Third Wave

We often ask whether or not psychedelics “work. What if this misses the point entirely? A deeper take from Justin Smith-Ruiu on medicalization and culture. Full episode with @paulaustin3w: youtu.be/lc2L8KwYbGw

Jay Campbell explains why compounds like OS-01, an AMP kinase stimulator, are getting attention for their potential to support metabolism, energy production, and fat utilization. Watch the full episode: youtube.com/watch?v=od4tLT…

What does a psychedelic church actually look like day to day? In this episode, Paul Ryder speaks about community, minister training, and why ceremony is only one part of the work. Full episode with @paulaustin3w: youtu.be/uJFXAaUTTwQ

Ketamine is often grouped with psychedelics… but it’s a very different compound. From dissociation to tolerance and shorter-lasting effects, the distinctions matter. Watch the full video with @paulaustin3w: youtube.com/watch?v=_G2nNy…

Most people think psilocybin works through chemistry alone. But the deeper shift is pattern disruption → new choices → better regulation. Watch the full video with @paulaustin3w: youtube.com/watch?v=WiBjIW…

Sometimes the belief becomes: “I need another journey to access this.” But what if the real shift comes from learning to stay with what’s already here? Full episode with @paulaustin3w: youtube.com/watch?v=_s3otY…

People think you’ll just “do IFS” in a psychedelic state… but it’s not a therapy session. It’s a way of relating to parts, even when they’re activated or resisting. Full episode with @paulaustin3w: youtu.be/_s3otYDbC14

What if end-of-life care addressed more than physical pain? A single psilocybin session may help patients step out of loops of anxiety and see their life in a wider frame. Watch full episode: youtu.be/DqSDCm5fUqk

Many veterans first encountered ibogaine through addiction recovery. Now, researchers are exploring its potential for traumatic brain injury and blast exposure. Featuring @terragnosis with @paulaustin3w Full episode: youtube.com/watch?v=aamyya…

What happens when culture, religion, and policy start to shift around psychedelics? From The Psychedelic Podcast #352 with @paulaustin3w Watch the full episode: youtu.be/qQUGhLLyIMw

What if healing mattered more than the law? Laura Dunn shares why she risked everything to access trauma healing, and why she believes those laws must change. Watch the full video with @paulaustin3w: youtu.be/qQUGhLLyIMw

Microdosing and macrodosing aren’t isolated tools. In this clip, @paulaustin3w explains how microdosing high-dose journeys can work together as part of a coherent coaching framework. Watch the full video: youtu.be/uQ7b8nCNYC4

Ketamine isn’t a classic psychedelic… and treating it like one may explain why people keep returning to it. From: The Problem With Treating Ketamine Like a Psychedelic Featuring @PaulAustin3w Watch the full video: youtu.be/_G2nNypTORI

What if preparation for a psychedelic journey starts by listening to the parts of you that feel resistant? J. Ashley T. Booth explains why low-dose work can help protector parts feel safe enough to participate. Full episode: youtu.be/38Bljl_vNbU

What’s shaping ibogaine treatment today isn’t just research… it’s real demand from veterans and patients. Jonathan Dickinson on how practice is evolving in real time. Full video with @paulaustin3w: youtu.be/aamyya7leKY

SSRIs and psychedelics aren’t opposites. Both act on serotonin. One stabilizes. The other creates controlled disruption. The 5-HT2A “gate” helps explain why some meds can blunt LSD and psilocybin effects. Full video with @paulaustin3w: youtu.be/Oq_DGa_MVvU

11 million Americans have tried psilocybin mushrooms in 2025. The urge to tell everyone after a big experience is predictable… but integration takes time. Watch the full video with @paulaustin3w: youtube.com/watch?v=XkC3-r…

We spend a third of life dreaming… yet dismiss it as unreal. Justin Smith-Ruiu highlights a contradiction in Western philosophy: we trust sober perception, even though we can’t prove it reflects reality. Full episode with @paulaustin3w: youtu.be/lc2L8KwYbGw

Longevity isn’t just about biomarkers. Perceptual flexibility changes how people relate to food, stress, movement, and connection. Over time, that’s what shifts the data. Full video with @paulaustin3w: youtube.com/watch?v=WiBjIW…

Cannabis isn’t what it used to be. Higher potency + less moderation is changing the experience in ways most people don’t expect. From The Psychedelic Podcast #348 with @shaahincheyene Watch: youtube.com/watch?v=Ph3cf8…