CMR
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CMR
@whyCMR
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Good question and interesting paper. 👇🏻 My 2 cents, Lp (a) is a marker more than a causal agent. I predict w low levels of conviction that Lp (a) lowering trials will be meh


📢 A practical approach to multimodality 📷 in HCM🫀 -from imaging targets and pitfalls to avoid to imaging-guided management. Check our review paper - link ➡️ mdpi.com/3264034 @MonteHeart @danilorenzatti @CardioMDPhD @AnkurKDalsania @SISIACOficial #ACCimaging

In the EPIC-Norfolk study (EHJ 2025, doi.org/10.1093/eurhea…), statin-induced Lp(a) rise (5–20%) increases CV risk by ~1–5% (absolute risk +0.2–1% over 20y). Yet, high-intensity statins reduce LDL-C by 50%, cutting CV risk by ~40–50% (absolute risk –15–20% over 20y). Conclusion: LDL-C lowering >> Lp(a) rise.







































