Youngdo Koo, PhD

New! Online now: Gut substrate trap of D-lactate from microbiota improves blood glucose and fatty liver disease in obese mice dlvr.it/TMB0yf

FGF21 reverses MASH through coordinated actions on the CNS and liver dlvr.it/TLjSnX

New! Online now: FGF21 promotes longevity in diet-induced obesity through metabolic benefits independent of growth suppression dlvr.it/TLNfFX

Pyruvate kinase M2 activation reprograms mitochondria in CD8 T cells, enhancing effector functions and efficacy of anti-PD1 therapy dlvr.it/TL9ZF0

Pyruvate metabolism enzyme DLAT promotes tumorigenesis by suppressing leucine catabolism dlvr.it/TL8Pky

FGF21 analogs reduce liver steatosis and fibrosis in patients with MAFLD/MASH. Our new paper provides insight into the mechanisms for these effects: cell.com/cell-metabolis… @HammDiabetesCtr @OUHealth

New! Online now: Acetylated cellulose suppresses body mass gain through gut commensals consuming host-accessible carbohydrates dlvr.it/TKpZlQ

New! Online now: Foxp3 confers long-term efficacy of chimeric antigen receptor-T cells via metabolic reprogramming dlvr.it/TKZGgL

New! Online now: Fasting-induced ketogenesis sensitizes bacteria to antibiotic treatment dlvr.it/TKVFsK

Starvation induces metabolic hepatocyte reprogramming go.nature.com/42GRRWx

Signalling from adipose tissue to the brain is not just about leptin go.nature.com/3XXwIGb

New! Online now: Pyruvate kinase M2 activation reprograms mitochondria in CD8 T cells, enhancing effector functions and efficacy of anti-PD1 therapy dlvr.it/TK5hqS

New! Online now: O-GlcNAcylation-mediated endothelial metabolic memory contributes to cardiac damage via small extracellular vesicles dlvr.it/TK4lJ4

Identification of a molecular resistor that controls UCP1-independent Ca2+ cycling thermogenesis in adipose tissue - ScienceDirect sciencedirect.com/science/articl…

Hepatic stellate cells regulate liver fatty acid utilization via plasmalemma vesicle-associated protein dlvr.it/TJzF6g

Caloric restriction prevents inheritance of polycystic ovary syndrome through oocyte-mediated DNA methylation reprogramming dlvr.it/TJyJMT

Muscle-derived small extracellular vesicles induce liver fibrosis during overtraining dlvr.it/TJtwbj

Is IDOL an Ideal Target for Treating Atherosclerosis? | Arteriosclerosis, Thrombosis, and Vascular Biology ahajournals.org/doi/full/10.11…

New! Online now: Remote limb ischemic conditioning alleviates steatohepatitis via extracellular vesicle-mediated muscle-liver crosstalk dlvr.it/TJfBzm

New! Online now: Pyruvate metabolism enzyme DLAT promotes tumorigenesis by suppressing leucine catabolism dlvr.it/TJd12Y