Wen-Xing Ding

@jclinicalinvest @KUMedCenter More than 7 years hardworking from talented student Xiaowen and postdoc Xiaoli and Mengwei. Thanks our collaborators Hiromi etc. Megamitochondria accumulation leads to impaired mitophagy and cGAS-Sting activation that promotes liver tumorigenesis.

@wxding1 @KUMedCenter Genetic disruption of mitochondrial dynamics and stasis leads to liver injury and tumorigenesis

In the 1960’s, #megamitochondria in hepatocytes were identified in injured liver tissue. Here, Wen-Xing Ding @wxding1 & team @KUMedCenter find alterations in mitochondrial dynamics and the accumulation of large mitochondria contribute to #liver #tumor development in mice: doi.org/10.1172/JCI194… # MASH The EM image shows liver cells with megamitochondria (arrows) from mice lacking liver-specific dynamin-related protein 1 (Dnm1).

🍺🍔What is MetALD—and why does it matter? US NIH’s Prof. Bin Gaoleads a 🌍 global team of 20+ international expertsto deliver a landmark review on Metabolic dysfunction & Alcohol-associated Liver Disease (MetALD) 🔍 Clear concepts ⚙️ Mechanistic insights ⚠️ Key research & clinical challenges ahead 📖 Open access🔗doi.org/10.1136/egastr… #MetALD #LiverDisease #Hepatology #MASLD #ALD #NIH #OpenAccess @gaobinge @juanpabloarab @l_suthat @wxding1 @GSzaboMD @MehalWajahat @rabataller @FrankTacke @Gut_BMJ @FrontGastro_BMJ @BMJOpen_Gastro @BMJ_Open

✌️ Days Away! Don't miss part ☝️ of our three-part webinar series, Intro to #AI in #BioMedicine, Thursday at Noon EDT. Register for one, two, or all three sessions! bit.ly/4esfEiq

Join us next Thursday at Noon EDT for part ☝️ of our three-part webinar series, Intro to #AI in #BioMedicine. Register today for one, two, or all three sessions! bit.ly/4esfEiq

#CallforPapers @AJPathology seeks your research into Alcohol Induced Organ Damage for our next theme issue. Submission is free and can be done online: editorialmanager.com/ajpa/default2.…

Join AASLD's Hepatotoxicity Special Interest Group (SIG) for this month's seminar Gut-liver Crosstalk Mediated by the Bile Acids-FXR-FGF15/19 Pathway on February 13 at 11:00 AM ET. bit.ly/4hAaC3U

Join us this Thursday Jan 9th 11am EST/8amPST @AASLDtweets #Hepatotoxicity SIG seminar " Using human biomimetic liver microphysiology system and quantitative systems toxicology models to study MASLD and DILI" presented by Drs. Vernetti & Miedel, from @PLRC_PittLiver Register here: aasld.zoom.us/meeting/regist… @livertox @wxding1 @TFFVIIa @electedmaux410 @jacobbogdanovmd @LaylaShojaie @nagachalasani @DeHalegoua @audayan @ChrisKohMD @DrPMonga @DavidKleiner12 @RobertFontanaMD @jonnysexton @rajVuppaLanchi @sidbarritt4 @GinaChoiMD @BurcinEkser

@PLRC_PittLiver @DrPMonga @AASLDtweets Congratulations Dr Michalopoulos! Well deserved! Very lucky to have worked at Pitt Pathology.

Congratulations, Dr. Michalopoulos to the well deserved AASLD Distinguished Achievement Award! We all appreciate your accolades, mentorship and comradery! @DrPMonga @AASLDtweets

You don’t need to know each detail Just know prizes may land in your email Whether he knows it or not David Kleiner’s your bot If you win, he records your new….voicemail Also there are coffee mugs. 😁 @DavidKleiner12 @AASLDtweets See you all at Wait Wait…

Great first day with great science on alcohol associated liver disease: 3rd Johns Hopkins DELTA Center Symposium on Alcohol-associated Hepatitis: Pathogenesis, Treatment and Challenge

@MizLabUT Congratulations Noboru!

水島研究室20周年記念BBQを開催しました！世代を超えて集まった仲間たちと、思い出話や近況報告に花が咲きました。水島先生のもと育った卒業生たちが各々の場で活躍する姿に刺激を受け合い、笑顔溢れる楽しいひと時でした。これからの水島研と皆の更なる成長をお祈りします！#水島研究室 #20周年

Full article: Quality control of mitochondria involves lysosomes in multiple definitive ways tandfonline.com/doi/full/10.10…

Registration, abstract submission, and award applications are open for #Pathobiology2025! Join us in Portland, OR next April for fantastic science 🔬 bit.ly/4ewLvgP

Further information and registration details can be found here: events.jhu.edu/form/jhu-sympo…

a great opportunity to get together for meeting at DC for alcohol related liver disease research: great line up of outstanding speakers, great location, great season and great food…..

@TFFVIIa @audayan @pritchardmt @DrXLongZheng Thanks for coming back. We and students really enjoyed your visit

12 years later, clicked my heels together, and landed back in Kansas. Genuine thanks to @wxding1 for inviting me, and for hosting a “no place like home” seminar. To so many friends and colleagues for a great visit, thank you. @audayan @pritchardmt @DrXLongZheng #RockChalk

#mdpilivers Welcome to read the paper "Targeting #Autophagy for #Acetaminophen-Induced #LiverInjury: An Update". Free full-text: mdpi.com/2673-4389/4/3/…

We are excited to announce that The Hepatotoxicity SIG Seminar Series returns Thursday September 12th 11am ET/8am PT with a talk by Dr. Fernando Besson Title: Long-term Experience of the Latin DILI Networking Focusing on NSAIDS. Registration link: aasld.zoom.us/meeting/regist…

@l_suthat @SekiEki @beckylmcc @CristiLlorente Look forward to the meeting

Join us @beckylmcc at the GRC Meeting on alcohol-induced end organ diseases. Don’t miss out on engaging discussions, networking opportunities, and inspiring talks in a stunning coastal setting!