Bruce Wang

Wingreen named 2026 Laureate of the Tel Aviv University International Prize in Biophysics, recognizing outstanding scientists whose work has significantly advanced the understanding of biological systems through physical principles. linkedin.com/posts/biosoft-…

@dbikard CBASS against JBD67∆acb from Erin Huiting, et. al, Cell 2023 from the @joeBondyDenomy lab. Fig. 2F: cell.com/cell/fulltext/….

Hello phage phriends. Do you have examples of anti-phage defense systems that were shown to tolerate lysogeny but target the phage when it enters its lytic cycle ? (beyond type III CRISPR: nature.com/articles/natur…)

Excited to share our work in the @bsadamson lab using prime editing for multiplexed dropout screens! We built a platform that can reach high-efficiency editing and tested 240,000 epegRNAs for phenotypes. We saw phenotypes we expected and a few we didn't - check here for details!

@HarmitMalik @netflix If you liked Pluto, Monster is also on netflix (by the same manga author) -- it's arguably considered his best work. Zom100 and Vinland saga are also pretty good stories!

So anime folks who’re in the know … is PLUTO the best thing on @netflix right now? What else should I watch? I’m also watching the latest season of Demon Slayer. Is there something as good as Deathnote that I should be watching?

Excited to share our work mapping the PARP inhibitor response network! We measured ~300,000 genetic interactions, describe the genome stability network, identify context-dependent GIs revealing unknown PARPi responses, and more—check here for details! biorxiv.org/content/10.110…

@OdedRechavi Most times more probes/less input RNA would probably work if your probes are designed for the particular species...

@OdedRechavi You could increase the ratio of probes/RNA, or you could also design new specific oligos for your organism of interest? NEB has a nice tool, depletion-design.neb.com with a kit that uses hybridization with DNAprobes + RNase H digestion: #Product%20Information" target="_blank" rel="nofollow noopener">neb.com/products/e7865…

RNA people: What do you do if ribo depletion doesn't work in a given organism?

@WallaceUcsf But, since Brownian motion has _stationary increments_ , it cannot be stationary unless the process is trivial: #3315356" target="_blank" rel="nofollow noopener">math.stackexchange.com/questions/3315…

@WallaceUcsf It shouldn't be based on "strict definition" -- the variance of Brownian motion depends on time. Maybe they are conflating "stationary process" with "stationary increments"? Stationary increments is true (B_t - B_s has the same dist as B_{t+k} - B_{s+k}).

Is Brownian motion a stationary process? I would think not, but im seeing contrary statements on the web, and I don’t get it. Help!

@TomJeon2 hi there tom