Hoo@Hoostethics
what makes aspirin a powerful anti-aging tool is also what might make it risky
and it starts with 𝙨𝙚𝙧𝙤𝙩𝙤𝙣𝙞𝙣…
95% of serotonin is outside the brain, made in the gut & stored in platelets
(cells that rush to injury sites to prevent bleeding)
when you’re stressed, injured or unhealthy - platelets activate & serotonin is released into tissues
𝙘𝙤𝙣𝙨𝙚𝙦𝙪𝙚𝙣𝙘𝙚:
> vasoconstriction
> inflammatory signalling
> fibrosis potential
now, aspirin’s main benefit for longevity is that it actually inhibits the aggregation of those platelets
but what cost?
first, 𝙡𝙚𝙩’𝙨 𝙩𝙖𝙠𝙚 𝙖 𝙡𝙤𝙤𝙠 𝙖𝙩 𝙧𝙖𝙮 𝙥𝙚𝙖𝙩’𝙨 𝙥𝙝𝙞𝙡𝙤𝙨𝙤𝙥𝙝𝙮 again…
he believed that aging is simply the accumulation of inflammation, fibrosis & stress signalling
he also viewed serotonin outside the brain NOT as the ‘happiness chemical’ doctors say it is
but rather a biological stress signal.
so in that case
𝙖𝙨𝙥𝙞𝙧𝙞𝙣 𝙞𝙨 𝙥𝙧𝙤 𝙖𝙣𝙩𝙞-𝙖𝙜𝙞𝙣𝙜 𝙞𝙣 𝙩𝙝𝙚 𝙨𝙚𝙣𝙨𝙚 𝙞𝙩:
> lowers serotonin signalling
> reduces inflammatory prostaglandins
> has anti-fibrotic effects (scar tissue)
> improves oxidative metabolism
> increases energy
> tightens the skin
the problem is platelets are essential in preventing bleeding & repairing tissues
and aspirin suppresses them irreversibly for their 7-10 day lifespan until new ones generate…
confusing right?
𝙡𝙤𝙬𝙚𝙧𝙞𝙣𝙜 𝙥𝙡𝙖𝙩𝙚𝙡𝙚𝙩 𝙖𝙘𝙩𝙞𝙫𝙞𝙩𝙮 𝙢𝙚𝙖𝙣𝙨 less clotting & inflammation but could also mean higher bleeding risk in some?
the keyword is SOME…
this is where bloodwork, healthy history & age are really important
no supplement is a one size fits all…
𝙥𝙤𝙨𝙨𝙞𝙗𝙡𝙚 𝙬𝙖𝙮𝙨 𝙩𝙤 𝙢𝙞𝙩𝙞𝙜𝙖𝙩𝙚 𝙖𝙨𝙥𝙞𝙧𝙞𝙣’𝙨 𝙨𝙞𝙙𝙚 𝙚𝙛𝙛𝙚𝙘𝙩𝙨 & 𝙨𝙩𝙞𝙡𝙡 𝙡𝙚𝙫𝙚𝙧𝙖𝙜𝙚 𝙞𝙩 𝙛𝙤𝙧 𝙡𝙤𝙣𝙜𝙚𝙫𝙞𝙩𝙮:
> avoid stacking with other blood thinners
> avoid using aspirin as a compensator for poor health habits
> always take with food to reduce gut irritation
> consider taking vitamin k/glycine/collagen to protect gut lining
> do not use if you have a history of ulcers or you bruise easily
as a young healthy person, i dont see the need to take aspirin as frequently as an older person with more inflammatory markers & cardiovascular risk.
my protocol:
> 150-300mg once per week max, with food
i notice a significant cognitive boost & de bloating effect in the face.
not medical advice.
