Evolution, Systems & Genomics Domain UoM

The Evolution, Systems & Genomics (ESG) domain in FBMH: The Domain is committed to furthering our understanding of fundamental genomic & genetic change and how change affects molecules, individuals, populations &species. Domain director: Prof Simon Lovell research.manchester.ac.uk/portal/simon.l…

Busy week this - welcoming our wonderful colleagues from Manipal in India to our inaugural rare diseases symposium @MFT_Genomics @MFT_SMH @EvolSysGen @OfficialUoM

Gareth Evans from @MFT_Genomics @MFT_SMH @EvolSysGen @OfficialUoM highlighting the importance of genetic tests to optimise breast cancer screening

Our health depends on the health of our planet. By coming together we can better understand, communicate and solve problems that make our world a healthier place to live 👉 wellc.me/2Glhe65 #WorldEnvironmentDay

A selection of publications out of the May Newsletter from Evolution, Systems & Genomics researchers, with commentary from Domain Director Simon Lovell (@lovelllab)

Tapinos et al. The utility of data transformation for alignment, de novo assembly and classification of short read virus sequences mdpi.com/1999-4915/11/5… in @VirusesMDPI Avraam’s unusual and creative method for analyzing short sequence reads applied to viral populations.

Petronela Buiga's article using Boolean modelling to study the role of dual specificity phosphatases in herceptin resistant breast cancer is published in Computational Biology and Chemistry. @elabuiga doi.org/10.1101/528315

Great work @victor_faundes @smbanka @ManchesterBRC @MFT_Genomics @OfficialUoM @EvolSysGen international collaboration

MRC/UoM Confidence in Concept (CIC) #7 is now open! Funding available to support studies that would overcome a particular hurdle, to accelerate the transition from discovery research to translational development. Full details staffnet.manchester.ac.uk/bmh/research/f…

Looking forward to speaking about our genetic studies @MFT_Genomics @EvolSysGen @OfficialUoM on rare bladder disorders #ESPU2019

MRC/UoM Confidence in Concept (CIC) #7 is now open! Funding available to support studies that would overcome a particular hurdle, to accelerate the transition from discovery research to translational development. Full details staffnet.manchester.ac.uk/bmh/research/f…

Method for handling large-scale time-course single cell data, for a wide range of data types, including RNAseq, qPCR, microarrays, and more: Ahmed et al. (w/ @MagnusRattray & @Boukouva1Alexis) GrandPrix: scaling up the Bayesian GPLVM for single-cell data academic.oup.com/bioinformatics…

Airway epithelial cells actively clear pathogens. This review explains four mechanisms: Bertuzzi et al. (w/ @MFIG_Bignell) Microbial uptake by the respiratory epithelium: outcomes for host and pathogen in @FEMSTweets's #FEMSMicrobiologyReviews academic.oup.com/femsre/article…

A few of the recent papers from members of the Domain highlighted in the April 2019 Newsletter. Want to see yours here? Let us know or tag us @EvolSysGen