The Matic Lab

Check out our latest #research on ADP-ribosylation signaling, published in@NatureComms and led by our former PhD student @ELongarini! 🥳  nature.com/articles/s4146…

We are happy to share that our latest study on ADP-ribosyl-linked serine ubiquitylation in the context of PARP1 signaling and the DNA damage response is out in Nature Chemical Biology! 🥂🎉☺️ nature.com/articles/s4158…

These new antibody development efforts align with our vision that the fundamental discovery of Serine ADP-ribosylation can be converted into a technology that transforms the study of ADP-ribosylation and related PTMs.

This preprint is part of a larger manuscript on additional antibodies and their applications to biological questions. The goal of this preprint is to share these poly-ADPr with the community without delay, as we believe they will benefit many laboratories.

We’ve uploaded a bioRxiv preprint on new antibodies specific for poly-ADP-ribosylation (PARylation). These modular tools were developed and validated through novel applications of our Serine ADP-ribosylation-based technology. biorxiv.org/content/10.110…

Welcome to the newly elected EMBO Members Oliver Hobert @Columbia_Bio, Valérie Borde @lab_borde, Lumír Krejci @MasarykUni, Ivan Matić @Lab_Matic, Ewelina Knapska @e_knapska, Steven West @XRNchew, Ita Gruić-Sovulj, Martin Howard @JohnInnesCentre and Paola Scaffidi! #EMBOat60

We're ready for @EMBO Fellows Meeting!✨ #EMBOat60

Great event for RNA aficionados. Samantha will present her PhD project on a lncRNA in podocyte biology.

Last week we had the pleasure of hosting Professor Lee Kraus from UT Southwestern in Texas. After an insightful talk @MPIAGE and a fruitful round table discussions about science, industry and much in between, we continued our evening in a traditional German restaurant. 🍻

Our new paper describing how tyrosine-linked ADP-ribosylation signalling is reversed. Big thanks to our collaborators @JgmRack, @LeidenADPr and @Lab_Matic. jbc.org/article/S0021-…

New work in collaboration with @IvanAhelLab , @JgmRack and @Lab_Matic ! Tyr-ADPr solved! Despite its acid sensitivity 🫠

SEMINAR: Discovery and development of Serine ADP-ribosylation, Dr Ivan Matić; Max Planck Institute for Biology of Ageing Tuesday 17th September, 1.30-2.30pm Details: babraham.ac.uk/seminars/2024/…

Our new paper demonstrating reversible ubiquitylation of DNA and RNA: embopress.org/doi/full/10.10…

Last week two of our lab members attended the #NADSRC in sunny Lisbon ☀️🌊 Our Serine-ADPr technnology was showcased in a talk by our postdoc Helen, and she and our PhD student Mihaela presented it during two successful poster sessions! ☺️

🔬Biochemist Dr. Ivan Matić from the @MPIAGE for Biology of Ageing has spoken at the @LeibnizFLI yesterday about the latest discoveries and developments of his research group on protein modification ADP-ribosylation.💡 @Lab_Matic #ScienceResearch #aging youtu.be/JYP2PPrhEH4

As mentioned some time ago, there is an opening for a mass spec specialist (post-doc) working between our lab and the metabolomics facility @CECAD_ to support the Bioanalytical Platform of @CRC1218, sfb1218.uni-koeln.de Send your applications here: jobs-uk-koeln.de/index.php?ac=j…

@AkisPapantonis Thank you!

@Lab_Matic Well deserved, Ivan!

Where is Ivan Matić? Try to find his photo among the new EMBO 2024 members! Exciting times 🥳🥳🥳🥳

👏Double Congratulations!👏 ​​​​​​Aleksandra Trifunovic and Ivan Matić have been elected new @EMBO members for their pioneering science in mitochondrial biology and protein modifications! 🎉 @AleXTrifunovic @Lab_Matic @UniCologne @MPIAGE #EMBOmembers cecad.uni-koeln.de/outreach/news/…

@DemetriadesLab Thank you, Costas!

@Lab_Matic Huge congrats, Ivan! Fantastic news!