Hugo Bayer

New paper alert! 🚨 In this study we explored how interactions between the locus coeruleus (LC), basolateral amygdala (BLA), and the ventromedial prefrontal cortex (vmPFC) affect freezing behavior and extinction learning. 🧵(1/5) pnas.org/doi/10.1073/pn…

Thanks to all the amazing collaborators who made this work possible!

These results reveal a circuit mechanism by which LC–NE biases activity of BLA→vmPFC to generate a heightened fear state. The better understanding of this circuit may help explain stress-related impairment of fear extinction in disorders such as PTSD. 🧵(5/5)

New paper alert! 🚨 In this study we explored how interactions between the locus coeruleus (LC), basolateral amygdala (BLA), and the ventromedial prefrontal cortex (vmPFC) affect freezing behavior and extinction learning. 🧵(1/5) pnas.org/doi/10.1073/pn…

@dudelbem Interessante o dado - na sua opiniao formar menos doutores/ano seria uma boa?

Por ano, o Brasil forma entre 20 e 25 mil doutores há vários anos. Para ter uma ideia, USP+UFRJ+UNESP+UFMG+UFF+UFRGS somam ~22 mil docentes. Ou seja, absorver todos exigiria criar, POR ANO, vagas equivalentes ao total das 6 maiores universidades do país. É preciso saber disso.

@MicTott Thanks man!

Locus Coeruleus-Amygdala Circuit Disrupts Prefrontal Control to Impair Fear Extinction - congrats @HugoBayer1! biorxiv.org/content/10.110…

Congratulations to the newly minted Dr. Hugo Bayer (@HugoBayer1 ) !! Great work and super cool story ! 🍾👏🥳🎉

Most neurotransmitter systems and intracellular elements are most important during and immediately after memory recall, while others are more involved at later time points, especially those supporting long-term persistence mechanisms triggered by memory recall.

We looked at evidence from all sorts of fear memory reconsolidation studies and tried to determine what is known about the temporal dynamics of different systems that contribute to memory reconsolidation and persistence after recall.

How are long-term memories stored in the amygdala? How are old memories integrated with new memories over time? We discuss this and more in a new review led by @JianfengLiu6 with @HugoBayer1 and @StephenMaren. biologicalpsychiatryjournal.com/article/S0006-…

@okaysteve Super cool stuff!

Today, our 🐭lab celebrates 18 years — congratulations and a big thank you to members and alumni! @CristinaStern, @HugoBayer1, @Isabeus_,@Lgazarini

@OdedRechavi And then the experiment turns out like a Lynch movie

Every lab meeting

@cardosorodrigo2 @NIH @UNeurobiology @not_kristie O brabo tem nome

Very happy to visit @NIH, meet amazing people, and share the science I'm doing at @UNeurobiology as a 2024 Outstanding Scholar in Neuroscience Award Program #OSNAP recipient. Thanks for this honor, and to my PI @not_kristie and lab mates for supporting me on this journey!

📣 New Cai Lab paper in @CellReports! We show that a stressful experience can produce different types of memories! We also find that the basolateral amygdala (BLA) & ventral hippocampus (vHC) differentially contribute to these memories 🧠 cell.com/cell-reports/f… More ⬇️ (1/6)

Connectome: anatomy Network: a bunch of connected neurons circuit: a bunch of connected neurons PCA: beginner level magic Manifold: advanced magic neural dynamics: neural activity dynamical system: anything that changes attractor: stable state in neural activity

Did you catch this recent @npp_journal Research Highlight from @doc_becca & @ElizaMackenzieG regarding a cover cortical ensemble for learned fear suppression?😱 Check out the original article from @StephenMaren & @HugoBayer1 : nature.com/articles/s4138… nature.com/articles/s4138…

🌟Review Alert! Excited to share our latest article, where we explore the effects of serotonergic #psychedelics and related substances (e.g., MDMA) on extinguishing and reconsolidating aversive memories, expressing fear/anxiety, and locomotion in rodents. authors.elsevier.com/a/1jq5GY3M3i2PZ