Thyroid Journal

NEW pilot-grant program! 🔬 ATA is funding 15 early-career investigators with up to $10K for innovative thyroid research. Applications due May 15. Associate & Early Career Members—this is your opportunity! Apply: ow.ly/TRGv50YR6bF #ThyroidResearch #ResearchGrant #ATA

How can we measure quality of life in thyroid cancer survivors? A new @ThyroidJournal study introduces the TCQOLI—a validated, thyroid-cancer–specific utility index designed for QALY estimates, cost-effectiveness analyses, and patient-centered decisions. ow.ly/3UIK50YIi1o

Does levothyroxine benefit older adults with subclinical hypothyroidism? In the Emulated Target Trial of >22,000 UK patients, authors from @sunderlanduni report lower CV events & all-cause mortality with LT4—esp. when TSH exceeded age-specific ranges. ow.ly/3lXm50YEFfF

What are risks of permanent hypoparathyroidism after thyroidectomy? Recent study from Korea found higher rates of kidney stones, renal insufficiency & major cardiac events in patients with PO-hypoPT—highlighting need for ongoing renal & CV monitoring. ow.ly/kSFS50YEEPf

Can neonatal fragment crystallizable receptor (FcRn) blockers assist in treatment of refractory Graves’ disease? New @ThyroidJournal case report describes rapid normalization of thyroid hormones wi/batoclimab & sustained euthyroidism after stopping therapy ow.ly/3y4s50Yx3gJ

New options for BRAFV600E-negative anaplastic thyroid cancer? In a phase 2 @ThyroidJournal trial, anlotinib + sintilimab achieved a 48% response rate & median PFS ~9.6 months, with manageable toxicity—supporting further study. ow.ly/ICpy50Yx35s #ThyroidJournal #medtwitter

When tumor tissue isn’t available in sporadic MTC, can liquid biopsy help? A @ThyroidJournal study shows plasma ctDNA reliably detected RET mutations in progressive, high–tumor burden cases—supporting its use to possibly guide RET inhibitor therapy. ow.ly/aX0Y50Yx2Pe

The March issue of @ThyroidJournal is now available online! ow.ly/fHpN50Yx0Vi #AmericanThyroidAssociation #ATAthyroid2026 #ThyroidJournal #endotwitter #medtwitter

How do BRAFV600E & TERT cooperate in aggressive thyroid cancer? A new @ThyroidJournal study identifies DDX21 as the molecular link—upregulated via MEK/ERK/GABP, interacting with TERT to drive rRNA transcription and tumor progression. ow.ly/e1M150Ys4Bi @AmThyroidAssn

How do patient beliefs shape experiences after radioiodine? A new @ThyroidJournal prospective study found poor recall of required precautions, frequent self-imposed restrictions & reported side effects—often linked to pre-treatment beliefs. ow.ly/CLjf50Ys4m2

Is AI transforming thyroid cancer diagnosis? 2026 update @ThyroidJournal reviews FDA-cleared tools for ultrasound, emerging platforms for lymph nodes & pathology & key considerations for implementation—IT, usability, effectiveness, vendor support & cost. ow.ly/Bjpm50Ys3PJ

How do patients decide on surgery for low-risk #thyroidcancer? A @ThyroidJournal study found shared decision-making hinges on tailored info, desire to limit surgery/avoid lifelong hormones & clinician recommendations- guiding better decision-support tools. ow.ly/TKaM50Ys3ht

What is the risk of hypothyroidism after hemithyroidectomy in children? What if you carry TPO antibodies? New study from @BostonChildrens who found ~28% develop persistent hypothyroidism with higher risk if TSH ≥2 and + TPO antibodies. ow.ly/gtUq50Y1TpW @AmThyroidAssn

Can unstimulated thyroglobulin predict recurrence after thyroidectomy without RAI? A team from Korea studied nearly 10,000 patients & found Tg cutoffs (≥0.2 and ≥5.0 ng/mL) and rising Tg over time strongly predicted structural recurrence ow.ly/WkZU50Y1TfP @AmThyroidAssn

Can #ALK inhibition improve outcomes in ANAPLASTIC thyroid cancer? New study from Germany using an ALK-driven, p53-loss ATC model showed ALK inhibitors suppressed signaling & markedly prolonged survival—supporting ALK as a therapeutic target in #ATC. ow.ly/ALov50Y1Tar

Does teprotumumab reduce the need for further treatment in TED? New @ThyroidJournal study found similar treatment rates vs IV steroids. IVMP led to more complex, multi-step care, while teprotumumab simplified treatment pathways ow.ly/fQaE50Y1SJ5 @AmThyroidAssn #medtwitter

Can subcutaneous levothyroxine help with severe oral malabsorption? New report from Singapore showed excellent absorption— approx 9× oral bioavailability—with rapid TSH normalization, supporting SC levothyroxine as effective alternative. ow.ly/BC3f50Y1SoQ @AmThyroidAssn

Does weight gain after treating hyperthyroidism affect quality of life? A new @ThyroidJournal study found post-treatment weight gain was linked to worse QoL, highlighting the need to address weight changes in care. ow.ly/p8MQ50Y1RV9 @AmThyroidAssn #medtwitter #endotwitter

Does hypothyroidism affect mortality risk? Does it matter if it is overt or subclinical? An association was found with both in a new large Chinese cohort study which investigates this association in @ThyroidJournal. ow.ly/boQ550XSIfe @AmThyroidAssn #medtwitter #endotwitter

Does thermal ablation improve quality of life for benign thyroid nodules? New meta-analysis by @UMmedschool in @ThyroidJournal suggests QOL often improves, results vary by domain & study heterogeneity limits comparability. ow.ly/c9L550XSEmv @AmThyroidAssn #medtwitter