Signild Åsberg

38 posts

Signild Åsberg

Signild Åsberg

@SignildAsberg

Stroke physician and researcher. Member of the steering committee, the Swedish Stroke Register

Uppsala, Sverige Присоединился Ağustos 2014
63 Подписки74 Подписчики
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Urs Martin Fischer
Urs Martin Fischer@FishingNeurons·
When to start anticoagulation after an ischaemic stroke in people with atrial fibrillation? Attached please find a comment in the NEJM Journal Watch on our CATALYST meta-analysis, published in The LANCET. @BoNorrving @SignildAsberg
NEJM Clinician@NEJMClinician

In patients with atrial fibrillation, starting anticoagulation within 4 days after acute ischemic #stroke rather than later leads to fewer early recurrent strokes with no significant intracranial hemorrhage signal, a meta-analysis suggests. jwat.ch/4l6sdS8 #NeuroTwitter

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Bo Norrving
Bo Norrving@BoNorrving·
@TheLancet Very happy to see this in print, the result of 8 years of collaboration between the RCT:s on this topic. The final result of the individual patient data systematic analysis showed that the total was larger than the parts; a demonstration of the power of evidence based principles
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Urs Martin Fischer
Urs Martin Fischer@FishingNeurons·
Many thanks to all the CATALYST collaborators, who helped us to solve this old dilemma in acute stroke management: there is no reason to delay anticoagulants in ischemic stoke patients with atrial fibrillation! @inselgruppe @StrokeBern @unibern
Insel Gruppe@inselgruppe

Internationale Studie zeigt: Frühzeitige Blutverdünnung nach Schlaganfall ist sicher & wirksam. Patient:innen mit Vorhofflimmern profitieren deutlich – 30 % weniger Folge-Schlaganfälle. Mehr: neurologie.insel.ch/de/aktuelles/d… #InselGruppe #Schlaganfall #Neurologie @FishingNeurons

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European Stroke Org
European Stroke Org@ESOstroke·
🧠 The European Stroke Science Workshop, ESSW, brings together leading clinician-scientists and researchers in a highly interactive setting. Applications for mid-career researchers who are ESO members are open until 25 April 2025 – 👉 ow.ly/zFW150Vsn2g #stroke
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OPTIMAS
OPTIMAS@OPTIMAS_UCL·
Don't miss the presentation of the OPTIMAS and CATALYST results this week at #WSC2024, which will be featured in Day 2's plenary session!
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OPTIMAS
OPTIMAS@OPTIMAS_UCL·
Congratulations to @BoNorrving who received the @ESOstroke Honorary Award this year for his incredible work in stroke care, research and advocacy! #ESOC2024
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OPTIMAS
OPTIMAS@OPTIMAS_UCL·
@SignildAsberg earlier gave us a comprehensive overview of registry-based RCTs! #ESOC2024
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OPTIMAS
OPTIMAS@OPTIMAS_UCL·
The new 2023 National Clinical Guideline (strokeguideline.org) has a recommendation for patients with moderate/severe ischaemic stroke: "wherever possible these patients should be offered participation in a trial of the timing of initiation of anticoagulation after stroke"
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Signild Åsberg
Signild Åsberg@SignildAsberg·
@DavidSeiffge @BoNorrving Thank you David, TIMING is the first RRCT in the stroke field demonstrating NOAC to be safe also in the acute phase of ischemic stroke w AF. Still, further evidence is needed and I can’t wait to see result from our collaboration with @OPTIMAS, @ELAN and START (@warach_steven)
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World Stroke Academy
World Stroke Academy@WorldStrokeEd·
#TIMING Early vs delayed #NOAC start after acute ischemic stroke 🧠💊🩸 @BoNorrving 👏 Presented at #ESOC2021, now you can read the full article here 👇🏻 ahajournals.org/doi/abs/10.116…
World Stroke Academy@WorldStrokeEd

#WeekendLecture #ESOC2021 #TIMING What is the optimal time-point to start #NOAC after acute ischemic #stroke? ✍️Registry based, randomized study from 🇸🇪 888pts Early start (<4d) vs delayed (5-10d) 1ry oc: composite👉IS/sICH/all cause mortality ☝️Early start was non inferior

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Signild Åsberg
Signild Åsberg@SignildAsberg·
@syaddana_neuro Subgroups findings in Fig 6 should be interpreted cautiously, but the actual proportion of pts with NIHSS≥15 was 9% (early) and 8% (delayed). NIHSS was 4 (median) and 6 (mean) in both groups.
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Signild Åsberg
Signild Åsberg@SignildAsberg·
@MicieliA_MD @syaddana_neuro In the nation-wide pragmatic TIMING study, there were no inclusion/exclusion criteria based on NIHSS. Still, NIHSS was 4 (median) in both the early and the delayed group, as compared to 3 in the general Swedish stroke population with AF & NOAC.
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