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A very important document jamanetwork.com/journals/jama/… also to follow up in the next years.
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werner muller
1.5K posts
werner muller
@wmuee
#Immunology who likes antibody sequence analyses, Emeritus Professor, University of Manchester,Inaugural Bill Ford Chair of Cellular Immunology, Spatial Biology
Katılım Ocak 2011
2.7K Takip Edilen976 Takipçiler
Blast server This URL seems still to work "blast.ncbi.nlm.nih.gov/Blast.cgi"
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I can not run a blast search on NCBI, the link blast.ncbi.nlm.nih.gov seems to be broken. Is this the first sign of data base breakdown or just a temporary glitch? Or there is a new web address I do not know yet?
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@sinabooeshaghi @lpachter Even big publication databases contain a lot of errors (some more some less) “supporting” halizunizations.
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If you work in AI for Science, take a moment to familiarize yourself with a common failure mode: paranormal citations (or paracites). Our paper describes them.
Lior Pachter@lpachter
AI hallucinations in science manuscripts are a nuisance. Paranormal citations, or paracites, will be a nightmare. biorxiv.org/content/10.648… (w/ @sinabooeshaghi & @NeuroLuebbert).
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@lpachter The new way, Import a GitHub Code and rewrite with safety Checks, with your favorite outputs.
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I am a computational biologist and I rewrite RNA-seq pipelines.
Sanjay Srivatsan@SRsrivatsan
Not sure why there’s push back here. Stockholm Syndrome? You don’t want bright people doing rote pipetting in the same way you don’t want computational biologists to rewrite RNA-seq pipelines. Working on the higher level abstractions is way more fun and intellectually rewarding.
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I know that publication databases are not correct. This time two of my publications have been removed from my entry from Web of Science, one I can see: webofscience.com/wos/woscc/full… . I have no idea why this is the case.
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@AdrianoAguzzi I would cluster the dots by kmeans on the graph, group the clusters and look for patterns. I am not sure a straight line is useful (the variation looks like a lot (but I only know what your y axis is)),
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@AdrianoAguzzi Bill looks like a large language model that digested the entire scientific literature and even understands different genes with the same name.
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@AdrianoAguzzi Gene ontologies are the best way to get a clear description of data. It requires continuous improvements, one gene at a time. Without it there would be even more chaos.
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What's your favourite band logo???
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I can’t believe they left Scaffold out!
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@_MikeMcCartney_ ….of English singing … (missing from the title of the table)
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@AdrianoAguzzi @AndrewHires When you change the x axis without changing the points it looks like gaining weight, too much food could be the answer.
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@AdrianoAguzzi I just have to see a part of the blackboard and guess the rest…
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@AdrianoAguzzi The blackboard seems to be too small for the history… Kang et al Nature 1987 ? (Every Cologne Institute for Genetics student of the time knows).
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@AdrianoAguzzi You see. It is now so easy. You know best what you really need and what the output should look like.
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@AdrianoAguzzi Have you tried to ask for a fee for submitting an article? It would not work for me, but may be worth trying.
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@AdrianoAguzzi Moving to bioinformatics gives you a lot of opportunities. A powerful laptop is all you need. There is so much unexplored data available.
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@AdrianoAguzzi The space is pretty empty. In Germany there are some senior researchers post retirement Helmholtz?
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