Scott Coyle

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Scott Coyle

Scott Coyle

@CellRaiser_

cells and proteins. molecular machines. Assistant Professor: @uwbiochem | Postdoc: @stanford @prakashlab | Ph.D.: @ucsf Wendell Lim @CDI_UCSF

San Francisco, CA Entrou em Ekim 2018
235 Seguindo1.3K Seguidores
Scott Coyle
Scott Coyle@CellRaiser_·
Excited to share a new paper from the super creative and talented @EdenChang_! Eden engineered droplet-forming sequences to act as regulatable glues for stitching microtubules together inside living cells 🧫🧪
Eden@EdenChang_

I'm thrilled to share my first project in @CellRaiser_ 🤩we found that MTs-assembly can be tuned at both MTBD and condensates. This project highlights my past(microtubule), present(SynBio), and future(LLPS): doi.org/10.1016/j.jbc.…

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Krishanu Saha
Krishanu Saha@sahakris·
Thrilled to share our collaborative study led by Brent Aulston and @Musing_Naiad in my lab! 👇This work is a pivotal proof-of-concept in mice showing that in vivo #CRISPR editing in the brain has potential to treat Alzheimer’s disease. 🌟🧠 @NIGMS @somaticediting
Subhojit Roy, MD, PhD@Roy_Lab_Thinks

Gene editing of APP C-terminus rescues neuropathology, ephys, behavior, and transcriptomic changes in #alzheimer knockin mice. Led by Brent Aulston, collaboration with labs of @sahakris @MarkZylka @MarceloWoodUCI Jon Audhya (Madison) #crispr #therapeutics biorxiv.org/content/10.110…

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Hannah Wayment-Steele
Hannah Wayment-Steele@HWaymentSteele·
Some say hybrid comp/expt labs, where dry lab meets wet lab, are "at the beach". Hbt "the shore of Lake Mendota" ? I'm thrilled to join Biochemistry at UW-Madison! Starting 2025, the Wayment-Steele lab will unite AI & experiment to transform how we study biomolecular dynamics.
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Jason R. Cantor
Jason R. Cantor@JasonRCantor·
enjoy the awesome experience, science, and people @kyle_flickinger and @JustWadeAMinute! super proud of & very excited for you both! way to rep metabolism & interdisciplinary work @uwmadisonipib @UWBiochem @Morgridge_Inst cc: @JudithSimcox @RutterLab @gsducker
U of Utah Dept of Biochemistry@UofUBiochem

On Monday (May 20th) starting at 9am in HSEB 1700, we look forward to welcoming 10 talented Graduate Student Rising Stars! Don't Miss it! @uofunuip @AnnaliseBond @Heankel_ @JustWadeAMinute @jaee_saucy @MarissaNT96 @kyle_flickinger @dumebiike @Sam_K_Zepeda @DucHuynh1393 @dacolon

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Anthony Vecchiarelli
Anthony Vecchiarelli@CellfOrganized·
Tenured. Thankful. Look out.
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Scott Coyle
Scott Coyle@CellRaiser_·
Ingenious strategy to repurpose a bacterial E1-like enzyme to emulate ubiquitin-like cascades for ATP-driven protein ligation. Its like a battery pack for powering bioconjugation reactions 🔋!
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Krishanu Saha
Krishanu Saha@sahakris·
At #ASGCT2024, we're showcasing advances in non-viral gene editing, CAR T cell therapies, & high-throughput screening. Explore our work on vision restoration, cancer therapy, and ethical challenges in the field. Join us to learn about the latest progress in #GeneTherapy research
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Megan Nicole McClean
Megan Nicole McClean@McCleanLab·
Happy to share that work led by grad students Zack Harmer and Jaron Thompson, with significant contributions from David Cole, is now out in the journal @ACSSynBio. This work developed out of a productive collaboration with the research groups of Zavala and Venturelli.
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BoWangLab
BoWangLab@PhysPlanaria·
Imaging the entire course of tissue regeneration requires transparent animals, efficient transgenesis & microscopes that can image free-behaving animals. Here we present a toolkit and reveal dynamic cellular processes during regeneration of Macrostomum. biorxiv.org/content/10.110…
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American Society for Cell Biology
American Society for Cell Biology@ASCBiology·
ASCB MEMBER NEWS Judith Kimble & Others Wins the 22nd Annual Wiley Prize in Biomedical Sciences Congrats to ASCB Member Judith Kimble & colleagues who won the 22nd annual Wiley Prize in Biomedical Sciences for their discovery of the stem cell niche. ow.ly/bhrX50Rpfhf
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Vatsan Raman
Vatsan Raman@vatsanraman·
Excited to present PHAGEPACK for quantifying genome-wide which bacterial host factors impact phage infectivity. PHAGEPACK combines CRISPRi with phage packaging. Reveals phage-host interactions, evolution, & host resistance. Great work by @chuchitboonthav! biorxiv.org/content/10.110…
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Elio Challita
Elio Challita@eliochallita·
Incredibly honored to be selected as one of the 2024 @SchmidtFellows! Excited to join the SSF community and collaborate with so many inspiring individuals. Looking forward to this journey ahead!
Schmidt Science Fellows@SchmidtFellows

We’re so excited to announce our 2024 Schmidt Science Fellows.  32 exceptional early career scientists will join our global community to pursue interdisciplinary research and help change how science is done. schmidtsciencefellows.org/news/eric-and-…

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Prof. Nikolai Slavov
Prof. Nikolai Slavov@slavov_n·
The regulatory capacity of dynamic systems is rich & fascinating. They can enable a common regulatory hub to differentially regulate diverse physiological processes. pubs.acs.org/doi/full/10.10…
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Adam Cohen
Adam Cohen@AdamEzraCohen·
We have a new preprint on optical patterning of Nodal signaling in zebrafish embryos: using light to sculpt embryonic development! biorxiv.org/content/10.110… Beautiful work led by @LordLab_Pitt and @h4rrymcnamara
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Nathan Lord@LordLab_Pitt

We’re very excited to share the first preprint from my lab along with @h4rrymcnamara, @BillZJia, @AdamEzraCohen, and Alex Schier. We describe a set of methods for exerting spatial control over Nodal signaling in zebrafish development. biorxiv.org/content/10.110…

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Vatsan Raman
Vatsan Raman@vatsanraman·
We made the cover of @CellSystems! Elementary landscapes for two fitness functions reveal that combining them creates a more rugged landscape. This highlights the demand on a DNA-binding domain to evolve affinity for distinct half-sites @Jackson_Lab tinyurl.com/yc2web9a
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@EdenChang_ @Musing_Naiad @NIGMS @somaticediting @Taylor_Kubota @kyle_flickinger @JustWadeAMinute @uwmadisonipib