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@thedevchandra see profile ser ty

Let's do something fun today: Roasting landing pages. Drop yours, will roast as many as I can.

what to do now?

@m_goes_distance lmaooooo

A rich friend of mine finally decided to take his longevity seriously. We all expected him to go full Bryan Johnson. Red light panels, CGM, the whole stack. He shows up to the biohacker meetup with a Whoop, AG1, and a $400 supplement protocol he found on a wellness influencer's page. My friend hits me with the funniest line: "I get the vision, but not the execution." This is a metaphor for 90% of the longevity industry. The science exists. Epigenetic reprogramming, senolytics, peptide protocols that actually move the needle. Instead we get $79 greens powder with $11 of ingredients and a podcast. I get the vision. But not the execution.

@m_goes_distance scifi vibes lately

everything that felt offensive in science is starting to feel normal baseline is going to look very boring in 12-18 months.

@jaredsuniverse walletchat, welcome

If you're bootstrapping a startup and posting about it on X, congrats - we’re officially friends now Drop your project below for honest feedback.

@m_goes_distance lol obese is what?

this is just insane! what do you mean "obese" is offensive and "fat bodied" is not? last I checked: "obese" = clinical term that flags a health risk "fat bodied" = language that feels less judgmental we’ve reached a point where facts are considered rude and denial is compassionate now? you don’t have to be perfect, but at least DON'T LIE TO YOURSELF.

@kzitouni1 ah yesssss

Anti-slop must watch films for every founder who discerns great taste: >Helvetica >The Social Network >Moneyball >Steve Jobs >BlackBerry >The Founder >Margin Call >The Big Short >Inside Job >Enron: The Smartest Guys in the Room >WeWork: Or the Making and >Breaking of a $47 Billion Unicorn >Jiro Dreams of Sushi >Abstract: The Art of Design >Objectified >Exit Through the Gift Shop >The Last Dance >Free Solo >Man on Wire >The Fog of War >Oppenheimer Welcome.

@m_goes_distance hey bro congrats on ur JRE appearance

>be me >somehow end up on Joe Rogan >thought we'd talk about AI, WW3, biotech or whatever >5 minutes in he's explaining his rapamycin microdosing protocol >pulls out a vial mid-podcast >"bro, I take this every other week, mTOR inhibition" >starts showing me his Oura ring data >then his biological age dashboard >he's 57, dashboard says 43 >casually mentions his doctor runs offshore trials in Honduras >"you want in on the next peptide study?" >Jamie pulls up Phase 1 data on the screen >it's actually promising >now we're 2 hours deep on senolytics and mitochondrial function >completely forgot what we were supposed to talk about Why does every podcast eventually become a longevity seminar?

@m_goes_distance heard theres a new secret biolab in sf

- touch down sf - coffee shop in Palo Alto - guy next to me tracking 47 biomarkers on his laptop - thought he was doing saas metrics - he's optimizing his methylation age - starts explaining his quarterly rapamycin protocol - pulls out a vial from his backpack - grey-market BPC-157 - bought on Telegram, mixed in his kitchen last night - offers me some like it's a mint - "bro, want to speed up tissue repair?" Why does this feel completely normal here?

@m_goes_distance LFGGG

most people have no idea what SUPERHUMAN FUND is. here's what we actually do: we back founders building the future of human biology. gene editing, longevity protocols, cellular reprogrammin, AI drug discovery, brain-computer interfaces, metabolic optimization, human 2.0 basically biotech stuff that sounds like sci-fi but is happening in labs right now. we are not chasing the next AI wrapper, we're funding the companies that will let humans live to 150, cure aging, and upgrade biology like software. currently qualifying LPs for Fund II which launches in Q2. if you believe humans can be better than baseline, this is for you.

@m_goes_distance yes lfgggg

It's genuinely insane how much progress biotech has made in the last 90 days: - Two years ago I watched Lucy Therapeutics shut down after 7 years and $42M from Bill Gates, never reached human trials. Last month DeSci crowdfunded €2.5M in 72 hours for Dr Barbacid cancer trials and went straight to human trials. Zero VCs and zero committees in the middle. And it's not even about the money. The goodwill - Gene therapy cost $2-4M per treatment a year ago because manufacturing was artisanal and nobody was actually solving it. Now automation's dropping costs toward $200. Turns out it was an engineering problem all along. - Just a year ago, the FDA wouldn't touch longevity. In January 2026, first FDA-approved human trial reversing cellular age launched (ER-100). We're testing age reversal in humans right now. Not mice. - Psychedelics stuck in regulatory hell for 50 years. In February 2026, Compass crushed Phase III for psilocybin in treatment-resistant depression. - In 2023, AI drug discovery was hype. $17B got invested, zero approved drugs. Early 2026, Ginkgo x OpenAI ran over 200k autonomous experiments, 36K of those were unique. Protein costs dropped by 40% and they're already shipping commercially. Discovery timelines collapsed. - Just last year, FDA required full GMP pre-Phase 2, moved at 1950s speed. This quarter,we're fast-tracking frontier therapies, relaxing requirements, launching pilots. Something shifted and the regulatory wall is cracking. - In 2024, clinical trials had to run in US at 2x cost, half the speed. Right now in Singapore and China running trials 50% cheaper, 2x faster. Companies routing around FDA entirely. The US model is optional. I could keep going on with these, but you realize that the bottleneck was never the science. It was funding models, regulatory speed, manufacturing, geography etc And most of them are breaking since last October. Biotech has shed 30 years of broken infrastructure in 5 months and I can't be more bullish. bio/acc.

@jaredsuniverse sf it is

@m_goes_distance @dranantmd this one was long overdue

GLP-1s may be the first real human enhancement drug. I interviewed @dranantmd on why they could be a wedge into longevity, next-gen peptides, programable biology, and AI-driven human upgrades. 0:00 - Health → Human Enhancement? 5:37 - GLP-1s: The Real Novelty 8:23 - Next Gen Drugs, Peptides 13:29 - Un*ucking Regulation 22:50 - Health Influencers & Hype 29:23 - Social Media vs AI Discovery 35:46 - GLP1s = Prozac? 41:35 - Biotech Is The Answer 48:19 - AI Drug Discovery

@m_goes_distance LFG RIDE

"unc, my quant says Superhuman Fund II is dropping in Q2 and we need to go all in on biotech and longevity NOW"

@thedevchandra acceletratorrrr

87 startup programs that'll give you up to $1,000,000+ in free resources - and you can apply right now. (We pulled $100k from just 5 of these) NVIDIA, AWS, Google Cloud, Microsoft Azure, Cloudflare · Stripe, Notion, Datadog · PostHog, Retool, Figma, HubSpot, Salesforce, Segment, Anthropic, OpenAI · GitHub, Slack, Intercom, Deel...etc I spent 3 months compiling these for our San Francisco founder community and figured it would help most of you. Want the full database? Like, follow and comment "ACCELERATE" and I'll send it to you FREE for 24 hours only.

@m_goes_distance its actually insa-

Holy shit what are we even doing man? Antidepressant prescriptions among teenage girls are up 129% since March 2020. can someone please explain to me like a 12-year-old why we're slamming adolescents with SSRIs in the name of "treatment" instead of fixing the basics first?

@thedevchandra do it

Might fool around and give away a founder's kit worth $50k in AI tools Everything from building your idea To launching your MVP And raising capital Let me know if this will help someone and I'll do it tomorrow.

@m_goes_distance bullish on bio/acc

biotech is bullish here's what happened in feb: 1. First custom gene fix for one patient - UNC Chapel Hill and Duke created personalized base-editing treatment for baby KJ's rare liver disease (gene therapy is now customizable per person) 2. Making cancer treatment inside patients - Interius BioTherapeutics & Kelonia starting Phase 1 trials manufacturing CAR-T cells directly in your body instead of in labs. Way cheaper and faster 3. AI invented a new gene editor - Profluent Bio's OpenCRISPR-1 designed entirely by AI, not found in nature .More precise than CRISPR, fewer off-target cuts 4. Human trials to reverse eye aging - Life Biosciences got FDA approval to test Yamanaka factors in human eyes for glaucoma (making human tissue biologically younger, starts Q1 2026) 5. Parents can now screen embryos for IQ - Orchid Health and Genomic Prediction offering polygenic screening for intelligence and height during IVF. MIT called it breakthrough tech of 2026 6. Big pharma buying actual cures - Gilead paid $7.8B for Arcellx's CAR-T therapy for multiple myeloma (shift from managing disease to curing it, FDA decision Dec 2026) 7. $315M for ALS research - US federal government historic funding for trials targeting TDP-43 protein . Patients being dosed now. if this pace holds, we'll make more progress in 2026 than the last 50 years combined. bio/acc.

@m_goes_distance yes

if we funded biotech more and avoided wars

@m_goes_distance the west might be cooked

China is spending $300M on weather control but America bans it out of fear? The West is cooked if this is how we respond to real tech. I interviewed the guy doing it anyway: Drones flying into clouds. Rainfall on command. Terraforming next. Pretty unhinged stuff. Link below.