John Bennett

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John Bennett

John Bennett

@ChemBio_John

Colgate 2019 Stanford Chem 👨‍🔬🏳️‍🌈 Bogyo Lab He/him

เข้าร่วม Şubat 2020
123 กำลังติดตาม118 ผู้ติดตาม
John Bennett รีทวีตแล้ว
Goh Zhang-He (he/him) (goh-zhanghe.bsky.social)
Goh Zhang-He (he/him) (goh-zhanghe.bsky.social)@goh_zhanghe·
Congratulations on getting this published! I recall it was a pleasure to highlight this work (at @preLights) when it was still a preprint
John Bennett@ChemBio_John

I'm excited to share our latest collaboration with @fidocklab using mixed alkyl/aryl phosphonates to identify possible drug targets in Plasmodium. Our work offers a possible method for deciphering important drug targets, mechanism of action, and mechanisms of resistance.

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John Bennett
John Bennett@ChemBio_John·
I'm excited to share our latest collaboration with @fidocklab using mixed alkyl/aryl phosphonates to identify possible drug targets in Plasmodium. Our work offers a possible method for deciphering important drug targets, mechanism of action, and mechanisms of resistance.
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John Bennett รีทวีตแล้ว
Matthew Bogyo
Matthew Bogyo@mbogyo·
Happy for these two guys who just graduated last week. They started in the lab 2 days apart and finished 1 day apart. Congrats to @FrancoFaucher and @ChemBio_John. On to many more great things as PhDs.
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John Bennett
John Bennett@ChemBio_John·
This work once again shows the value of targeting serine hydrolases within the parasite with covalent molecules that prevent the rapid evolution of resistance. These types of strategies will be invaluable in the identification of novel mechanisms of action.
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John Bennett
John Bennett@ChemBio_John·
Check out our latest work on Plasmodium with @fidocklab where we explored a novel set of mixed alkyl/aryl phsophonates as tool compounds to identify and probe essential lipid metabolizing serine hydrolases and pathways within the parasite.
Matthew Bogyo@mbogyo

Our latest collaboration with @fidocklab is out. PhD student @ChemBio_John found mixed aryl/alkyl phosphonates that target essential serine hydrolases in Plasmodium falciparum. They kill parasites with low overall induced resistance. biorxiv.org/content/10.110…

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Matthew Bogyo
Matthew Bogyo@mbogyo·
Our latest collaboration with @fidocklab is out. PhD student @ChemBio_John found mixed aryl/alkyl phosphonates that target essential serine hydrolases in Plasmodium falciparum. They kill parasites with low overall induced resistance. biorxiv.org/content/10.110…
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Long Lab
Long Lab@longlabstanford·
Congratulations @AmandaWigg_, thesis work now in press @NatureComms. Inspired by the structure of the hypothalamic hormone TRH (pyroglu-his-pro-amide), Amanda shows “capping” defines a chemical motif present in many previously unknown bioactive peptides nature.com/articles/s4146…
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John Bennett รีทวีตแล้ว
Mekedlawit Setegne
Mekedlawit Setegne@MekedlawitTS·
HAYYYYY, joining the role call as a FIFTH year @StanfordUChem characterizing cholesterol protein interactome in bacterium that makes its own cholesterol 🤯🧫 A girl that wears many hats & interested in using chemical tools to probe molecular biology! #BlackInChemRollCall
Mekedlawit Setegne tweet mediaMekedlawit Setegne tweet mediaMekedlawit Setegne tweet media
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John Bennett
John Bennett@ChemBio_John·
Check out our latest work on how we have used covalent macrocyclic inhibitors of the malaria proteasome to combat the growth of resistance. Big shout-out to @fidocklab @RyanKMuir and everyone else who was a part of this story!
Matthew Bogyo@mbogyo

It's all about covalent inhibitors! See how covalent macrocycles that target the malaria proteasome can prevent resistance. Great work from the Bogyo lab @ChemBio_John in collaboration with @fidocklab. biorxiv.org/content/10.110…

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Laura Keller
Laura Keller@kellerlauraj·
So excited to finally be sharing this story!! Thank you to the many collaborators (including @taylorhnguyen in KC Huang's lab, the teams of @ajodonoghue, @MJNiphakis and Ami Bhatt, and my mentor @MLakeme) for helping me and @mbogyo bring this story to life!
Matthew Bogyo@mbogyo

Our first paper on our efforts mapping serine hydrolases in gut commensal bacteria is out. We identified a homolog of the human DPP4 protease in B. theta that is important for community fitness. biorxiv.org/content/10.110…

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John Bennett รีทวีตแล้ว
Matthew Bogyo
Matthew Bogyo@mbogyo·
Our first paper on our efforts mapping serine hydrolases in gut commensal bacteria is out. We identified a homolog of the human DPP4 protease in B. theta that is important for community fitness. biorxiv.org/content/10.110…
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John Bennett รีทวีตแล้ว
Anthony Chianese
Anthony Chianese@ARChianese·
Check out our latest work on ChemRxiv, where make our first entry into the catalytic hydrogenation of epoxides! This work was done by @ColgateChem students Fallyn Kirlin, Olivia Borden, @mchead12, and Sophie Kelly. doi.org/10.26434/chemr…
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Scott Lovell
Scott Lovell@scottlovell34·
I'm searching for a PhD student to start in my brand new lab @UniofBath in Oct 2022. The project will use phage display for covalent ligand discovery. Retweets are much appreciated. findaphd.com/phds/projectde…
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ค้นพบ

@goh_zhanghe @mbogyo @fidocklab @CellChemBiol @preLights @FrancoFaucher @AmandaWigg_ @NatureComms