CREST-2 Stroke Study

In high-grade asymptomatic carotid stenosis, addition of stenting to medical therapy led to a lower risk of stroke over a 4-year period. Endarterectomy did not lead to a significant benefit. Full results of the CREST-2 trials and Research Summary: nej.md/3LK9kst

Presented at #ISC26, the CREST-2 trial results showed neither the addition of CAS nor CEA to IMM demonstrated cognitive benefit compared to IMM alone, including in patients with worse baseline cognition. Here is @tmadsenem’s take on the results.

CREST-2 results presented at #ISC26

It's a New Year and SVIN has a New, Exciting Grand Rounds Lecture lined up for you! 🌟 CREST-2 Trial: Rethinking Stroke Prevention in Asymptomatic Carotid Stenosis 📅 January 27, 2026 – 12:00 PM CT 🎤 Presenter, Principal Investigator CREST 2 : James F. Meschia, M.D. Register here: zurl.co/YUEJu #SVIN #GrandRounds #CREST2Trial

AAN members, join Drs. James F. Meschia and Brajesh K. Lal on the AAN Section Spotlight webinar (@AANmember) this Wednesday from 5-6PM Eastern! 🎙️ Click on the link to login to your AAN account and register for the webinar: learning.aan.com/webinars/88655

Join Drs. Brajesh K. Lal and Thomas G. Brott on the Frank J. Veith International Society's webinar (@FJVIS1) this Wednesday from 12-1:30PM Eastern! 🎙️ Click on the link to register: us06web.zoom.us/webinar/regist…

James Meschia, MD is the recipient of the 2025 Innovation Award! This award recognizes groundbreaking vision and advancements shaping the future of neurovascular care. Congratulations, Dr. Meschia! Learn more at zurl.co/koC6e #SVIN #SVIN25 #SVINAnnualMeeting #SVINAwards #InnovationAward

CREST 2 RESULTS PRESENTED AT THE 52nd Annual VEITHsymposium BY DR. THOMAS BROTT - Listen to what Dr. Brott and our faculty experts have to say: Favoring stenting …. youtu.be/PPwK-s8cCV4

🚨Post Session Interview with Dr. Meschia discussing the Primary results of the CREST-2 trial presented during our Late Breaking abstracts yesterday! #SVIN25

Presented at #SVIN25: CREST-2: In high-grade asymptomatic carotid stenosis, addition of stenting to medical therapy led to a lower risk of stroke over a 4-year period. Endarterectomy did not lead to a significant benefit. Full results: nej.md/3LK9kst Editorial: Managing Asymptomatic Carotid Stenosis nej.md/482XjG1 @svinsociety

Congratulations to Diana C. De Los Santos at Kaiser Permanente Los Angeles Medical Center (@KPLACounty) for being CREST-2's June Coordinator of the Month! 🏆📷 #CarotidStenosis #Stroke #Research

Congratulations to Dr. Navdeep Sangha at Kaiser Permanente Los Angeles Medical Center (@KPLACounty) for being CREST-2's June Investigator of the Month! 🏆📷 #CarotidStenosis #Stroke #Research

Congratulations to Johnetta Comello at Baptist Health Lexington (@BHLexington) for being CREST-2's May Coordinator of the Month! 🏆📷 #CarotidStenosis #Stroke #Research

Congratulations to Dr. Michael Jones at Baptist Health Lexington (@BHLexington) for being CREST-2's May Investigator of the Month! 🏆📷 #CarotidStenosis #Stroke #Research

Congratulations to Caitlan LeMatty at the Medical University of South Carolina (@MUSChealth) for being CREST-2's April Coordinator of the Month! 🏆📷 #CarotidStenosis #Stroke #Research

Congratulations to Dr. Christine Holmstedt at the Medical University of South Carolina (@MUSChealth) for being CREST-2's April Investigator of the Month! 🏆📷 #CarotidStenosis #Stroke #Research

Congratulations to Genoveva (Geni) Maclean at Vancouver General Hospital (@VCHhealthcare) for being CREST-2's March Coordinator of the Month! 🏆📷 #CarotidStenosis #Stroke #Research

Congratulations to Dr. Philip Teal at Vancouver General Hospital (@VCHhealthcare) for being CREST-2's March Investigator of the Month! 🏆📷 #CarotidStenosis #Stroke #Research

Congratulations to Suzy Lavoie for being CREST-2's December Coordinator of the Month! 🏆📸 #CarotidStenosis #Stroke #Research

Congratulations to Dr. Ariane Mackey for being CREST-2's December Investigator of the Month! 🏆📸 #CarotidStenosis #Stroke #Research