Vincent de Boer

@rickwierenga Wow, this is so great!

claude is independently connected to a plate reader and writing a PyLabRobot interface to it

lots of updates to the cytation5 (and thus cytation 1) backed today!

Gotta extract some PBMCs? Or run a Seahorse cell metabolic analysis? @vcjdeboer lab’s Portfolio is a goldmine of protocols 🔥 Based at 🇳🇱 Wageningen University, they study the inner workings of mitochondria and how mitochondrial metabolites communicate with epigenetic machinery. Check it out here 👇app.briefly.bio/portfolio/vinc…

images taken with PLR and Cytation5 (brightfield, phase contrast, gfp) #imaging" target="_blank" rel="nofollow noopener">docs.pylabrobot.org/user_guide/cyt…

@immunometlab @RyanLab_MBU @laoneill111 @KeystoneSymp Those days were great Jan, nice and clean data indeed!📊😀🥂

@RyanLab_MBU @laoneill111 @KeystoneSymp So nice and clear that it converted @vcjdeboer (who taught me how to use the Seahorse back then🙏) to also study macrophages 😇

The rise of immunometabolism research over the past decade according to @laoneill111 Fun fact; the first immunometabolism experiment we did was in 2013 and was inspired by a @KeystoneSymp talk by the same Luke O’Neill

Excited to have this great collaborative effort on human SIRT5 variants published in iScience! Human SIRT5 variants with reduced stability and activity do not cause ... sciencedirect.com/science/articl…

@DonMostrenco Thanks @DonMostrenco, that’s a great read, with relevant messages: “But here is the thing about science: it thrives on serendipity. If all risks had been averted and all processes duly followed, it is unlikely that we would have seen these three mindblowing dissertations.”

cc @vcjdeboer, we were talking about academic writing styles past week. I'm sure the blogpost above will feel like fresh oxygen to you as it did to me.

Academic writing in general, and doctoral theses in particular, are known for their arid, almost anti-human style. This wonderful piece by @DingemanseMark reminds us it is not mandatory to be boring. ideophone.org/mindblowing-di…

@JosiahParry I think the locator function might be useful. Was used here: stackoverflow.com/questions/5757…

📃Functional and molecular profiling of fasted piglets reveals decreased energy #MetabolicFunction and #CellProliferation in the small #intestine (Anna F. Bekebrede et al.) ow.ly/SFNH50Qp0Eg @vcjdeboer #fasting #mitochondria #ajpgi

From open science infrastructure to a national training platform for data stewards, and from investments in sustainable open research software to Citizen Science Hubs. We are very pleased to announce our first work programma for 2024-2025. Read more: openscience.nl/en/news/open-s…

🆕 in the #AJPEndoMetab March issue! 👉 Impact of tyrosine kinase inhibitors on glucose control and insulin regulation in patients with chronic myeloid leukemia (Janssen et al.) ow.ly/4YSp50Nogk0 @Radboud_Uni #chronicmyeloidleukemia #glucosemetabolism

…. and more to come

Joëlle Janssen successfully defended her thesis on Wednesday, great discussions on Metabolic mapping and measuring mitochondria in pbmcs and muscle with committee members; prof Witkamp, prof Serra Vich, Dr. Wopereis and @immunometlab

Excited to share our work @kiran_r_patil in @ScienceAdvances! The mammalian nucleus harbors extended metabolic network made of parts of the TCA cycle providing a spatial dimension in the coupling of metabolism to chromatin, RNA and protein modifications science.org/doi/10.1126/sc…

Extracellular flux analyses reveal differences in mitochondrial #PBMC metabolism between high-fit and low-fit females; new #TranslationalPhysiology #ResearchArticle: ow.ly/cBU150HMzYE #lifestyle #biomarker #aerobicfitness