Anders J. Skanderup

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Anders J. Skanderup

Anders J. Skanderup

@anders_js

Computational cancer genomics

Genome Institute of Singapore Присоединился Nisan 2010
48 Подписки224 Подписчики
Anders J. Skanderup ретвитнул
Roel Verhaak
Roel Verhaak@roelverhaak·
Really clever approach to help understand the impact of broad copy number changes: Cancer aneuploidies are shaped primarily by effects on tumour fitness nature.com/articles/s4158…
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Anders J. Skanderup ретвитнул
Chris Sander aka cscbio
Chris Sander aka cscbio@sandercbio·
Go cBioPortal ! Lots of new features for easy analytic access to cancer genomics, proteomics and more. Make your own discoveries on community-provided cancer data and analysis tools.
cBioPortal@cbioportal

Come learn about cBioPortal at #AACR2023: Talks on Saturday by @NikolausSchultz at 8:30 AM in Room W224 (#NCIITCR session) as well as by Tali Mazor in Room W311 at 8:45 AM (@AACR Project GENIE session), a poster on Tuesday morning, and a booth in the exhibitor space (#1943).

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Anders J. Skanderup ретвитнул
Shyam Prabhakar Lab
Shyam Prabhakar Lab@shyam_lab·
#Fluoxetine (#Prozac) changes so many genes in so many brain regions. Mechanism(s) of action are dizzyingly complex, but some promising themes emerge👇. Long-term collab with @meaneylab et al. Large integrative omics study heroically led by @braincrank_nr. @astar_gis #depression
Nirmala Rayan@braincrank_nr

Ever wondered how the 'happy pill' Prozac impacts the brain? We did too! Delighted to share our study on the effects of fluoxetine (Prozac) on 27 different rodent brain areas. Paper is out in Molecular Psychiatry & available for free reading. nature.com/articles/s4138… A thread 👇🏾

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Anders J. Skanderup ретвитнул
A*STAR Genome Institute of Singapore (A*STAR GIS)
A*STAR Genome Institute of Singapore (A*STAR GIS)@astar_gis·
1 of the deadliest cancers with diverse etiological factors worldwide. We found unprecedented genomic diff. segregating distinctively across ethnicities & stressed the importance of differential disease biology & management in HCC across ethnicities. thno.org/v12p4703.htm
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Anders J. Skanderup ретвитнул
Nature Genetics
Nature Genetics@NatureGenet·
‼️ OUT TODAY @NatureGenet 📰 Single-cell and bulk transcriptome sequencing identifies two epithelial tumor cell states and refines the consensus molecular classification of colorectal cancer 🧑🏿‍🤝‍🧑🏼 @iaintan_mdphd @shyam_lab @astar_gis and colleagues 👇🏿 go.nature.com/3bI7ZA8
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Anders J. Skanderup
Anders J. Skanderup@anders_js·
Excited to share our new study and resource on tumor metabolism with @rohatgineha @astar_gis. Using tumor transcriptome deconvolution, we identify metabolic differences of cancer and stromal cells inside tumors. Some expected and unexpected findings ... doi.org/10.1016/j.celr…
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Anders J. Skanderup ретвитнул
Roel Verhaak
Roel Verhaak@roelverhaak·
Those signatures that were reported in that amazing 18k WGS analysis paper in Science yesterday? They can all be browsed on the amazing Signal resource portal! signal.mutationalsignatures.com. 😎
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Anders J. Skanderup ретвитнул
Roel Verhaak
Roel Verhaak@roelverhaak·
Effective drug combinations in breast, colon and pancreatic cancer cells. 2025 drug combinations vs 125 cancer cell lines 😮nature.com/articles/s4158…
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Anders J. Skanderup ретвитнул
Roel Verhaak
Roel Verhaak@roelverhaak·
Wonderful portal that enables exploration of the phenomenal Hartwig metastatic cancer WGS/RNAseq cohort.
Edwin Cuppen@ecuppen

Pleased to announce our novel catalog interface of the Hartwig database with whole genome sequenced tumor genomes: catalog.hartwigmedicalfoundation.nl. Currently more than 5,000 patients, including treatment and response data. Plus RNA-seq data for more than half of the patients.

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Anders J. Skanderup ретвитнул
Chris Sander aka cscbio
Chris Sander aka cscbio@sandercbio·
Collaboration with Sjoerd van Hagen, Sander Rodenburg and Elena Garcia Lara @TheHyveNL and Augustin Luna @canninl - more to come as CPTAC enters its next phase. Go proteomics in cancer profiling!
cBioPortal@cbioportal

We added several new studies from @NCItreatment's Office of Cancer Clinical Proteomics Research CPTAC project, with protein and phospho-protein levels from 892 samples across 7 cancer types. Thanks to @TheHyveNL for the curation help.

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Anders J. Skanderup ретвитнул
Daniel Tan
Daniel Tan@danieltanmd·
Excited that our paper is online! Highlights how pervasive lineage transition occurs at a transcriptomic level in T790M neg resistance, suggesting the potential for tissue-based integrative analysis to forecast resistance trajectories in EGFR M+ NSCLC. clincancerres.aacrjournals.org/content/early/…
Central Region, Singapore 🇸🇬 English
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