

Clockwork
422 posts

@this_clockwork
A youtube channel exploring biochemistry. https://t.co/8DE8sGlrVh





Another YouTube Channel Idea: "E. coli Design." A whole series where you explain how to design DNA to change the behavior or appearance of E. coli cells. All you'd need is some equipment to transform cells, a microscope and camera, and some basic molecular biology equipment. Some ideas for modules: 1. The basics of a transcription unit; inserting GFP into cells and watching them glow. 2. Using a base editor to change GFP into another color? 3. Engineering E. coli to spin around in circles. 4. Engineering E. coli to swim faster, or to grow larger, or to partition their DNA unevenly, etc. ... and then end the series with the repressilator and blinking bacteria or something. You could inspire tens of thousands of future bioengineers and completely demystify this space. Plus it's so cool to directly show how DNA sequences can lead to physical, observable changes in the cell.






I'm very happy to announce that I have retired! I'm equally happy that @janetiwasa has agreed to continue the Molecule of the Month @buildmodels. Read about this at cdn.rcsb.org/rcsb-pdb/gener…


Announced: The PDB Molecule of the Month for December is the flagellar motor! An informative article paired with a beautiful artwork by Dr. David Goodsell. pdb101.rcsb.org/motm/300 @buildmodels @dsgoodsell #Science #Discovery #PDB This is my favorite Molecule of the Month!






Hi! My new book, Everything Is Tuberculosis, comes out March 18th. I'm signing 100,000 copies of it. You can preorder your signed copy today at everythingistb.com or wherever books are sold.




Amazing talk from @JohannJRoske at the #LMB lab talks! Thanks to @this_clockwork for bringing the replisome to life 🧬🧬🧬