MVermeulenLab

10/ We next wished to explore PRC2 integrity in the absence of AEBP2 isoforms with @LabVermeulen. We found that while loss of either isoform reduced JARID2 incorporation, JARID2 in PRC2.2 can associate with either isoform, or even without both

@OdedRechavi Congratulations Oded, I am going to try it! :)

BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 It started from my frustration with the depressing effect that the current publishing system has on the well-being of myself, my team, and pretty much every scientist I know (maybe you’ve noticed from my stupid jokes… :) I was exhausted of dealing with the huge delays, reviewers that can be abusive, and how arbitrary it all is. Unfortunately, the most important factors are often WHO your reviewers are and who YOU are... It’s clear we need alternatives or at least ways to improve the situation. So, together with a really special and talented team we worked to develop this idea into “qed” a platform where you can get CONSTRUCTIVE feedback on your own work or CRITICALLY assess other people’s papers. It can be a real difference maker if many of you join us (thousands have tried it already, but today we release a NEW and much stronger version ;) Let’s harness qed to put the power back in the scientists’ hands, to do, to read & to publish science on our own terms. I’m dying for you to TRY IT, and it’s very simple - just drop a paper (the link to the website is in the replies👇) - it’s completely secure, private, and free, and you get results fast. Please show your support, SHARE, tell your friends, and let’s be the revolution 🫵!

EEE meeting is BACK! Early Embryogenesis & Epigenetics conference in Berlin 02/2026. Checkout great program and over 12 slots for (not so) short talks for submitted abstracts!. Early registration now open - molgen.mpg.de/embryo2026

New Preprint Alert! We combined microfluidics, proteomics, and RNA-seqto map spatiotemporal protein expression during mouse somitogenesisand found a novel regulatory strategy: dynamic antagonistic gradients fine-tune signalling strength. doi.org/10.1101/2025.0…

Dear Friends, family and colleagues, in two weeks, we will be participating in Alpe d'HuZes to raise money for cancer research. Would you like to support us? Please see the link below. Thank you so much in advance! opgevenisgeenoptie.nl/s/26886/34047/t

We have an open PhD position in my team at @Radboud_Uni on the fate of aneuploid cells during human embryogenesis. @ZonMw open collaboration w/ Maastricht Uni & MUMC+ @E_Vrij, Stefan Giselbrecht, Edith Coonen. Info/apply (before Jun 1st): lnkd.in/eEnFQUa8, or send me a PM.

Researchers have genetically altered a mouse to express traits reminiscent of the long-extinct woolly mammoth, including a long, coarsely textured coat, to create the woolly mouse. scim.ag/3QO97Ui @NewsfromScience

Check our our latest paper, the PRC1 and PRC2 proximal proteome in mouse ESCs, a study full of surprises! :) Spearheaded by Dick Zijlmans, Suzan Stello and Danique Bax, in a great collaboration with Hendrik Marks' lab and others! cell.com/cell-reports/f…

We’re Hiring: We are looking for a motivated Postdoctoral Researcher for a three-year funded position to contribute to cutting-edge melanoma research as part of the PerMel-AI consortium, funded by EP PerMed. See more details in rug.nl/about-ug/work-… #Proteomics #Bioinformatics

We have a new article out in collaboration with @LabVermeulen ! Photoaffinity probes based on Olaparib for Proteomic profiling. Simple but powerful! 💪 Read here: …mistry-europe.onlinelibrary.wiley.com/doi/abs/10.100…

📢 Applications for the NKI PhD program now open till Feb 28. Several exciting positions available, including one in my lab on discovering new biology and therapeutic opportunities of a population of enriched tumor-reactive T cells we recently identified. nki.nl/careers-study/…

@FrankSobott Happy holidays Frank and all the best for 2025, onwards and upwards! :)

I'm glad the year is over soon. It's had its clear Ups but also been outright toxic at times, and it's affected me. Looking forward to another PhD viva and then some well-earned off(line) time. For those left here, have a nice break!

@LaszloTora It was great, thanks again! :)

The very successful 5th Danube Epigenetic Conference, Budapest (Hungary) is slowly coming to an end. See you in two years!

@OdedRechavi 😂

Signing a PDF

👀 We're looking for a junior group leader! Join our innovative, curiosity-driven institute in a collaborative, international environment. Full freedom to pursue your research, competitive salary & relocation support. 📅 Apply by Dec 1 Info & application: bit.ly/3BLA3j8

📢van Rheenen lab is looking for an enthusiastic physician-researcher. For more details, check out the links below: nki.nl/careers-study/… werkenbijavl.nl/vacatures/md-p… Retweets are appreciated😇

We are hiring a PhD student in our lab to discover the genetic code and regulatory innovations underlying the evolution of human blastocyst implantation. Our new colleague will use human blastoids, advanced single-cell genomics and bioinformatics approaches. Please join us!

@vanRheenen_Lab @Nature Great paper, congratulations Jacco, Colinda and teams!!

New publication alert🚨🚨🚨Mechanisms that clear mutations drive field cancerization in mammary tissue is out @Nature nature.com/articles/s4158… Congratulations all for this great team work! 🎉

An update of #StemCell #EmbryoModels of #gastrulation onlinelibrary.wiley.com/doi/epdf/10.10… emphasis on #gastruloid 'cause, as shown on Table, people can work w/them. Still early days, much to learn but same experiment gives same result in different labs. @da40cambs #InNumbersWeTrust