Andre Marette

🎉 Exciting news! Led by @mackgutierrezz, our latest on the gut mycobiome and its role in metabolic health is now published in @NatureComms ! 🧫🍄 Explore how fungal colonization influences obesity and metabolic inflammation in mice. shorturl.at/Sstq0 🧵

HUGE news! 🎉 Our lab just received a @CIHR_IRSC grant to study the impact of high fructose on the microbiome & gut-liver axis! A big thank you to @SchertzerLab @AndreMarette @justnotpretty & reviewers. Exciting discoveries are on the horizon! @facmedUL @IUCPQ @INAF_Qc

On #WorldDiabetesDay2024 congratulations to Professor Erin Mulvihill @HeartInstitute @OttawaU @uOttawaBMI @CIHR_IRSC this years receipient of the early career investigator award from @DiabetesCanada Felicitations! #diabetes

🤯Wow! Another outstanding study from @AnaDomingosLab showing that peripheral vs central NPY has opposite effect on body weight independently of food intake!! nature.com/articles/s4158…

This is our first major paper of the lab showing early life modulation of T1D development, linked to maternal IgA deficiency. Super proud of the work twitterless Erinnand Luisa have done!

Maladie hépatique: un extrait du fruit camu-camu pour dégraisser le foie @AndreMarette @facmedUL @IUCPQ ow.ly/ztH650T35Js

@StephenORahilly Really sorry to hear this. A huge lost to the metabolic field.

Very sorry to hear this terrible news

@kazaklab @Parklabmcgillu @thomas_duchaine @McGillGCI @mcgillu Congrats Lawrence!

Tenured. Thanks to all Kazak lab members - past and present - for their hard work, curiosity, and trust in the scientific process. Thanks to @Parklabmcgillu and @thomas_duchaine for their leadership. And thanks to the anonymous letter writers. @McGillGCI @mcgillu

I am delighted to share that I have been promoted to Associate Professor as of today! Thanks to all my lab members, the students I have had the privilege of supervising and teaching since 2020, and all my wonderful colleagues and mentors. Looks like we will keep sciencing!! 🤩

Forcing such trials to conform to a rigid registration process defining primary and secondary outcomes designed for de facto clinical trials is undermining human physiological research, and this requirement should be abolished.

Contemporary experimental physiological trials are often focused on revealing mechanisms to determine how a particular intervention, such as exercise or a diet, affects a particular physiological outcome and are thus hypothesis generating rather than hypothesis driven.

We contend the ICMJE’s guidelines are unsuited for experimental physiological studies, as the outcomes of physiological experiments demonstrate the remarkable adaptability of the human body and are not consistent with clinical trials in patients, where the focus is on a disease.

This implies that even basic mechanistic studies on exercise or diet, as well as physiological studies on healthy individuals undergoing exercise training, are now being labeled as "clinical trials" due to their potential health-related physiological outcomes.

ICMJE defines clinical trials as "any research project that prospectively assigns people or a group of people to an intervention, with or without concurrent comparison or control groups, to study the relationship between a health-related intervention and a health outcome".

Exploratory physiological experiments are not clinical trials. Letter to the Editor at Cell Metabolism authors.elsevier.com/a/1i%7EWj5WXUl…

We urge journals to adopt a more flexible stand, abandon the ICMJE guidelines and perhaps use a questionnaire for authors to fill out when submitting a paper that then determines if a study is a clinical trial or an experimental physiological study.

@Nat_Mich @universitelaval @IUCPQ Congrats. Well deserved indeed!👍

Honoured to have been awarded a Tier 2 Canada Research Chair #CRC in Metabolism and Sleep Neurobiology 🧠 @universitelaval @IUCPQ

⭐️In Memoriam: Denis Richard 1953–2023⭐️ Thank you @EndoKarger for allowing us to pay tribute to a great Québécois who had a profound impact on science and society @IUCPQ @universitelaval karger.com/nen/article/do…