Biology of Sex Differences

New article: Authors write in their conclusion that "this work suggests the effects of sex chromosome complement on pregnancy outcomes may differ by placental cell type." Read more: link.springer.com/article/10.118…

New article: Authors write that "this study employed integrated transcriptomic and metabolomic analyses to decipher sex-divergent neuroendocrine strategies in Cherax quadricarinatus under cold stress." link.springer.com/article/10.118…

Men and women show distinct patterns in type 2 diabetes, from insulin resistance to hormone regulation. These differences affect diagnosis and treatment, highlighting the promise of personalized care. Learn more this #DefeatDiabetesMonth: link.springer.com/article/10.118…

New article: "This study investigated the role of SRD5A2 haplotypes in DSD, focusing on their corresponding phenotypes, structural changes and impacts on enzyme activity" authors write. Read more today: link.springer.com/article/10.118…

New article: In their conclusion, authors write that "Female and male mice exposed to social stress exhibit distinct behavioral adaptations, but similarly, separate into resilient and susceptible subpopulations." link.springer.com/article/10.118…

New article: In this article, authors write that "this review critically re-interrogates the longstanding notion of female sex development as an outcome of mere androgen deprivation." Read on: link.springer.com/article/10.118…

New article: "The specific sex related changes in obesity and their associated with crystallized intelligence still remained unclear," authors state. Read their research to learn more: link.springer.com/article/10.118…

New article: Authors' findings "indicate that, as individuals age, the rate of hormone decline varies, and its effect on aging differs accordingly. In females, the decrease in estrogen levels accelerates aging." Read more about #HRT:link.springer.com/article/10.118…

This week is #WorldAutismAcceptanceWeek! #SexDifferences in gene expression across various brain regions affect thousands of genes, including Autism predispositions. Read more about how gene expression may contribute to these differences: link.springer.com/article/10.118…

New article: "Advancing our understanding of these biological differences and their underlying mechanisms is essential to move beyond one-size-fits-all nutritional recommendations and disease management strategies," authors write. Read more: link.springer.com/article/10.118…

New article: "This study aimed to investigate the association between parental age at reproduction and the timing of pubertal development events in their sons and daughters," authors write. Read more: link.springer.com/article/10.118…

New article: Authors write that "findings from this prospective cohort study suggest that father absence, particularly in the first year of life, is associated with signs of earlier pubertal timing in both girls and boys." link.springer.com/article/10.118…

New article: Authors write that "sex-related tendencies influence strategy use during haptic object memory." Read more: link.springer.com/article/10.118…

New article: Authors here conclude that "findings support a developmental model in which collagen-integrin-mediated extracellular matrix remodeling at a critical post-metamorphic stage, well before sexual maturation." Read the results for more:link.springer.com/article/10.118…

New article: "Our findings provide a cell-resolution, sex-specific understanding of Estradiol’s (E2) profound impact on gonadal adipose tissue remodeling to guide sex-specific therapeutic interventions in obesity," authors write. Read more: link.springer.com/article/10.118…

New article: This work is led by the understand that "the impact of sex on cognition is less understood and previous research has reported inconsistent findings." Authors study this gap, read more: link.springer.com/article/10.118…

New article: Authors write that "the aim of this study was to investigate sex-related differences in the response to oxidized low-density lipoproteins-induced damage in human umbilical vein endothelial cells isolated from male and female newborns." Read: link.springer.com/article/10.118…

This #SleepAwarenessMonth, research from 2025 shows that hypertensive disorders during pregnancy are linked to poorer sleep and higher cardiovascular risk later in life. Studies like this highlight why #Research is essential to support more informed care: link.springer.com/article/10.118…

New article: "This nationwide study using real-world data was performed to evaluate sex-based differences in diagnosis, treatment and survival outcomes in rectal cancer," authors write. Read more: link.springer.com/article/10.118…

New article: "Sex differences profoundly shape immune responses, with sex hormones driving distinct patterns of susceptibility to infectious diseases and inflammatory conditions" authors write. Read the article further: link.springer.com/article/10.118…