Brad Turner

Australian research finds promising triple-drug combination for motor neuron disease irishnews.com/news/world/aus…

Combinations - all the cool kids are doing them! New research from @turnerMNDlab @TheFlorey & collaborators present patient-derived iPSC models of #ALS that identified baricitinib + memantine + riluzole as a promising potential therapeutic combination nature.com/articles/s4159…

Large-scale drug screening in iPSC-derived motor neurons from sporadic ALS patients identifies a potential combinatorial therapy nature.com/articles/s4159…

We gratefully acknowledge the generous support of @FightMND, @VicGovAu, Balcon Group, MRFF and Stafford Fox Foundation. This publication is dedicated to the memory of our colleague, Dr Ian Davis OAM, Co-Founder of FightMND, whose memory and legacy continue to inspire our research

This work was a wonderful collaboration with @AlicePebay @AlexWHewitt and team @EyeResearchAus; @WrayNaomi @FleurryG and team @IMBatUQ; Sue Fletcher @MerrileeNeedham @MurdochUni and @locusJ @UNSW, alongside many others @Florey @UniMelb @latrobe @neuraustralia @NDCNOxford

Thrilled to share our study out in @NatureNeuro today! nature.com/articles/s4159… A mammoth effort with Chris Bye @TheFlorey to build the largest #MND #ALS patient iPSC library in Australia, paired with comprehensive clinical and multi-omic profiling.

Team MND from the @TheFlorey at #PACTALS2025 Melbourne. Showcasing our latest research excellence and clinical advances in #MND #ALS with our colleagues from the Asia-Pacific region 🧬🧫🧠🩺

Cortical hyperexcitability drives dying forward amyotrophic lateral sclerosis symptoms and pathology in mice sciencedirect.com/science/articl…

@liebscher_lab Thank you for your kind post on our paper. Building on your great work and others!

Good to see this finally out. This is very important work for the ALS field demonstrating a link between aberrant neuronal activity in motor cortex and TDP-43 pathology. It emphasizes the critical role of cortical dysfunction in ALS. Congratulations to the entire team!

Cortical #hyperexcitability drives degeneration of #neurones, axons & synapses; with subsequent degeneration of neuromuscular junctions causing muscle denervation | Validation that cortical hyperexcitability leads to #TDP43 in central & peripheral neurones | #ALS #MND @magxite

Very proud of this work and fantastic collaborative effort! @TheFlorey @neuraustralia @nervecentrals @WolfVucic @MonashBDI @MAPP_latrobe @FightMND @MND_RIA sciencedirect.com/science/articl…

Thrilled to publish our work using cortical hyperexcitability induced by chemogenetics in vivo to drive #ALS #MND symptoms and pathology. Strong support for a pathological role of cortical hyperexcitability in ALS and a dying-forward mode of neurodegeneration 🧠 …

Our paper about how autophagy changes in mice as they age is now available at @PLOSONE ! Big thanks to @TimSargeant1 , @turnerMNDlab & team, as well as @sahmriAU , @uniofadelaide & @hosp_research ! journals.plos.org/plosone/articl…

Great to attend the ALS Modeling workshop on iPSCs in Washington DC co-organised by @packardcenter and @ProjectALSorg. 2 days of intense debate and discussion of key challenges and innovations in iPSCs. Great insights from the best minds in the field. Plus the sights of DC! 🧫🧬

@LeighWalkerPhD @NatureComms @RobynBrownLab @willgiardino @feliciamreed1 Wow! Huge congrats Leigh to you and your team! 👏👏

Check out our new paper lead by superstars Amy Pearl and Xavier Maddern in @NatureComms We show a sex specific role for ghrelin signalling in the Edinger Westphal nucleus driving binge drinking. Thanks @RobynBrownLab @willgiardino @feliciamreed1 nature.com/articles/s4146…