert! 🚨 Our latest update on the Chemical Probes Portal is live! 🎉 📜 Read the paper: doi.org/10.1093/nar/gk… 🔍 Learn about our expanded content + improved functionality in the 2024 Nucleic Acids Research Database Issue. #ChemicalProbes #BiomedicalResearch

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Target 2035 retweetledi

RSC Medicinal Chemistry@rsc_medchem·5 Kas

📢RSC Medicinal Chemistry is delighted to announce our newest Associate Editor, Dr Susanne Müller-Knapp from @goetheuni! 📰Read our blog for more about Susanne: blogs.rsc.org/md/2024/10/21/… 👀Submit to her today: mc.manuscriptcentral.com/mcc @Chemical_probes @thesgconline

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Target 2035@target2035·12 Kas

Just Launched! Episode 1 of the Target 2035 Podcast Series🎧 In the debut episode, @LabScribbles welcomes @CherylArrowsmi1, a leading scientist in chemical biology and one of the initiators of Target 2035. podcasters.spotify.com/pod/show/targe… #Target2035 #OpenScience #DrugDiscovery

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Target 2035@target2035·25 Eki

🎙️ The Target 2035 podcast series is officially LIVE! In our pilot episode, meet our hosts - @MilkaKostic, @LabScribbles and Opher Gileadi who share their personal motivations for joining the Target 2035 initiative. Tune in to the pilot episode now! podcasters.spotify.com/pod/show/targe… 🎧

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Target 2035@target2035·16 Eki

🎙️ Get ready... Something BIG is coming from Target 2035! What if the future of drug discovery could be unlocked by listening in? @LabScribbles, @MilkaKostic and Opher Gileadi got something brewing, and trust us- you won’t want to miss it! #Target2035, #OpenScience, #ComingSoon

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Target 2035 retweetledi

Keith Hornberger@KRHornberger·28 May

The short history of NSD2 degraders has been a little fuzzy with some odd mechanisms of action so far, but this one seems a little cleaner and more potent than its forebears. pubs.acs.org/doi/10.1021/ac…

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Target 2035 retweetledi

Keith Hornberger@KRHornberger·27 May

This is a terrific and comprehensive review on molecular glues from the Arkin lab. Open access too. cell.com/cell-chemical-…

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Target 2035@target2035·28 May

#affinity_selection #hit_finding #drugdiscovery

Structural Genomics Consortium (SGC)@thesgconline

Our ASMS platform is now officially up and running! @HalabelianLab and Hui Peng, with the support of the @InnovationCA, have completed the first round of ASMS screenings for 8 proteins in just 2 weeks, including thorough hit verification. Stay tuned for more exciting data!

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Target 2035 retweetledi

Ryan Potts@pottslab·6 May

Nice work from Gray and @fischerlab1 labs on combinatorial libraries for CRBN molecular glue discovery that yielded a WEE1 degrader. biorxiv.org/content/10.110…

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Target 2035 retweetledi

BryanRoth@zenbrainest·12 Mar

Wow!! Congratulations @BShoichet and others.

Membrane Protein PDB@MemProtPDB

Structure-based discovery of CFTR potentiators and inhibitors | bioRxiv biorxiv.org/content/10.110…

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Target 2035@target2035·11 Mar

Need a #chemicalprobe? @chemical_probes has reached 1000 chemical tools that have been reviewed by #drugdiscovery experts.

Structural Genomics Consortium (SGC)@thesgconline

Kudos to @Chemical_probes for reaching 1,000 compounds! A great collaboration with @target2035 to expedite chemical probe discovery.

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Target 2035@target2035·15 Oca

#AstraZeneca publishes on the challenges and impact on developing #highthroughput #thermalshift based #drugdiscovery High-throughput differential scanning fluorimetry (DSF) and cellular t... sciencedirect.com/science/articl…

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Target 2035 retweetledi

Structural Genomics Consortium (SGC)@thesgconline·16 Eki

Stefan Knapp and Susanne Muller talk about how different stakeholders can contribute to high-quality research using small molecule tools. nature.com/articles/s4158…

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Target 2035 retweetledi

Structural Genomics Consortium (SGC)@thesgconline·20 Eyl

We are happy to share that @target2035 will be featured in the upcoming @ChemBioSociety 2023 with a scientific session chaired by @CherylArrowsmi1. Among the speakers will be our very own @mattschap and Serah Kimani from @HalabelianLab. More details: chemical-biology.org

International Chemical Biology Society@ChemBioSociety

🔬 Join us at #ICBS2023 for a special scientific session featuring @target2035, a global open science movement with to develop a modulator for every protein in the human proteome by 2035. Sponsored by @EUbOPEN. More details: chemical-biology.org

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Target 2035@target2035·19 Eyl

A recent review by Edelris and AstraZeneca on "Affinity selection mass spectrometry speeding drug discovery" pubmed.ncbi.nlm.nih.gov/37660985/

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Keşfet

@MilkaKostic @aledmedwards @goetheuni @Chemical_probes @thesgconline @LabScribbles @CherylArrowsmi1 @fischerlab1