Turlier lab

How can we learn tissue mechanics directly from patterns and images? In our new preprint, we introduce VertAX, a differentiable vertex-model framework in JAX for simulating epithelia, inferring parameters, and designing target tissue behaviors. shorturl.at/PUzT0 1/5

A true computational tour de force by Eric Neiva during his Marie Skłodowska-Curie postdoctoral fellowship in the team, now published in Journal Computational Physics: urlr.me/AuzK86 Congratulations, Eric! @CNRSbiologie Grateful to @EU_Commission for funding support

We hope VertAX can help make inverse problems & differential programming more accessible in tissue mechanics. Thanks to @appasqui, @MaxenceErnoult, Italian colleagues, & other members of the team for this collaboration. Comments very welcome. Code github.com/VirtualEmbryo/… 5/5

Beyond synthetic benchmarks, we show applications to mechanical parameter inference from microscopy images and to inverse design problems in epithelial tissues. 4/5

How can we learn tissue mechanics directly from patterns and images? In our new preprint, we introduce VertAX, a differentiable vertex-model framework in JAX for simulating epithelia, inferring parameters, and designing target tissue behaviors. shorturl.at/PUzT0 1/5

If you think the next big idea in your field will come from inside the field, you're probably wrong.

Conference Alert🚨 16-21 Feb 2025 From Soft Matter to Biophysics @ Les Houches FR t.ly/GXhPL Apply by Dec 15 to explore the latest in soft matter & biophysics, focusing on functional materials & synthetic biology! @karen_alim @Karin__Jacobs @MartinLenz @HerveTurlier

Registrations are open for the Qlife Quantitative Biology spring school on Cell Dynamics in Developmental System March 3-April 04 2025. Great line of talks, lectures and hands-on practicals on omics, image analysis, modeling and inference: shorturl.at/Ygthh

Team retreat in the Pyrenees 📝⛰️🍻

We recapitulate our findings in a mathematical model and show that this creates a feedback loop, where the front and back communicate through mechanical signals. @virtual_embryo @andreu_gallen It ensures that the cell can move forward in a coordinated way.

Thanks to all speakers @MarinoArroyo2 @AnjaGeitmann @AlainGoriely Jessica Zhang @aland_lab @GabriellaBioMec Arezki Boudaoud Christophe Godin, Brendan Lane, Robert Nürnberg, Padmini Rangamani, Arnold Reusken, Axel Voigt, Sara Zahedi, Roman Vetter

Our workshop on Finite Elements for Cell & Tissue Morphogenesis at Villa Clythia @caescnrs was a great success ! Congratulations to @ericnumerics for the perfect organisation and looking forward to a next edition.

@HerveTurlier @cavankatenaugh @CharrierLab @sneha_arao @LenartLab @Vane_barone @Chema_MD @sdebuyl @Alex_Mc_Dougall @HitoyoshiYasuo

Our workshop on early embryo morphogenesis in Villefranche-sur-mer was a blast 💥 Thanks to all participants for the lively & friendly atmosphere, @RDumollard for co-organising and to @biodev_vlfr for the great welcome & fantastic setting. Looking forward to see you all again !

Some action shots from an amazing week in Villefranche-sur-mer. Thanks to @virtual_embryo and @RDumollard for pulling together some incredible minds (and microorganisms). Here is proof that there was actually some science happening!

An interesting perspective article in Nature by @eisensteinium on the forces that sculpt embryos and how to measure them, highlighting our 3D tension inference method foambryo by @SachaIchbiah & @HerveTurlier nature.com/articles/d4158…

A huge congratulations to @ap_pasqui for 1st prize in the @eelisa_eu student scientific competition in the Chemistry and bioengineering category. Well-deserved! More about the competition tinyurl.com/4uhfmf7a

Great scientific discussions and insightful perspectives across biology & AI at the Fondation des Treilles, with wonderful colleagues @VirginieUhlmann @KrishnaswamyLab @MOSAICgroup1 @loicaroyer @ky396 @decbaycomp @will_prew @desi_ramram @martweig V. Vitelli, H. Isambert, C. He

We extended the deadline for abstract submission for young speakers to May 13 !! This is the final deadline