Carlos Thiene Pachón

Why would evolution create a nerve that stops the heart? 🤔 700 million years of answers, now in one book. 📚 "Cardioneuroablation A Comprehensive Guide From the Creators" The first complete guide by Pachon, Pachon & Pachon. 🧠 AF-Nest & spectral analysis ⚡ Vagal denervation step-by-step 🫀 Pacemaker-free solutions Foreword: Prof. Josep Brugada 👉 amazon.com/dp/B0G3HNRZYH #EPeeps #CardioTwitter #Cardioneuroablation #AFib #HeartRhythm

Something weird is happening with AI usage limits. Both my OpenAI and Anthropic usage meters returned to 100%, and about R$1,000 in credits appeared on my Anthropic account. Here’s what I observed and what’s public. 🧵 @lucas_montano

@rom1trs VOX

I built a Claude skill that makes Vox-style ads > writes the voice-over > breaks the ad into clips with timestamps. > Recreates the video with Arcads MCP in Claude Comment "VOX" and I'll send you the skill

@aakashgupta @zesaid

This is wild. SpaceX now has the right to BUY Cursor for $60B. Or pay them $10 billion to walk away. To put it in perspective, Cursor was worth $9.9 billion total in May of last year. Let's have a closer look at the numbers. Start with the $60 billion. Cursor was already raising money this week at a $52 billion valuation from a16z and Nvidia. The Elon offer sits 15% above a number that was already on the table. The next round priced in, with a one-year fuse. The $10 billion is the real number. That's what SpaceX pays even if it walks away and never buys the company. The walk-away fee alone is more than the entire company was worth 12 months ago. Now the strategic logic. Cursor stopped being just an editor in March. They shipped Composer 2, their own model, and it beat Claude Opus 4.6 on Terminal-Bench at one-tenth the price. The catch is that frontier coding models need frontier compute, and the only labs with frontier compute are the same ones building competing coding products. OpenAI shipped Codex. Anthropic shipped Claude Code. Google has Gemini CLI. Cursor was renting capacity from every company trying to kill it. Colossus is the way out. 230,000 GPUs in Memphis today, 1 million by year end, the biggest training cluster on Earth. The Information already reported Cursor is renting tens of thousands of those chips to train Composer 3. SpaceX is also building Grok Code, so they're not a clean partner. But xAI losing the coding race to Cursor is a better outcome for SpaceX than Cursor losing the coding race to OpenAI. The trade Cursor made: gave up the right to be acquired by anyone else for one year. Got training compute at a scale no other lab would sell them. Got $10 billion guaranteed if Elon walks. OpenAI tried to buy Cursor in early 2025 and got rejected. Cursor stays independent for at least 12 more months and gets to train on the biggest cluster on earth doing it. Elon just bought a one-year call option on Cursor for $10 billion. That's the deal.

Clinicians using Claude for research: heads up. Opus 4.7 has a dangerous pattern. It tells you it analyzed your paper, but often substitutes training knowledge for actual data extraction. The report looks great. The fidelity to your source? Not guaranteed. Opus 4.6 read what you gave it. 4.7 sometimes pretends to. For medical data analysis, this is a dealbreaker. A confident wrong summary of a clinical trial is worse than no summary at all. Verify everything. @AnthropicAI, please fix this. The platform is too good to lose trust over silent shortcuts. @lucas_montano

Our paper on long-term outcomes of cardioneuroablation with and without extracardiac vagal stimulation (ECVS) confirmation was recognized as a Top Cited Article 2025 by @WileyHealth in the Journal of Cardiovascular Electrophysiology. ECVS, developed by our group over 10 years ago, as a procedural endpoint makes a measurable difference in outcomes. Grateful to our coauthors and the SEMAP/hcor team. @JCardioEP #cardioneuroablation #Syncope #NeurocardiogenicSyncope @WileyGlobal #EPeeps #CardioTwitter #Electrophysiology #Cardiology onlinelibrary.wiley.com/doi/full/10.11… #TopCitedArticle @wileyinresearch @PachonMateos @Pachon_CNA

🫀 Did you know that cardioneuroablation was born from the study of atrial fibrillation? While studying AF in structurally normal hearts, Dr. Pachón discovered AF-Nests. When ablated, the atria became more stable... but vagal response was also abolished. 💡 The insight: We found a way to map the neuromyocardial interface! What if we could use this to treat vasovagal syncope instead of implanting a pacemaker? That's how CNA was born! This journey, from discovery to clinical application, is detailed in our book 👆 #EPeeps #CardioTwitter #Electrophysiology #Cardioneuroablation #AFib

Why would evolution create a nerve that stops the heart? 🤔 700 million years of answers, now in one book. 📚 "Cardioneuroablation A Comprehensive Guide From the Creators" The first complete guide by Pachon, Pachon & Pachon. 🧠 AF-Nest & spectral analysis ⚡ Vagal denervation step-by-step 🫀 Pacemaker-free solutions Foreword: Prof. Josep Brugada 👉 amazon.com/dp/B0G3HNRZYH #EPeeps #CardioTwitter #Cardioneuroablation #AFib #HeartRhythm

The book covers 15 chapters including: fluoroless CNA, complications, and the comparison between pacemaker vs cardioneuroablation for vasovagal syncope.